Allergy EAACI

Exciting News! We are thrilled to announce that Allergy has again achieved the third time the highest impact factor in allergy area ranking us as the 1 journal in the discipline of #Allergy and Clinical #Immunology. We want to extend our deepest gratitude to everyone who contributed to this success. Your commitment to excellence has made this possible. Thank you for being part of our journey towards advancing science. #Allergy_journal journalallergy.com

Wir freuen uns, ein bedeutendes neues Paper in Allergy EAACI unseres Instituts für Umweltmedizin und Integrative Gesundheit zu teilen! 🌿📄 Unsere Direktorin, Prof. Claudia Traidl-Hoffmann, ist als Koautorin maßgeblich daran beteiligt. Im Fokus steht die Epithelial Barrier Theory, die helfen könnte, den Anstieg chronischer Krankheiten seit den 1960er Jahren zu erklären. Über 350.000 neue chemische Substanzen sind seither in unseren Alltag eingezogen und könnten unsere Haut- und Schleimhautbarrieren schwächen. Diese Barriereprobleme führen zu mikrobieller Dysbiose und Entzündungen – und letztlich zu einer Zunahme an Krankheiten weltweit. Unser Forschungsteam beleuchtet in diesem Paper, dass viele dieser Krankheiten gemeinsame Mechanismen haben: gestörte Barrieren, Mikrobiome und systemische Entzündungen. Sogar scheinbar unabhängige Krankheiten treten immer häufiger zusammen auf. Es ist an der Zeit, chronische Erkrankungen neu zu verstehen – und innovative Ansätze zur Prävention zu entwickeln. #EpithelialBarrierTheory #Umweltmedizin #ChronischeKrankheiten #Forschung #Prävention #TeamScience #Gesundheit #TUNE (Co-Autorin: Prof. Dr. Claudia Traidl-Hoffmann) https://lnkd.in/dCJryYTR

Ich freue mich sehr und bin stolz, unser neuestes Paper Allergy EAACI zur Epithelial Barrier Theory zu teilen! 🎉 Diese Theorie könnte erklären, warum chronische #Krankheiten seit den 1960er Jahren immer häufiger werden. Über 350.000 neue chemische Substanzen sind seitdem in unseren Alltag eingezogen und beeinträchtigen möglicherweise unsere Haut- und Schleimhautbarrieren. Das Ergebnis? Mikrobielle Dysbiose, Entzündungen und letztlich eine Zunahme von Krankheiten. Unsere Forschung Helmholtz Munich Universität Augsburg Universitätsklinikum Augsburg zeigt, dass viele dieser Krankheiten ähnliche Mechanismen teilen: Barriereprobleme, gestörte #Mikrobiome und systemische #Entzündungen. Sogar Krankheiten, die auf den ersten Blick nichts miteinander zu tun haben, scheinen immer häufiger gemeinsam aufzutreten. Es wird Zeit, chronische Krankheiten neu zu denken – und insbesondere auch, wie wir sie verhindern können. Prävention ist der Weg der Zukunft im Gesundheitswesen, das heute eher ein Krankheitswesen ist! #Stolz #EpithelialBarrierTheory #ChronischeKrankheiten #Forschung #Umweltmedizin #Prävention #TeamScience (Co-Autorin: Prof. Dr. Claudia Traidl-Hoffmann) https://lnkd.in/dZhSjpmy

Visit our website journalallergy.com for news from our EAACI Junior Members 👉 bit.ly/3SEgiwX Read more on the latest JMA news and activities here 👉https://lnkd.in/dxCEAKg #EAACI #Allergy_journal

Open Access: Effect of venom immunotherapy and sting challenge on HRQoL measured by venom-allergy quality of life questionnaire (VQLQ) in Jack jumper ant allergic patients. Kymble Spriggs, Elizabeth Leahy, Nicole Weibel, Sara Barnes Read the article here: https://lnkd.in/d3kg9V6Z Spriggs et al. report the findings of a questionnaire given to patients allergic to Jack-Jumper Ants before and after receiving 12 months of venom immunotherapy on their health-related quality-of-life (HRQoL). #Allergy_journal Read more articles published in #Allergy on #immunotherapy here: https://lnkd.in/dVsjXuR8

