Sean Walulik^1*, Sarai Dean^1*, Eric J Vick, MD, PhD^2,3, Xiaoqin Zhu^4*, Mark Wunderlich, MS^1*, Chih-Hsing Chou, PhD^1*, Kwangmin Choi, PhD^3*, H. Leighton Grimes, PhD¹, Daniel T. Starczynowski, PhD³, Linde A. Miles, PhD⁵ and Andrew Volk, PhD⁶

¹Cincinnati Children's Hospital Medical Center, Cincinnati, OH
²Division of Hematology/Oncology, University of Cincinnati, Cincinnati, OH
³Division of Experimental Hematology and Cancer Biology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH
⁴Department of Cancer and Cell Biology, University of Cincinnati, Cincinnati, OH
⁵Division of Experimental Hematology & Cancer Biology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH
⁶Cincinati Childrens Hospital Medical Center, Cincinnati, OH

Lis Winter, MSc^1,2*, Lea Pawlowsky^1,2*, Anetta Marcinek, M.Sc.^1,2*, Bettina Brauchle, Ph.D.^1,2*, Amelie Muth, MSc^1,2*, Maryam Kazerani, Ph.D.^1,2*, Agnese Petrera, PhD^3*, Roman Kischel, MD^4*, Alica Joana Emhardt, MD^2*, Maja Rothenberg-Thurley, PhD^2*, Annika Maria Dufour, PhD, MSC^2*, Karsten Spiekermann, MD^2,5*, Michael Andreeff, MD PhD⁶, Naval Daver, MD⁶, Veit L. Buecklein, MD^1,2* and Marion Subklewe, MD^1,2,7

¹Laboratory for Translational Cancer Immunology, Gene Center, LMU Munich, Munich, Germany
²Department of Medicine III, LMU University Hospital, LMU Munich, Munich, Germany
³Metabolomics and Proteomics Core, Helmholtz Zentrum München, German Research Center for Environmental Health (GmbH), Neuherberg, Germany
⁴Amgen Research (Munich) Gmbh, Munich, Germany
⁵German Cancer Consortium (DKTK) Partner Site Munich, Munich, Germany
⁶Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX
⁷German Cancer Consortium (DKTK) and German Cancer Research Center (DKFZ), Heidelberg, Germany

Nam Nguyen, MS, PharmD¹, Phani Krishna Parcha, PhD^2*, Abderrahmane Tagmount, PhD^3*, Bailey Gregory^4*, Xueyuan Cao, PhD^5*, Stanley Pounds, PhD^6*, Christopher Vulpe, MD, PhD^7* and Jatinder K. Lamba, PhD⁸

¹Department of Pharmacotherapy and Translational Research, University of Florida College of Pharmacy, Gainesville, FL
²Department of Pharmacotherapy and Translational Research, College of Pharmacy, University of Florida, Gainesville, FL
³University of Florida, Gainesville, FL
⁴University of Florida College of Pharmacy, Gainesville
⁵Department of Health Promotion and Disease Prevention, University of Tennessee Health Science Center, Memphis, TN
⁶Department of Biostatistics, St. Jude Children's Research Hospital, Memphis, TN
⁷University of Florida College of Veterinary Medicine, Gainesville, FL
⁸Department of Pharmacotherapy and Translational Research, University of Florida, Gainesville, FL

Terra L. Lasho, PhD¹, Christy M Finke^1*, Jenna A. Fernandez, PhD^2*, Christopher T. Schmitz^3*, Karl J. Clark, PhD^3*, Claes Wahlestedt, MD PhD^4*, Judy Chiao, MD^4*, Abhishek A Mangaonkar, MBBS², Mrinal M. Patnaik, MD, MBBS² and Moritz Binder, MD⁵

¹Division of Hematology, Department of Medicine, Mayo Clinic, Rochester, MN
²Division of Hematology, Mayo Clinic, Rochester, MN
³Department of Biochemistry and Molecular Biology, Mayo Clinic, Rochester, MN
⁴Epigenetix Inc., Delray Beach, FL
⁵Mayo Clinic, Rochester, MN

