Centre for Biomedical Technologies

We wish #CBT #PhD #HDR Candidates Keya Amarsee and Hoang Son Pham good luck in the inaugural Steven Sylvander #Research #Communication #Challenge #SSRCC on 30 October. They will present their #cancer research in 3 minutes using only 1 slide. Thank you for arranging this event, Australasian College of Physical Scientists and Engineers in Medicine. 👩🏻🔬 Keya's topic: Improving accuracy in skin cancer treatment. Supervisors: Dr Marie-Luise Wille, Prof Davide Fontanarosa, A/Prof Scott Crowe, Dr Samuel Peet and D/Prof Dietmar W. Hutmacher 🧑🏻🔬 Son's topic: Application of in vitro 3D models to study the effect of hypofractionated radiation therapy for breast cancer. Supervisors: A/Prof Laura Bray, Dr Akhilandeshwari Ravichandran and A/Prof Larisa M Haupt #QUTResearch

🎉 One of our favourite days here at #CBT is #finalseminar days. In the spotlight today, Jordan Davern with his thesis: High-throughput #3D #bioprinting of the #tumor #microenvironment. Congratulations, Jordan (sitting in the photo surrounded by friends and colleagues) and his supervisors: Travis Klein, Laura Bray and Christoph Meinert, PhD. Thank you to today's panel: Yi-Chin Toh and Tim Dargaville #QUTResearch 🔬 Thesis Summary:  Three-dimensional (3D) bioprinting is an innovative technique that combines cells, molecules, and biomaterials to precisely pattern and assemble tissue-like structures. This method offers enhanced throughput compared to traditional manual preparation techniques, enabling the development of advanced in vitro models that accurately mimic key characteristics of native tissues, such as the breast tumor microenvironment. This thesis explores the development of bioinks and bioprinting processes, employing rheological workflows and computational fluid dynamics to predict and optimize bioprinting-associated shear stress. The research investigates the incorporation of multi-cellular constructs, composition, and stiffness to create a more accurate representation of the breast tumor microenvironment. By integrating increased cellular complexity and composition into an extrusion-based bioprinting system, this work achieves the enhanced throughput and precision required for the next generation of advanced in vitro models.

#CBT #academic #publishing Unravelling the #physicochemical and #antimicrobial mechanisms of human serum albumin/tannic acid coatings for medical-grade #polycaprolactone #scaffolds. Authors: Silvia Cometta, Akhilandeshwari Ravichandran, Yanan Xu, Nathalie Bock, Tim Dargaville and Dietmar W. Hutmacher in collaboration with (not photographed) Bogdan Donose, Alfredo Juárez-Saldivar and Aleksandar Rakić. Published in Science Direct / Bioactive Materials. Read more: https://lnkd.in/dAHsKPn5   Highlights 💡 Enhanced antimicrobial activity - Scaffolds coated with HSA/TA are effective against microbial growth for up to three days, which significantly reduces the colonization of S. aureus and prevents biofilm formation. 💡 Bacterial membrane disruption – Coated scaffolds cause morphological and mechanical alterations in S. aureus cell membranes, leading to membrane disruption and cell death. 💡Reinforced mechanical stability – Compared to their uncoated counterparts, mPCL scaffolds coated with HSA/TA demonstrated superior mechanical properties, which are crucial for their successful application as antibacterial implant coatings. 💡Biocompatible design - Coated scaffolds did not show any signs of cytotoxicity on in vitro cultured human cell sheets.   CBT October Academic Publication Highlights: XXX More publications from our Centre: https://lnkd.in/gwVZR7eR   #medicalmanufacturing #biomedical #medicalengineering #medicalinnovation #medicalresearch #medical #roboticsurgery #3dbioprinting #tissueengineering #biomechanics #collaboration #qut #QUTResearch

Very well-deserved recognition of fantastic #CBT #researcher, colleague and supervisor: Dr Jacqui McGovern! ISOLS International Society of Limb Salvage #sarcoma #ISOLS24BRISBANE #QUTResearch