#WorldMentalHealthDay 10th of October 2024 As part of mental health day, we would like to bring awareness to allergic diseases that can coexist with mental health comorbidities. These can be further aggravated by the anxiety related to the disease. The psychosocial impact of allergies is discussed in these recently published articles: 1. Knibb RC, Herbert LJ, Jones CJ, et al. Global availability and uptake of #psychological services for adults, caregivers and children with food allergy. Allergy. 2024;n/a(n/a). doi.org/10.1111/all.16204 2. Cameron S, Donnelly A, Broderick C, et al. Mind and skin: Exploring the links between inflammation, sleep disturbance and neurocognitive function in patients with atopic dermatitis. Allergy. 2024;79(1):26-36. doi.org/10.1111/all.15818 3. Tsai SY, Gaffin JM, Hawryluk EB, et al. Evaluation of dupilumab on the disease burden in children and adolescents with atopic dermatitis: A population-based cohort study. Allergy. 2024;n/a(n/a). doi.org/10.1111/all.16265 4. Piontek K, Ittermann T, Arnold A, Volzke H, Baumeister SE, Apfelbacher C. Prevalence, atopic and psychological comorbidity of physician-diagnosed atopic dermatitis in an adult general population sample: A cross-sectional study. Allergy. 2022;77(6):1915-1917. doi.org/10.1111/all.15288 5. Nemet S, Mahlab-Guri K, Elbirt D, et al. Food allergy is associated with increased risk of developing psychological disorders: A nationwide study of 603,257 Israelis. Allergy. 2023;78(9):2553-2555. doi.org/10.1111/all.15775 6. Eyice Karabacak D, Demir S, Yegit OO, et al. Impact of anxiety, stress and depression related to COVID-19 pandemic on the course of hereditary angioedema with C1-inhibitor deficiency. Allergy. 2021;76(8):2535-2543. doi.org/10.1111/all.14796 7. Lins de Holanda Coelho G, DunnGalvin A, Greenhawt M, et al. Psychometric parameters of food allergy quality of life during an allergen immunotherapy trial. Allergy. 2022;77(9):2770-2777. doi.org/10.1111/all.15323 8. Proctor KB, Tison K, H HE, et al. A systematic review of parent report measures assessing the psychosocial impact of food allergy on patients and families. Allergy. 2022;77(5):1347-1359. doi.org/10.1111/all.15140 Read recent papers published in #Allergy here: journalallergy.com/ #Allergy_journal

Check out this month’s selection of articles by Allergy’s Editor-in-Chief, Cezmi Akdis: 1.     Therapeutic relevance of eosinophilic inflammation and airway viral interactions in severe asthma. Allergy. 2024;79:2589–2604.   doi.org/10.1111/all.16242   2.     Navigating the evolving landscape of atopic dermatitis: Challenges and future opportunities: The 4th Davos declaration. Allergy. 2024;79:2605–2624. doi.org/10.1111/all.16247   3.     IgE glycosylation and impact on structure and function: A systematic review. Allergy. 2024;79:2625–2661. doi.org/10.1111/all.16259   4.     Interleukin-5 as a pleiotropic cytokine orchestrating airway type 2 inflammation: Effects on and beyond eosinophils. Allergy. 2024;79:2662–2679. doi.org/10.1111/all.16303   5.     Allergic inflammation triggers dyslipidemia via IgG signalling. Allergy. 2024;79:2680–2699. doi.org/10.1111/all.16187   6.     Two-year post-treatment outcomes following peanut oral #immunotherapy in the Probiotic and Peanut Oral Immunotherapy-003 Long-Term ( PPOIT - 003LT ) study. Allergy. 2024;79:2759–2774. doi.org/10.1111/all.16262   7.     #Biomarkers of peanut allergy in children over time. Allergy. 2024;79:2775–2786. . doi.org/10.1111/all.16193   8.     IL -10-modulated dendritic cells from birch pollen- and hazelnut-allergic patients facilitate Treg-mediated allergen-specific and cross-reactive tolerance. Allergy. 2024;79:2826–2839. doi.org/10.1111/all.16255     #Allergy_journal Read all recent papers published in Allergy here: journalallergy.com  