Jiaqi Chen, PhD^1,2*, Lijun Wen, MD^3*, Xiaosu Zhou, PhD^4*, Xue Chen, MD^1*, Zhanglin Zhang, MD^5*, Panxiang Cao, MS^1,2*, Fang Wang, MD^1*, Yang Zhang, MD^1,2*, Xiaoli Ma, MD^1*, Jiangcheng Fang^1*, Ping Wu, MD^1*, Tong Wang, MD^1*, Zhihua Zhang, MD^6*, Linya Wang, MD^7*, Huyong Zheng, MD, PhD⁷, Ruijie Tang, MD^8*, Wei Wang, MD^9*, Wanting He, MD^9*, Siyuan Liu^2*, David Jin, MD^2*, Xian Zhang, MD^8*, Peihua Lu, MD^8,10*, Suning Chen, MD^3* and Hongxing Liu, MD^1,2,11,12

¹Department of Laboratory Medicine, Hebei Yanda Lu Daopei Hospital, Langfang, China
²Molecular Medicine Center, Beijing Lu Daopei Institute of Hematology, Beijing, China
³National Clinical Research Center for Hematologic Diseases, The First Affiliated Hospital of Soochow University, Jiangsu Institute of Hematology, Institute of Blood and Marrow Transplantation, Collaborative Innovation Center of Hematology, Soochow University, Suzhou, China
⁴Molecular Medicine Center, Beijing Lu Daopei Institute of Hematology, Beijing, AL, China
⁵Department of Transfusion, The First Affiliated Hospital of Nanchang University, Nanchang, China
⁶Affiliated Hospital of Chengde Medical University, Chengde, China
⁷Hematology Center, Beijing Children’s Hospital, Capital Medical University, National Center for Children’s Health, Beijing, China
⁸Department of Hematology, Hebei Yanda Lu Daopei Hospital, Langfang, China
⁹Department of Hematology, The Second Affiliated Hospital of Harbin Medical University, Harbin, China
¹⁰Beijing Lu Daopei Institute of Hematology, Langfang, China
¹¹Division of Pathology & Laboratory Medicine, Beijing Lu Daopei Hospital, Beijing, China
¹²Department of Oncology, Capital Medical University, Beijing, China

Chunhua Shi^1*, Ze Tian^1*, Jun Yan^1*, Mao Zhang^2*, Pariya Sukhumalchandra^2*, Edward Chang^1*, Guojun Yang^1*, Junping You^1*, Meng Cui^1*, Qing Shi^1*, Anne Philips^2*, Na Qiao^2*, Anna Sergeeva, PhD^3*, Lisa St. John^2*, Hong He, MD, PhD^3*, Dongxing Zha^4*, Jeffrey J. Molldrem, MD⁵ and Gheath Alatrash, PhD, DO²

¹Oncology Research for Biologics and Immunotherapy Translation (ORBIT), University of Texas MD Anderson Cancer Center, Houston
²Department of Hematopoietic Biology and Malignancy, University of Texas MD Anderson Cancer Center, Houston
³Department of Hematopoietic Biology and Malignancy, University of Texas M. D. Anderson Cancer Center, Houston, TX
⁴Alloy Therapeutics, Boston
⁵Department of Hematopoietic Biology and Malignancy, The University of Texas MD Anderson Cancer Center, Houston, TX

Hui Si Kwok, PhD^1*, Amanda Waterbury^1*, Ceejay Lee^1*, Domenic Narducci^2*, Allyson Freedy^1*, Cindy Su^1*, Andrew Reiter^3*, William Hawkins^3*, Kwangwoon Lee^4*, Jiaming Li^1*, Samuel Hoenig^1*, Michael Vinyard, BA^1*, Philip Cole^4*, Anders Hansen^2*, Steven A. Carr, PhD^3*, Malvina Papanastasiou^3* and Brian Liau^1*

¹Department of Chemistry and Chemical Biology, Harvard University, Cambridge, MA
²MIT Biological Engineering, Cambridge, MA
³Broad Institute of MIT and Harvard, Cambridge, MA
⁴Division of Genetics, Brigham and Women’s Hospital, Boston, MA

Emma Rabinovich, MD^1,2, Ariel Fromowitz^2,3, Opeyemi Ajibade, MD, MS^4*, Srabani Sahu^5*, Divij Verma, PhD², Sarah Aminov, MSc², Nandini Ramachandra, MS^5*, Christopher Selverian^2*, Nailya Khalizova^2*, Srinivas Aluri, PhD^5*, Rahul Sanawar, PhD^2*, Shanisha Gordon Mitchell^2*, Milagros Carbajal^2*, Jacqueline Boultwood, PhD^6*, Andrea Pellagatti, PhD^6*, Ulrich Steidl, MD, PhD², Aditi Shastri, MD², Rongbao Zhao, PhD^5*, Alexis Mollard, PhD^7*, Margit Janat-Amsbury^7*, David J. Bearss, PhD⁸, Alan F. List, MD⁷ and Amit Verma, MD²

