Shirley D'Sa^1*, Josephine M.I. Vos^2*, Wilma Barcellini, MD^3*, Marek Wardęcki^4*, Laurent Perrin^5*, Graham Barker^6*, Moshe Zilberstein^7*, Michael Storek^8*, Timothy Chow^8* and Alexander Röth, MD⁹

¹UCLH Centre for Waldenström’s Macroglobulinemia and Related Conditions, University College London Hospitals NHS Foundation Trust, London, United Kingdom
²Amsterdam UMC, University of Amsterdam & Sanquin, Amsterdam, Netherlands
³Fondazione IRCCS Ca’ Granda Ospedale Maggiore Policlinico, Milan, Italy
⁴Sanofi, Warsaw, Poland
⁵Sanofi, Montpellier, France
⁶Sanofi, Chilly-Mazarin, France
⁷Sanofi, Bridgewater, NJ
⁸Sanofi, Cambridge, MA
⁹Department of Hematology and Stem Cell Transplantation, University Hospital Essen, University of Duisburg-Essen, Essen, Germany

Karolina Dziewulska-Cronk^1*, Julie A Reisz, PhD^2*, Travis Nemkov, PhD^3*, Ariel M Hay^4*, Aaron Issaian^3*, Francesca Cendali, BS⁵, Monika Dzieciatkowska, Ph.D^6*, Fabia Gamboni^7*, Derek Lamb, BSc^8*, Mitasha Palha^9*, Joseph Kao^9*, Paul Buehler, PharmD, PhD^8*, Angelo D'Alessandro, PhD², Robert Commons^10* and James C Zimring, MD, PhD^1*

¹University of Virginia School of Medicine, Charlottesville, VA
²Biochemistry and Molecular Genetics, University of Colorado Anschutz Medical Campus, Aurora, CO
³University of Colorado Anschutz Medical Campus, Aurora, CO
⁴University of Virginia, Charlottesville, VA
⁵University of Colorado School of Medicine, Anschutz, Aurora, CO
⁶University of Colorado Denver - Anschutz Medical Campus, Aurora, CO
⁷University of Colorado, Aurora, CO
⁸Center for Blood Oxygen Transport and Hemostasis, University of Maryland, Baltimore, MD
⁹University of Maryland, Baltimore
¹⁰Menzies School of Medicine, Darwin, Australia

Thidarat Suksangpleng, PhD¹, Kalaya Tachavanich, M.Sc.^2* and Vip Viprakasit^2*

¹Faculty of Medicine Siriraj Hospital, Siriraj Thalassemia Center, Mahidol University, Bangkok, Thailand
²Faculty of Medicine Siriraj Hospital, Department of Pediatrics, Mahidol University, Bangkok, Thailand

Chloé Turpin, PhD¹, Arwa Fraiwan, PhD^1* and Umut A. Gurkan, PhD²

¹Case Western Reserve University, Cleveland, OH
²Department of Mechanical and Aerospace Engineering, Case Western Reserve University, Shaker Heights, OH

Christina Jurotich, BS^1*, Jeong-Ah Kim, PhD^1*, Kirby D. Johnson, PhD^1*, Siqi Shen, MS^2*, Ruiqi Liao, PhD^1*, Jane E Churpek, MD, MS³, Sunduz Keles, PhD^2* and Emery H. Bresnick, PhD⁴

¹School of Medicine and Public Health, Wisconsin Blood Cancer Research Institute, Department of Cell and Regenerative Biology, University of Wisconsin - Madison, Madison, WI
²Department of Biostatistics, University of Wisconsin - Madison, Madison, WI
³Department of Medicine, The University of Wisconsin-Madison, Madison, WI
⁴School of Medicine and Public Health, Wisconsin Blood Cancer Research Institute, Department of Cell and Regenerative Biology, Carbone Cancer Center, University of Wisconsin-Madison, Madison, WI