Hilal Demir from the Medical University of Vienna, Austria, presents their research findings published in Allergy: Demir H, Radauer C, Strobl MR, Scheurer S, Kinaciyan T, Bohle B. Cross-protection of AIT-induced antibodies to related allergens requires a high degree of structural identity. #Allergy. 2024; Read the article here: doi.org/10.1111/all.16323 https://lnkd.in/d2emf2Et #Allergy_journal Watch videos of recent discoveries: journalallergy.com and youtube.com/@Allergy-TV

Allergy provides the readers with 21 free and open access articles in the October issue! Check out the articles and download freely with one click on the doi link. 1. Rupani H, Busse WW, Howarth PH, et al. Therapeutic relevance of eosinophilic inflammation and airway viral interactions in severe asthma. doi.org/10.1111/all.16242 2. Traidl-Hoffmann C, Afghani J, Akdis C, et al. Navigating the evolving landscape of atopic dermatitis: Challenges and future opportunities: The 4th Davos declaration. doi.org/10.1111/all.16247 3. McCraw AJ, Palhares LCGF, Hendel JL, et al. IgE glycosylation and impact on structure and function: A systematic review. doi.org/10.1111/all.16259 4. Buchheit KM, Shaw D, Chupp G, et al. Interleukin-5 as a pleiotropic cytokine orchestrating airway type 2 inflammation: Effects on and beyond eosinophils. doi.org/10.1111/all.16303 5. Fernández-Gallego N, Castillo-González R, Moreno-Serna L, et al. Allergic inflammation triggers dyslipidemia via IgG signalling. doi.org/10.1111/all.16187 6. Denton E, Hew M, Peters MJ, et al. Real-world biologics response and super-response in the International Severe Asthma Registry cohort. doi.org/10.1111/all.16178 7. Perret JL, Idrose NS, Walters EH, et al. Childhood infections, asthma and allergy trajectories, and chronic rhinosinusitis in middle age: A prospective cohort study across six decades. doi.org/10.1111/all.16184 8. Loke P, Wang X, Lloyd M, et al. Two-year post-treatment outcomes following peanut oral immunotherapy in the Probiotic and Peanut Oral Immunotherapy-003 Long-Term (PPOIT-003LT) study. doi.org/10.1111/all.16262 9. Foong R-X, Du Toit G, van Ree R, et al. Biomarkers of peanut allergy in children over time. doi.org/10.1111/all.16193 10. Knibb RC, Herbert LJ, Jones CJ, et al. Global availability and uptake of psychological services for adults, caregivers and children with food allergy. doi.org/10.1111/all.16204 11. Hiremath G, Choksi Y, Correa H, et al. Children with eosinophilic esophagitis non-responsive to combination therapy have distinct esophageal transcriptomic and microbiome profile. doi.org/10.1111/all.16208 12. Heinl PV, Graulich E, Weigmann B, et al. IL-10-modulated dendritic cells from birch pollen- and hazelnut-allergic patients facilitate Treg-mediated allergen-specific and cross-reactive tolerance. doi.org/10.1111/all.16255 13. Stölzl, D., Sander, N., Siegels, D., et al. Clinical and molecular response to dupilumab treatment in pediatric atopic #dermatitis: Results of the German TREATkids registry. doi.org/10.1111/all.16147 14. Tan, J., Potier-Villette, C., Ni, D., Hoeckh, M., Taitz, J., Simpson, S.J., Nanan, R. and Macia, L. Succinate induces a Th2 environment in the small intestine but does not exacerbate #foodallergy. doi.org/10.1111/all.16155 #Allergy_journal Read all recent papers published in #Allergy here: journalallergy.com

Alessandro Fiocchi from the Pediatric Hospital Bambino Gesu IRCCS, Rome, Italy, presents their research article published in Allergy: Arasi S, Cafarotti A, Galletta F, et al. #Omalizumab reduces anaphylactic reactions and allows food introduction in food-allergic in children with severe #asthma: An observational study. Allergy. 2024; Read the article here: doi.org/10.1111/all.16314 #Allergy_journal Watch videos of recent discoveries: journalallergy.com and youtube.com/@Allergy-TV https://lnkd.in/dXrzwwy3