¹Department of Bone Marrow Transplant, Memorial Sloan Kettering Cancer Center, New York, NY
²Blood Cancer Institute, Department of Oncology, Albert Einstein College of Medicine, Bronx, NY
³Department of Stem Cell Transplantation and Cellular Therapy, The University of Texas MD Anderson Cancer Center, Houston, TX
⁴Blood Cancer Institute, Department of Oncology, Albert Einstein College of Medicine, Brooklyn, NY
⁵Montefiore Einstein Cancer Center, Blood Cancer Institute, Department of Oncology, Montefiore Medical Center, Albert Einstein College of Medicine, Bronx, NY
⁶Bloodwise Molecular Haematology Unit, Nuffield Division of Clinical Laboratory Sciences, University of Oxford, John Radcliffe Hospital, Oxford, United Kingdom
⁷Halia Therapeutics, Lehi, UT
⁸Halia Therapeutics, Alpine, UT

Zhihong Zeng, MD¹, Annelies Roobrouck^2*, Geert Deschamps^2*, Helene Bonnevaux^3*, Stephane Guerif^3*, Veronique De Brabandere^2*, Amara Céline^3*, Eline Jonckheere^2*, Angela Virone-Oddos, PhD^4*, Marielle Chiron, PhD^4*, Melissa Dullaers^2* and Marina Y. Konopleva^1,5

¹Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX
²SANOFI R&D, Zwijnaarde, Belgium
³SANOFI R&D, Vitry-sur-Seine, France
⁴Sanofi R&D, Vitry-sur-Seine, France
⁵Department of Oncology, Montefiore Medical Center and Albert Einstein College of Medicine, Bronx, NY

Christine Birdwell, PhD¹, Warren C. Fiskus, BSc, PhD², Christopher Peter Mill, PhD, BA¹, Tapan M. Kadia, MD³, Naval Daver, MD³, Courtney D. DiNardo, MD, MSc³, Koji Sasaki, MD³, John Davis^1*, Kaberi Das^2*, Hanxi Hou^4*, Michele Ceribelli, PhD^5* and Kapil N. Bhalla, MD³

¹MD Anderson Cancer Center, Houston, TX
²UT MD Anderson Cancer Center, Houston, TX
³Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX
⁴The University of Texas MD Anderson Cancer Center, Houston, TX
⁵Division of Pre-Clinical Innovation Chemistry Technologies, National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, MD

Matthew Tcheng, PhD^1*, Aaron D. Schimmer, MD², Marcela Gronda^3*, Rose Hurren^3*, Shahbaz Khan, PhD^4*, Lan Xin Zhang^1*, Chaitra Sarathy, PhD^3*, Yongran Yan^2*, Andrea Arruda^5*, Thomas Kislinger, PhD^4* and Mark D. Minden^4*

¹University Health Network, Princess Margaret Cancer Center, Toronto, ON, Canada
²University Health Network, Princess Margaret Cancer Centre, Toronto, ON, Canada
³UHN, Princess Margaret Cancer Centre, Toronto, ON, Canada
⁴Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada
⁵Princess Margaret Cancer Centre, University Health Network, Toronto, Canada

Nadia El Khawanky^1,2*, Yunus Barth^1,2*, Tatiana Nedelko, Ph.D^1,2*, Marc Rosenbaum, Ph.D^2,3*, Christin Weiß, M.Sc^2,3*, Stefan Enßle, M.D^1,2*, Jürgen Ruland, M.D^2,3,4*, Florian Bassermann, MD^1,2,4* and Simon M Heidegger, M.D^1,2*

¹Department of Medicine III, School of Medicine, Klinikum rechts der Isar, Technical University of Munich, Munich, Germany
²TranslaTUM, Center for Translational Cancer Research, Technical University of Munich, Munich, Germany
³School of Medicine, Institute of Clinical Chemistry and Patho-biochemistry, Technical University of Munich, Munich, Germany
⁴German Cancer Consortium (DKTK), Heidelberg, Germany

