SimVantage

𝗢𝘂𝗿 𝗔𝗔𝗧𝗠 𝟮𝟬𝟮𝟱 𝗦𝗽𝗼𝗻𝘀𝗼𝗿𝘀! With almost two weeks to go, the Accelerating Access to Medicines workshop is fast approaching! This event is made possible thanks to the support of our sponsors. We’re proud to partner with ABA - INVEST in AUSTRIA, Austrian Federal Economic Chamber, ZETA, Syntegon, Siemens, LoconIQ, InSilicoTrials, Human.technology Styria GmbH and SimVantage, whose contributions play a key role in making this event happen. Be sure to connect with them during the workshop to learn more about their work and impact on the industry. Join us on April 1-2, 2025, as we bring together industry leaders, regulators, and experts for two days of insightful discussions. Find out more here: https://lnkd.in/dWWBMKyg #AATM2025 #PharmaInnovation #PharmaceuticalDevelopment

🔎  What do #bioprocesses & #leadership have in common? More than you’d think! At the Human.technology Styria GmbH meeting at Roche Vienna last week, it wasn’t just about partnerships & innovation - but also about the art of breaking down complex challenges. And with such a highly engaging program, there was plenty to take away! 💡 Highlight: Talking to Susanne Erkens-Reck (GM Roche Pharma Austria). Her strategy? Decomposing big problems into smaller, solvable units - just like we do in bioprocess simulation. And her pay-it-forward approach to #mentoring shows how knowledge transfer creates real impact. 🚀  Start-up insights: A great exchange with Katrin Susanna W. (Lanbiotic) on the highs & lows of the start-up journey - and the courage it takes to bring biotech innovations to market. Her company is developing an innovative skin cream for neurodermatitis - a real gamechanger for many affected! 🌎  The biotech world is small! Our CEO and Gerald Neudorfer (HINKE Tankbau GmbH) realized they come from the same hometown - Schwanenstadt. Sometimes, the best connections happen by chance! What’s your most inspiring #networking moment? Drop it in the comments! 👇

🚀  From theory to practice - SimVantage at Provadis Hochschule in Frankfurt am Main! Last Friday and Saturday, we had the opportunity to bring #CFD & #bioreactorsimulations directly into the classroom at Provadis Hochschule. Thanks to Prof. Thomas Bayer, we hosted a guest lecture on reactor simulation - and even better, we got hands-on with our software together with the students. 🎓  The reaction? Enthusiasm! Seeing real-time simulation results and gaining deep insights into fluid dynamics sparked real excitement. Some students, already working in the field, compared our software to other tools - highlighting key takeaways: 💡 our physics-based approach delivers more advanced results, 💡  while other tools often offer more extensive & simplified input options. This direct feedback from future industry professionals is invaluable - it helps us make our software even more intuitive and impactful for everyday use! One discussion stood out: The history of #CFD tools and where we stand today. The evolution of simulations has been incredible, and we’re excited to be part of the next leap forward. 🙌 Big thanks to all the students who actively joined the discussion! Your insights and curiosity made this an inspiring experience. 🔧  What do you think? What’s the biggest challenge in CFD adoption?

Our first booth. Our first big stage. And yes - we’ll admit it: It feels like a pretty big deal. Because it’s not just about setting up a stand. It’s about showing who we are. What we stand for. And why we believe #bioreactorsimulations should be faster, easier, and better. But here’s the thing: What makes a booth worth stopping by? 👉  What’s the one giveaway you’d actually want to take home? 👉  Do you prefer a cozy spot to sit and chat - or just a high table for a quick stop?  👉 A demo on the big screen or hands-on with a laptop? We want to get this right. And we’d love your input! What do you enjoy most when visiting a trade show? Drop your thoughts below 👇 - and maybe you’ll spot your idea live at Booth No. 44. #DBT2025, here we come. 💥

🔬 Why do we use LES - and why is it often too slow with conventional #CFD? Turbulence modeling is crucial for accurate bioreactor simulations. Many traditional CFD approaches rely on RANS - a fast model that oversimplifies fine details. LES (Large Eddy Simulation), on the other hand, captures turbulent structures with high precision. But there’s a catch: It’s extremely computationally intensive. 🚀 This is where Lattice Boltzmann changes the game. Instead of conventional CFD methods, we leverage a GPU-based Lattice Boltzmann approach, enabling LES simulations at significantly higher speeds - without compromising accuracy. Why does this matter? ✅ More detail: Accurate representation of mixing processes & shear forces. ✅ Faster than traditional LES: GPU-based computing makes detailed bioreactor simulations feasible. ✅ Highly adaptable: Can be combined with VOF for complex gas-liquid systems. With this combination, we achieve the precision of LES at a speed that makes it practical for industrial applications. - 💡 Fast simulations, no long waits - just like the perfect way to head into the weekend, don’t you think? Enjoy your weekend, everyone! 👋 ☀️ - 🧐 P.S. Which approach do you use for your #simulations?