Isabelle Bouyssou, PhD^1,2*, Sara El Hoss, PhD^3*, Cécile Doderer-Lang^4*, Matthieu Schoenhals, PhD^5*, Lova Tsikiniaina Rasoloharimanana^5*, Inès Vigan-Womas^6*, Arsène Ratsimbasoa^7*, David C Rees, MBBS³, Andargie Abate^8*, Lemu Golassa, PhD^8*, Solenne Mabilotte^4*, Micheline Guillotte^2*, Francisco J. Martinez Blazquez^2*, Chetan E. Chitnis^2*, John Strouboulis, PhD^3* and Didier Ménard, PhD^1,2,4,9*

¹Malaria Genetics and Resistance Unit, INSERM U1201, Institut Pasteur, Université Paris Cité, Paris, France
²Malaria Parasite Biology and Vaccines Unit, Institut Pasteur, Université Paris Cité, Paris, France
³Red Cell Haematology Lab, School of Cancer and Pharmaceutical Sciences, King's College London, London, United Kingdom
⁴Institute of Parasitology and Tropical Diseases, UR7292 Dynamics of Host-Pathogen Interactions, University of Strasbourg, Strasbourg, France
⁵Immunology of Infectious Diseases, Institut Pasteur of Madagascar, Antananarivo, Madagascar
⁶Institut Pasteur de Dakar, Dakar, Senegal
⁷Faculté de Médecine, Université de Fianarantsoa, Fianarantsoa, Madagascar
⁸Aklilu Lemma Institute of Pathobiology, Addis Ababa University, Addis Ababa, Ethiopia
⁹Laboratory of Parasitology and Medical Mycology, CHU Strasbourg, Strasbourg, France

Travis Nemkov, PhD^1*, Emeric Stauffer, MD, PhD^2*, Francesca Cendali, BS³, Daniel Stephenson, PhD^4*, Elie Nader, PhD^5*, Melanie Robert, PhD^6*, Sarah Skinner, PhD^7*, Ian LaCroix^8*, Monika Dzieciatkowska, Ph.D^9*, Kirk C Hansen, PhD^1*, Guillame Millet, PhD^10*, Philippe Connes, PhD^11* and Angelo D'Alessandro, PhD¹²

¹University of Colorado Anschutz Medical Campus, Aurora, CO
²Laboratoire Interuniversitaire De Biologie De La Motricité (LIBM) EA7424, Université Claude Bernard Lyon, Villeurbanne, FRA
³University of Colorado School of Medicine, Anschutz, Aurora, CO
⁴Department of Biochemistry and Molecular Genetics, University of Colorado Denver, Aurora, CO
⁵Université Claude Bernard Lyon, Villeurbanne, France
⁶UR4609, Universite Lyon 1, Lyon, France
⁷Université Claude Bernard Lyon 1, Lyon, France
⁸University of Colorado Anschutz Medical Campus, Aurora
⁹University of Colorado Denver - Anschutz Medical Campus, Aurora, CO
¹⁰Université Jean Monnet, Saint-Etienne, France
¹¹Université Claude Bernard Lyon, Villeurbanne, FRA
¹²Department of Biochemistry and Molecular Genetics, University of Colorado Anschutz Medical Campus, Aurora, CO

Ashwin P. Patel, MD, PhD, MPH¹, Celeste K. Kanne, MS¹, Elizabeth O Stenger, MD, MSc², Tami D. John, MD^3* and Vivien A. Sheehan, MD, PhD¹

¹Aflac Cancer and Blood Disorders Center, Children's Healthcare of Atlanta, Emory University School of Medicine, Atlanta, GA
²Aflac Cancer and Blood Disorders Center, Children's Healthcare of Atlanta/Emory University, Atlanta, GA
³Lucile Packard Children's Hospital, Stanford University, Los Altos, CA