Divya Jyoti Singh^1*, Metis Hasipek, PhD^2*, Dongxu Jiang, PhD^1,2, Daniel Vail, PhD^1*, Yahan Zhang, MS¹, Jill Durkin^1*, Naomi Kawashima, MD, PhD^1,2*, Simon Schlanger, MS^1*, Xiaorong Gu, PhD^1,2*, Jaroslaw P. Maciejewski, M.D., Ph.D., FACP², Yogenthiran Saunthararajah, MD², Hetty E. Carraway, MD, MBA³ and Babal Kant Jha, PhD^1,2*

¹Center for Immunotherapy & Precision Immuno-Oncology, Lerner Research Institute, Cleveland Clinic, Cleveland, OH
²Translational Hematology and Oncology Research (THOR), Cleveland Clinic, Cleveland, OH
³Taussig Cancer Institute, Leukemia Program, Cleveland Clinic, Cleveland, OH

Sean M. Post, PhD¹, Ashley G Rodriguez, MS^2*, Oscar Benitez^2*, Jared Brottem^2*, Irene Wang^3*, Joanne Chang^3*, Mark G. Frattini, MD, PhD⁴ and Abhishek Maiti, MD⁵

¹MD Anderson, Houston, TX
²MD Anderson, Houston
³LinBioscience, Taipei, Taiwan
⁴Cellectis, Inc., New York, NY
⁵Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX

Athena Phoa, PhD^*, Min Chen, PhD^* and Xiaoyan Jiang, MD, PhD

Terry Fox Laboratory, BC Cancer Research Centre, Vancouver, BC, Canada

Sudeep Prajapati^1*, Michael Cameron^1*, Bryan M. Dunyak^1*, Mengge Shan^1*, Y. Amy Siu^1*, Samantha Levin-Furtney^1*, Joshua Powe^1*, Eileen T.M. Burchfiel^1*, Sarah E. Cabral^1*, Alycen M. Harney^1*, Regina K. Keenan^1*, Kevin M. Larpenteur^1*, Jesper L.V. Maag^1*, Andrew R. Snyder^1*, Dan T. Nguyen^1*, Cecile Blaustein^1*, Silvia Buonamici², Dominic Reynolds^1*, Matthew J. Schnaderbeck^1*, Michael Seiler^1*, Frédéric H. Vaillancourt^1*, Peter Smith^1*, Zaven Kaprielian^1* and Charles Kung^1*

¹Remix Tx, Watertown
²Remix Tx, Cambridge, MA

Shira Glushakow-Smith^1,2,3, Imit Kaur, PhD^1,3*, Simone Sidoli, PhD^4*, Shayda Hemmati, PhD^1,3*, Ellen Angeles^1,3*, Taneisha Sinclair, MD^1,3*, Aaliyah Battle^1*, Amit Verma, MD^3,5,6 and Kira Gritsman, MD, PhD^1,2,3,7

¹Department of Cell Biology, Albert Einstein College of Medicine, Bronx, NY
²Department of Clinical Investigations, Albert Einstein College of Medicine, Bronx, NY
³Ruth L. and David S. Gottesman Institute for Stem Cell and Regenerative Medicine Research, Albert Einstein College of Medicine, Bronx, NY
⁴Department of Biochemistry, Albert Einstein College of Medicine, Bronx, NY
⁵Department of Developmental and Molecular Biology, Albert Einstein College of Medicine, Bronx, NY
⁶Department of Medical Oncology, Montefiore Medical Center, Albert Einstein College of Medicine, Bronx, NY
⁷Department of Medical Oncology, Montefiore Medical Center, Bronx, NY

Meiling Chen^1,2*, Chao Shen, PhD^1*, Yi Chen, MD^2*, Keren Zhou, PhD^1*, Wei Li, PhD^1*, Zhenhua Chen, PhD^1*, Chengwu Zeng, PhD^1*, Ying Qing, PhD^1*, Dong Wu, PhD^1*, Kitty Wang^1*, Xiaolan Deng, PhD^1*, Jianda Hu, PhD^3,4, Yong Wu, MD, PhD^2* and Jianjun Chen, PhD¹

¹Department of Systems Biology, Beckman Research Institute, City of Hope, Monrovia, CA
²Fujian Institute of Hematology, Fujian Provincial Key Laboratory on Hematology, Fujian Medical University Union Hospital, Fuzhou, China
³Fujian Institute of Hematology, Fujian Provincial Key Laboratory on Hematology, Union Hospital, Fujian Institute of Hematology, Fuzhou, China
⁴Department of Hematology, The Second Affiliated Hospital of Fujian Medical University, Quanzhou, China

