Deep Genomics

Thank you, Michael Eisenstein at Nature Magazine, for diving into the latest breakthrough in biology, AI foundation models. At Deep Genomics, we are finding new ways of accelerating discoveries in drug development and biotechnology leveraging the vast datasets of genetic, molecular, and cellular data these AI models can process. Not only does this innovation reshape how we approach complex challenges like disease diagnosis, it also sets the groundwork for personalized medicine and in turn, creates better patient outcomes. Brendan Frey was happy to contribute his expertise to the piece. A few of his thoughts below: “'A year and a half ago in our pitch, we would proudly talk about how we had 40 different machine learning models,' says Brendan Frey, founder and chief innovation officer of RNA drug discovery company Deep Genomics. Maintaining, scaling and integrating disparate models for predicting distinct yet intersecting biological processes such as RNA transcription, splicing or polyadenylation proved too challenging, however. As a solution, the company developed BigRNA, a foundation model that can make robust predictions about all these aspects of RNA biology — and more." "As more researchers begin to tinker with the models, Frey envisions opportunities ranging from accelerated discovery of new drugs for ultra-rare diseases to ‘multimodal’ models that integrate data from DNA, RNA, and protein to produce a more holistic perspective on the cellular interior. 'Eventually, I would hope we’ll start peeling back the cover on systems biology.'” To read more, check out the full article here 👉https://lnkd.in/eNv6nfPY #techbio #biology #DrugDiscovery #AIinnovation

At Deep Genomics, we are building an AI foundation model platform to design the next generation of RNA therapeutics. Today, we are excited to announce that we piloted one of the largest explorations into complex genetic conditions yet with Google Trillium TPUs. By leveraging a massive amount of computing power and Google’s specialized TPU architecture, we used one of our foundation models, BigRNA, to further our understanding of the genetic and biological determinants of complex and rare diseases. This will create a database that will drive therapeutic innovation for us and our partners. Read more about this pilot project here: https://lnkd.in/gWQti_Z3 #Innovation #RNATherapeutics #Genetics #TechBio

Today’s the day! Our Founder and CIO Brendan Frey is presenting our work on our foundation model platform, including BigRNA, DeepADAR and REPRESS, at the first RNA and AI Symposium hosted by UC San Diego’s RNA Center for Technologies and Therapeutics and Sanford Laboratories. We are in good company with other AI and biology experts in the room today and look forward to hearing about their research. What questions do you have for these academics and industry pros? Let us know in the comments below 👇 https://lnkd.in/guKysESx #UCSD #RNA #AITechnology #Academia #BiologyResearch 

We're #hiring a new Senior Machine Learning Engineer - Accelerating Drug Discovery with AI in Cambridge, Massachusetts. Apply today or share this post with your network.

Next week, the team is headed to sunny California for the inaugural RNA and AI Symposium presented by UC San Diego's RNA Center for Technologies and Therapeutics and Sanford Laboratories. Our CIO Brendan Frey will dive into the intersection of AI & machine learning and explore how AI serves as an accelerator in advancing RNA research and therapeutic innovations. Look out for some photos and takeaways from the event! https://lnkd.in/guKysESx #RNA #TechBio #AiInnovation #UCSD #MedicalInnovation

We are continuing our #teamspotlight series this week. We can’t wait to introduce you to Emily Lee MSHR! She is our Senior Director of Human Resources, leading the team that drives our employee experience and supports our employees from the moment they first join Deep Genomics. Get to know Emily’s background, experience and hobbies below. To join Emily and the rest of the Deep Genomics team, check out our open roles here: https://lnkd.in/gPDUaiug #deepgenomics #teamspotlight #toronto #boston #HR #leaders 

Did you know that our headquarters is in Toronto, Canada? 🇨🇦 The City of Toronto is one of Canada’s largest cities and a world leader in entertainment, business and technology—some of the many reasons Deep Genomics chose to set up shop here. If you’re planning a visit soon, here are some of our employees' favourite spots in town. 🖼️ The Royal Ontario Museum to escape a cold day and instead explore exhibits featuring art, world culture and natural history 🏘️ Walk through the Trinity-Bellwoods neighbourhood to support local artists and shops filled with interesting finds 🏰 Check out Toronto’s castle in the city, Casa Loma. They even have themed escape rooms to see the castle in a unique way Any that we missed? Let us know in the comments below 👇 #LifeAtDeepGenomics #Toronto #Innovation #Technology #CityofToronto

Congratulations to our very own Andrew Jung and his team for receiving the Best Poster Award earlier this month at the annual Oligonucleotide Therapeutics Society meeting. The winning poster described Deep Genomics’ work on DeepADAR, which uses deep learning to design ADAR gRNA sequences and accounts for structure—very timely given the recent Nobel Prizes. We are so proud of our team's innovative work! https://lnkd.in/gnQfJW2 #Innovation #TechBio #Research #TeamWins

We are so excited for Endpoints News first #AIDay. We will be tuning into the big talks of the day including the fireside chat with the Director of the University of Washington’s Institute for Protein Design and recent Nobel Prize laureate, David Baker, on the opportunities and challenges that lie ahead for the AI revolution in biology. As an AI-first #TechBio organization, we know the use of AI in pharmaceuticals has been met with some challenges in the past but we and many others in the space are on a mission to rewrite this narrative and are already seeing incredible results. From our creation of BigRNA, the first AI foundation model for decoding RNA biology and designing therapeutics, to our purpose-built multi-disciplinary team and culture, we are pioneering a new path for genomic R&D. We are thrilled to see more biologists and scientists recognize the power of AI for better health outcomes. What sessions are you looking forward to? Let us know in the comments 👇 https://lnkd.in/grNiSF9H #EndpointsNews #AI #AIinHealthcare #DrugDiscovery #innovation #futureofAI

Happy Thanksgiving to our Canadian team members! In case you didn’t know, Canada celebrates Thanksgiving a month earlier than the US 🇨🇦 This year, we are thankful for the amazing teams we have across our Deep Genomics offices. Whether you are enjoying your turkey today or in November, thank you for all that you do to bring our mission of #techbio innovation to life. #Thanksgiving #Canada #GlobalTeams