The mouse feels comfortable, but there is not a lot of space left for the thumb rest, so the finger will basically mostly sit on the two left programmable buttons. We did really enjoy the silent sound signature of both left and right click buttons, while the scroll wheel is smooth and does not produce a disturbing sound when rotated. Depending on your hand size, you will use it in either a palm grip or fingertip grip, while the textured plastic will make sure your fingers won’t slip and there will be little to no wear to the surface in time.