Meghana Matur^1*, Yasin Uzun^2*, Yi Qiu, PhD³ and Suming Huang, PhD¹

¹Division of Pediatric Hematology/Oncology, Pennsylvania State University College of Medicine, Hershey, PA
²Department of Pediatric, Pennsylvania State University College of Medicine, Hershey, PA
³Department of Cellular and Molecular Physiology, Pennsylvania State University College of Medicine, Hershey, PA

Pamela L Brito, MSc^1*, Erica M.F. Gotardo^1*, Lucas F.S. Gushiken, PhD^1*, Flavia C. Leonardo^1*, Fernando Ferreira Costa, MD, PhD¹ and Nicola Conran, PhD²

¹Hematology and Transfusion Center, University of Campinas - UNICAMP, Campinas, Sao Paulo, Brazil
²Hematology and Transfusion Center, University of Campinas - UNICAMP, Campinas, Sp, Brazil

Yasmin Elgammal, MD, MSc^1*, Mary Risinger, PhD^2*, Ammar Husami^3*, Joseph Walden^4*, Sweta Gupta, MD^5*, Niketa C. Shah, MD⁶, James Boyer, MD⁷, Yasmina L. Abajas, MD⁸, Michael Winstead^9*, David W. Miller, MD¹⁰, Viviana Vidal-Anaya¹¹, Adrianna Vlachos¹², Ashutosh Lal, MD¹³, Arthur K. Ritchey, MD¹⁴, Robert Lorsbach^4,15*, Wenying Zhang^16,17*, Theodosia A. Kalfa, MD, PhD^1,17 and Omar Niss, MD^4,18

¹Cancer and Blood Diseases Institute, Cincinnati Children's Hospital Medical Center, Cincinnati, OH
²Cincinnati Children's Hospital, Cincinnati, OH
³Division of Human Genetics, Cincinnati Children’s Hospital Medical Center, Cincinnati, OH
⁴University of Cincinnati College of Medicine, Cincinnati, OH
⁵INDIANA HEMOPHILIA AND THROMBOSIS CENTER, INC., Carmel, IN
⁶Department of Pediatric Hematology Oncology and Stem Cell Transplant, Yale New Haven Children’s Hospital, Yale University, New Haven, CT
⁷Sentara Martha Jefferson, Charlottesville, VA
⁸UNC Blood Research Center, Chapel Hill, NC
⁹UNC Blood research Center, Chapel Hill, NC
¹⁰Novant Health Presbyterian Medical Center, Charlotte, NC
¹¹Cohen Children's Medical Center, New Hyde Park, NY
¹²Steven and Alexandra Cohen Children's Medical Center of New York, New Hyde Park, NY
¹³School of Medicine, University of California San Francisco Benioff Children's Hospital, Oakland, CA
¹⁴Children's Hosp. of Pittsburgh of UPMC, Pittsburgh, PA
¹⁵Cincinnati Children's Hospital Medical Center, Cincinnati, OH
¹⁶Division of Human Genetics, Cincinnati Children's Hospital Medical Center, Cincinnati, OH
¹⁷Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH
¹⁸Hematology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH

Yichao Zhou and Kyle J Hewitt, PhD

Department of Genetics, Cell Biology and Anatomy, University of Nebraska Medical Center, Omaha, NE

Edward Owusu Kwarteng, PhD and Michalis Agathocleous, PhD

Children's Medical Center Research Institute, UT Southwestern Medical Center, Dallas, TX

Yoann Zadro^1*, Margaux Lafaurie^2*, Maryse Lapeyre-Mestre^2*, Marc Michel^3* and Guillaume Moulis^2*

¹Toulouse University Hospital, Toulouse, France
²Toulouse University hospital, Toulouse, France
³Internal medicine department, Henri Mondor Hospital, APHP, Créteil, France

Arvindhan G. Nagarajan, PhD^1*, Nicholas Neeley, MS^1*, Paymon Doroodian^1*, Ane Olazabel^1* and Gary Kupfer, MD²

¹Department of Oncology, Georgetown University, Washington, DC
²Georgetown University Medical Center, Washington, DC