The true love of SimVantage? In #bioprocessing, it’s like in real love: 💔 We don’t want unpleasant surprises - just accurate, reliable results. 🩵 The right shear rate keeps your #cells happy and thriving. 💡 Optimal mixing ensures #consistency and #growth, every single time. When everything matches perfectly, that’s what we call true love. 🫶 In this spirit: Happy Valentine’s Day from SimVantage! 💐 May you find true love - just like we did.

💡 Don’t let innocent cells die - do you scale up on the computer first!   Scaling a bioprocess sometimes feels like uncharted territory. What works beautifully in a 5-liter lab reactor can fail catastrophically at 500 liters.   👩🔬 Poor mixing. 🌬️ Inadequate oxygen transfer. 💥 Excessive shear forces.   Sound familiar?   A process engineer recently shared this with us: "Our results in the 5-liter bioreactor looked promising. But at 500 liters? Everything fell apart. The cells were highly sensitive to increased oxygen transfer, and our yields plummeted. Weeks of troubleshooting later, we pinpointed the problem. But the delay was costly."   Stories like this happen all the time. Scaling isn’t just science - it’s an art.   That’s why we developed the new Scaler-Tool, launching in 2025. 🚀   ✔ Simulates mixing, flow dynamics, and oxygen transfer with precision. ✔ Eliminates guesswork and scaling risks. ✔ Delivers critical parameters in minutes - not weeks.   Be among the first to try it! 👇   Because every step toward #precision and #efficiency unlocks the full potential of #bioprocessing.   What’s your biggest challenge when scaling up? Drop your insights below 💬

2025, here we come! 🧗   Yes, it’s a little late - but we’d like to officially welcome you to the new year. 🎉 2025 is looking to be a climb - sometimes steep, challenging, but hopefully rewarding. Here are our key milestones so far:   🌎 Participation in RCPE - Research Center Pharmaceutical Engineering GmbH Goes to Washington (April 1–2): At this global event, we’ll connect with industry leaders, present innovative solutions, and highlight how SimVantage is driving advancements in process development.   🏢 Exhibition booth at the Deutsche Biotechnologietage (DBT) (April) organized by BIO Deutschland e. V.: We’ll have our very own booth in Heidelberg, the perfect basecamp for discussing simulation breakthroughs and connecting with biotech and pharma innovators in the DACH region.   🛠️ Attendance at the Global Bioprocessing Summit in Berlin (May) organized by KEYNOTION: We’ll be showcasing the latest features of our software while engaging with thought leaders and pioneers in bioprocessing.   🚀 Launch of the new scaling tool: Inspired by your feedback, our new scaling tool is almost ready. Designed to tackle scaling challenges with ease and precision, we can’t wait to share this game-changing solution with you!   🌐 Release of a new website: To enhance your experience, we’re working on a redesigned, user-friendly website that will make it easier than ever to explore SimVantage’s tools and resources.   📣 Improve communication: What insights would you like to see from us? What technical features of our tools should we highlight? In 2025, we aim to share more knowledge and strengthen our connection with you.   🎯 Reaching the 1,000-follower milestone on LinkedIn: This is an important goal for us, and with your support, we know we’ll get there!     👉 Want to join us on this journey and stay updated? Then follow us!

✨ BNN spotlights Early Career Researchers ✨ Philipp Eibl is CTO and co-founder of SimVantage, one of our newest members! His team is working on novel approaches to simulate all the necessary physics in #bioprocessing production equipment in order to better understand why the development of these processes often doesn’t yield the desired output, takes longer than expected or simply fails. Specifically, they are using #GPU-powered algorithms to quantify the environment of each individual microorganism within a biotechnological reactor. This allows them to address bottlenecks on the productivity of such processes with far more certainty than any experiment could tell you. We interviewed Philipp in our December 2024 QUARTERLY. Read the full article via the link in the comments!

Can someone please pinch us? How is it possible that 2024 is already coming to an end? It feels like the year flew by in no time. But here we are - reflecting on everything we’ve achieved together. And wow… what a year to remember. Here are a few highlights we’re most proud of: ✨ Advancing life sciences as part of the ECOnti consortium. 🏆 Celebrating the Claus Award, a shared milestone in our collective journey. 💡 Driving innovation at #ESACT2024 in Edinburgh, where we co-hosted a workshop with QUBICON and Novasign. 🌐 Welcoming Kaleidosim Cloud Technology to the SimVantage family, accelerating simulation solutions for all of you. But this is just the beginning. With 2025 on the horizon, we’re gearing up for another exciting chapter: 🚀 Introducing our new Scaling Tool, a game-changer for scale-up and tech transfer processes - faster, simpler, and more reliable than ever. For now, we wish you and your team a joyful holiday season and a fantastic start to the new year. May it be shear-free, and may turbulence only exist in your #simulations! Thank you for being part of our journey. We’re so grateful for your support, and we can’t wait to see what we’ll achieve together in 2025. P.S. In the picture, you can see our team celebrating the year at our Christmas party at the elegant LEVIET restaurant in Graz. What makes us such a strong team? It might be our shared curiosity and openness to new ideas - like trying Vietnamese cuisine together! Whether it’s exploring fresh flavors or tackling complex challenges, we’re always ready to step out of our comfort zones and embrace the unknown. A heartfelt thank you also to the team once again for making this year so special. 🎄 ✨