Yun Zhang, PhD^*, Sara Nadworny^*, Shengwu Liu, PhD^*, Sen Zhang, PhD^*, Emily Ye^*, Narayana Narasimhan, PhD^*, David C Dalgarno, PhD^*, Justin Pritchard, PhD^*, Wei-Sheng Huang, PhD^*, William C Shakespeare, PhD^* and Victor M Rivera, PhD

Theseus Pharmaceuticals, Cambridge, MA

Kailen Mark^1*, Minyoung Youn, PhD^1*, Madalsa Singh^1,2* and Kathleen M. Sakamoto, MD, PhD³

¹Department of Pediatrics, Stanford University School of Medicine, Stanford, CA
²Department of Biological Sciences, San Jose State University, San Jose, CA
³Department of Pediatrics, Stanford University, Stanford, CA

Charles Okechukwu^1*, Kristin Pladna, MS^2*, William Gmeiner, PhD^3* and Timothy S Pardee, MD, PhD²

¹Cancer Biology, Comprehensive Cancer Center of Atrium Health Wake Forest Baptist, Winston-Salem, NC
²Comprehensive Cancer Center of Atrium Health Wake Forest Baptist, Winston-Salem, NC
³Wake Forest School of Medicine, Winston-Salem, NC

Margaret C. Lunn^1*, George S. Laszlo, PhD^1*, Sarah Eraiss^1*, Mark T. Orr, PhD^2*, Heidi K. Jessup^2*, Henry Chan, PhD^3*, Heather J. Thomas^2*, Ann F. Cheung, PhD^4*, Gregory P. Chang^4*, Asya Grinberg, PhD^4*, Eduardo Rodríguez-Arbolí, MD^1*, Sheryl Y. T. Lim, DPhil^1*, Allie R. Kehret^1*, Jenny Huo^1*, Frances M. Cole^1*, Samuel C. Scharffenberger^1* and Roland B. Walter, MD, PhD, MS^1,5,6

¹Translational Science and Therapeutics Division, Fred Hutchinson Cancer Center, Seattle, WA
²Bristol Myers Squibb, Inc, Seattle, WA
³Bristol Myers Squibb, Inc, San Diego, CA
⁴Dragonfly Therapeutics, Inc, Waltham, MA
⁵Division of Hematology, Department of Medicine, University of Washington, Seattle, WA
⁶Department of Laboratory Medicine and Pathology, University of Washington, Seattle, WA

Chi-Yang Tseng¹, Yu-Hsuan Fu, MS², Ching-Ying Kuo, Ph.D.^3*, Hsin-An Hou, M.D.; Ph.D.⁴, Da-Liang Ou, Ph.D.^5* and Liang-In Lin, PhD⁶

¹Clinical Laboratory Sciences and Medical Biotechnology, National Taiwan University, New Taipei City, Taiwan
²Department of Hematologic Malignancies Translational Science, Gehr Family Center for Leukemia Research, City of Hope National Medical Center and Beckman Research Institute, Duarte, CA
³Department of Clinical Laboratory Sciences and Medical Biotechnology, National Taiwan University, Taipei, Taiwan
⁴Division of Hematology, Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan
⁵Graduate Institute of Oncology, National Taiwan University, Taipei, Taiwan
⁶Clinical Laboratory Sciences and Medical Biotechnology, National Taiwan University, Taipei, Taiwan

Hiroaki Konishi^*, Yuki Murakami, MD, PhD^*, Elizabeth Helmke^*, Jan Michael A Lerot^* and Noriko Satake, MD

Department of Pediatrics, University of California, Davis, Sacramento, CA

Danny Jeyaraju, PhD^1*, Ann Polonskaia^1*, Chih-Chao Hsu, PhD^1*, Patrick R Hagner, PhD^1,2* and Anita K. Gandhi, PhD¹

¹Translational Development and Diagnostics, Bristol Myers Squibb, Summit, NJ
²Celgene Corporation, Summit, NJ

Beatrix Stelte-Ludwig, PhD^1*, Tibor Schomber, PhD^1*, Raquel Izumi, PhD², Harvey Wong, PhD^2*, Melanie M Frigault, PhD^2*, Anne-Sophie Rebstock, PhD^1*, Sebastian Ludwig, PhD^1*, Arushi Mithal^2*, Amy J Johnson, PhD² and Ahmed Hamdy, MD²

¹Vincerx Pharma GmbH, Monheim, Germany
²Vincerx Pharma, Palo Alto, CA