We were delighted to welcome guest speaker Dr Alejandro Melendez-Calderon, who leads the NeuroEngineering, Rehabilitation and Medical Robotics Lab at The University of Queensland to the #CBT October Lunch Club. #PhD Candidates Anu Thomas Koikalethu received the #HDR of the Month #Award and Laura Milton the #Academic #Publication Award. Dr Andrew Stephens also shared experiences from his academic journey and PhD Candidate, Timo Baroth talked about his research project: Moving towards user-friendly, repeatable Melt Electrowriting. The event was hosted by Internal Engagement Lead, Jacqui McGovern Read more about the event and the speakers here: https://lnkd.in/gE62fspS The CBT Lunch Club events offer our HDR students and early career researchers an opportunity to give practice talks and be inspired by other researchers. We also award outstanding achievements and share success stories. #QUTResearch

Thank you, Dr Behnam Akhavan from the University of Newcastle for your guest talk on Plasma Bio-Engineering of Implantable Medical Devices.

🌟 We proudly present the #CBT July-September #Academic #Publication Highlight 🥇 Congratulations Laura Milton! 📚 Title of the winning article: Liver click dECM hydrogels for engineering #hepatic #microenvironments. Authors: Laura Milton, Jordan Davern, Luke Hipwood, Juliana Chaves, Jacqui McGovern, Daniel Broszczak, Dietmar W. Hutmacher, Christoph Meinert, PhD and Yi-Chin Toh. Published in Acta Biomaterialia Impact Factor: 9.7 (Q1/D1). Read the article here: https://lnkd.in/gcqXB5-A The Award was shared at our October Lunch Club, please read more about the event here: https://lnkd.in/gE62fspS Watch Laura talk about her upcoming Fulbright Association Futures Scholarship Adventure here: https://lnkd.in/gzC5iACv #QUTResearch

Vote here for Anu Thomas Koikalethu: https://lnkd.in/gHnntXgq Promega Corporation has nominated Anu for their Rising Researchers Scientific Innovation Award 2024. Read more and vote for Anu Thomas Koikalethu, PhD Candidate in Bone & Tumour Engineering at #CBT here: https://lnkd.in/gHnntXgq Voting closes 17 November. See all finalists here: https://lnkd.in/gs4X2zF9 Thank you, Promega for your 45 years of supporting scientists as a global biotechnology leader! Read more here: https://lnkd.in/dRwhJ8Pe #QUTResearch

Professor Tony Parker leads the Tissue Repair and Translational Physiology Group. He is interested in how human biochemistry and molecular biology can help us understand human injury, trauma and stress and how this knowledge can help predict health or human performance outcomes. Tony's team members in the video: Luke Schmidt, Sarah Ahamed and Jess Henning Enjoy more #CBT #researcher portraits: https://lnkd.in/eKASDZyJ #reserach #tissueengineering #biochemistry #molecularbiology #science #biomedtech #CBT #QUTResearch

#CBT #academicpublishing The Relationship between Placental Shear Wave Elastography and Fetal Weight - A Prospective Study. Authors: Erika Cavanagh, Davide Fontanarosa, Christoper Edwards, Marie-Luise Wille and Sailesh Kumar (not in photo) in collaboration with (not pictured) Kylie Crawford, Jesrine Hong, Jennifer Hong and Vicki Clifton. Published in MDPI / Journal of Clinical Medicine (JCM) MDPI Read more: https://lnkd.in/gKgzbsn5 The utility of shear wave elastography (SWE) as an adjunct to ultrasound biometry and Doppler velocimetry for the examination of placental dysfunction and suboptimal fetal growth is unclear. To date, limited data exist correlating the mechanical properties of placentae with fetal growth. This study aimed to investigate the relationship between placental shear wave velocity (SWV) and ultrasound estimated fetal weight (EFW), and to ascertain if placental SWV is a suitable proxy measure of placental function in the surveillance of small-for-gestational-age (SGA) pregnancies. CBT July - August Academic Publication Highlights: https://lnkd.in/gU-S2pAR More publications from our Centre: https://lnkd.in/gwVZR7eR #medicalmanufacturing #biomedical #medicalengineering #medicalinnovation #medicalresearch #medical #roboticsurgery #3dbioprinting #tissueengineering #biomechanics #collaboration #qut #QUTResearch