Lauren E. Merz, MD, MSc^1,2, Alexander Chaitoff, MD, MPH^3*, Angela C Weyand, MD⁴, Michael Fralick, MD, PhD^5* and Michelle Sholzberg, MDCM, MSc⁶

¹Mass General Brigham, Boston
²Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA
³Division of Pharmacoepidemiology and Pharmacoeconomics, Brigham and Women's Hospital, Boston, MA
⁴Department of Pediatrics, University of Michigan Medical School, Ann Arbor, MI
⁵University of Toronto, Toronto, ON, Canada
⁶Division of Hematology-Oncology, St. Michael's Hospital, Toronto, ON, Canada

Andreas Glenthoej, MD, PhD¹, Eduard J. Van Beers, MD, PhD^2*, Richard van Wijk, PhD^3*, Minke A.E. Rab^4*, Evelyn Groot, MSc^5*, Niels G Vejlstrup, MD, PhD^6*, Selma K Bendtsen, MSc^7*, Nina Toft, MD, PhD^7*, Jesper Petersen, PhD^1*, Jens Helby, MD, PhD^1*, Fatiha Chermat^8*, Pierre Fenaux, MD, PhD⁸ and Kevin H.M. Kuo, MD, FRCPC, MSc⁹

¹Danish Red Blood Cell Center, Department of Hematology, Copenhagen University Hospital - Rigshospitalet, Copenhagen, Denmark
²Center for Benign Hematology, Thrombosis and Hemostasis - Van Creveldkliniek, University Medical Center Utrecht, Utrecht University, Utrecht, Netherlands
³University Medical Center Utrecht, Utrecht, Netherlands
⁴Central Diagnostic Laboratory - Research, University Medical Center Utrecht, Utrecht, Netherlands
⁵Center for Benign Hematology, Thrombosis and Hemostasis - Van Creveldkliniek, University Medical Center Utrecht, Utrecht University, Utrecht, NLD
⁶Department of Cardiology, Copenhagen University Hospital - Rigshospitalet, Copenhagen, Denmark
⁷Danish Red Blood Cell Center, Copenhagen University Hospital - Rigshospitalet, Copenhagen, Denmark
⁸EuroBloodNet Association, Paris, France
⁹Division of Hematology, University of Toronto, Toronto, ON, Canada

David J. Young, MD, PhD¹, Tania Rene Machado, RN, BSN^2*, Raymond T. Doty, PhD^3*, Colin O. Wu, PhD^4*, Janis L. Abkowitz, MD⁵, William Savage, MD, PhD⁶ and Cynthia E. Dunbar, MD¹

¹Translational Stem Cell Biology Branch, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD
²Office of Research Nurses, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD
³Division of Hematology, Department of Medicine, University of Washington, Seattle, WA
⁴Office of Biostatistics Research, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD
⁵Department of Medicine, University of Washington, Seattle, WA
⁶Disc Medicine, Watertown, MA

Federica Pilo, MD^1*, Raffaella Origa^2*, Marianna Greco^3*, Giovanni Caocci, MD⁴, Giuseppe Lazzaro^3*, Eleonora Zaccheddu^2*, Antonietta Zappu^2*, Angela Mereu^3*, Martina Pettinau^3*, Marta Moi^3* and Giorgio La Nasa^3*

¹SC di Ematologia e CTMO,, Ospedale Oncologico di Riferimento Regionale "A. Businco", ARNAS "G. Brotzu", Cagliari, Italy
²SC Centro Microcitemie e Anemie Rare, Ospedale Pediatrico Microcitemico 'A. Cao', Università di Cagliari, Cagliari, Italy
³SC di Ematologia e CTMO, Ospedale Oncologico di Riferimento Regionale "A. Businco", ARNAS "G. Brotzu", Cagliari, Italy
⁴Department of Medical Sciences and Public Health, University of Cagliari, Businco Hospital, Cagliari, Italy