Allergy EAACI

Exciting News! We are thrilled to announce that Allergy has again achieved the third time the highest impact factor in allergy area ranking us as the 1 journal in the discipline of #Allergy and Clinical #Immunology. We want to extend our deepest gratitude to everyone who contributed to this success. Your commitment to excellence has made this possible. Thank you for being part of our journey towards advancing science. #Allergy_journal journalallergy.com

🚨 The #EAACI Congress 2024 abstracts are now live online! 🚨 Explore groundbreaking research in allergy and clinical immunology with topics ranging from Aerobiology and Food Allergy to AI in healthcare, Environmental Allergies & Climate Change, Microbiome, Pediatrics, and more. With 251 oral abstracts, 325 flash talks, and 760 thematic posters. 🔗 Check it out here: https://lnkd.in/dcrpHGac #Allergy_journal #EAACI2024 journalallergy.com

Comparison of social network engagement performance between artificial intelligence-generated content and human experts: A study in the field of #immunology and #allergology. Corresponding author: Stefano Palazzo Read the article here: doi.org/10.1111/all.16331 This study compares the performance of social media posts created by humans to those generated using AI, within the field of allergy and immunology, focusing on accounts reached, impressions, accounts engaged and number of likes. Read more articles published in #Allergy here: https://lnkd.in/dz8cXUFd #Allergy_journal

📢One of the most appreciated/liked articles in the social media of Allergy published in 2023: Open Access: #Biomarkers of immediate drug hypersensitivity. First and corresponding authors: Cristobalina Mayorga, Adriana Ariza Read for free here:  https://lnkd.in/e9UxGJqQ Immediate drug hypersensitivity reactions (IDHRs) are overdiagnosed as only a small portion of patients are confirmed allergic after workup. Identification of biomarkers for the diagnosis of IDHRs will facilitate a personalized diagnosis and treatment. This review article with over 130 references discusses mechanisms of drug-induced hypersensitivity, biomarkers in IgE- and IgG-mediated reactions, biomarkers in cytokine release reactions, biomarkers in MRGPRX2-mediated reactions, biomarkers in nonsteroidal anti-inflammatory drugs (NSAIDs) cross-hypersensitivity, biomarkers in Bradykinin-mediated #angioedema. Watch the video abstract prepared by the authors here:  https://lnkd.in/dNsVCp8W #Allergy_journal Read more review articles published in #Allergy here: https://lnkd.in/deQYhS4T

Low mannose-binding lectin levels is associated with aspirin unresponsiveness in aspirin-exacerbated respiratory disease Corresponding author: Blanka Kaplan Read the article here: doi.org/10.1111/all.16329 Long-term high-dose aspirin therapy after desensitization (ATAD) is a common treatment for aspirin-exacerbated/nonsteroidal anti-inflammatory-exacerbated respiratory disease (NSAID-ERD). However, some NSAID-ERD patients do not respond to treatment from ATAD. In this retrospective study, Kaplan et al. identified low mannose-binding lectin levels as a factor associated with #ATAD responsiveness. Read more articles published in #Allergy on drug hypersensitivity here: https://lnkd.in/gfs_z4g6 #Allergy_journal

Cross-protection of AIT-induced antibodies to related allergens requires a high degree of structural identity. First author: Hilal Demir; corresponding author: Barbara Bohle Read the article here: doi.org/10.1111/all.16323 Pru av 1 and Cor a 1.04 served to immunologically characterize IgG induced by sublingual immunotherapy (SLIT) with rMal d 1 or rBet v 1. Pru av 1 is more identical to Mal d 1 than to Bet v 1, the identity of Cor a 1.04 to both allergens is comparable. Either SLIT induced cross-reactive IgG, only rMal d 1-SLIT-induced IgG blocked IgE-binding to Pru av 1. Cross-blocking correlated with stronger binding-force and higher surface identity of allergens. #Allergy_journal Read more articles published in #Allergy on allergen #immunotherapy here: https://lnkd.in/dVsjXuR8

📢 One of the most appreciated/liked articles in the social media of Allergy published in 2023: Open Access: Hot topics in allergen immunotherapy, 2023: Current status and future perspective. First author: Magdalena Zemelka-Wiacek; corresponding author: Marek Jutel Read the article here: https://lnkd.in/efDy8ajE This is a comprehensive review article with over 200 references on recent advances in allergen #immunotherapy (#AIT). It includes a discussion on mechanisms of tolerance of AIT, novel patient enrolment strategies, new methodology for clinical research, methods in AIT development programs, current standards and future needs, advanced data management: big data and artificial intelligence, cost-effectiveness, advances in AIT compound technology, AIT for allergic asthma, and challenges, gaps and future directions. #Allergy_journal Read more review articles published in #Allergy here: https://lnkd.in/deQYhS4T

Global burden of vaccine-associated angioedema and their related vaccines, 1967–2023: Findings from the global pharmacovigilance database. First authors: Yi Deun Jeong, Kyeongmin Lee; corresponding authors: Hayeon Lee, Dong Keon Yon Read the article here: doi.org/10.1111/all.16304 Jeong and Lee et al. investigate the prevalence of vaccine-associated #angioedema with and without #urticaria using data from the international pharmacovigilance database Vigibase across 156 countries from 1967 to 2023. #Allergy_journal Read more articles published in #Allergy on epidemiology: https://lnkd.in/eMT6rxtD

📢One of the most appreciated/liked articles in the social media of Allergy published in 2023: Laundry detergents and surfactants induced eosinophilic airway inflammation by increasing IL-33 expression and activating ILC2s. First author: Kyoko Saito; corresponding authors: Kenji Matsumoto, Cezmi Akdis, Hideaki Morita Read the article here: doi.org/10.1111/all.15762 The administered #laundrydetergents and #surfactants induced eosinophilic airway inflammation accompanied by increased IL-33 expression and activation of IL-5 and IL-13 making ILC2s. Detergent-induced IL-33 expression in the airways was attenuated by an antioxidant (NAC). Detergent residues were detected in all the tested dust extracts collected from homes. #Allergy_journal Read more articles published in #Allergy on asthma here:  https://lnkd.in/dCVQJRc

Transcriptomics in allergy–statistical recommendations. Corresponding author: Michał Ordak Read the article here: doi.org/10.1111/all.16306 Ordak et al. provide recommendations for the statistical analysis of transcriptomic data in the context of allergies. It includes a discussion on the importance of data normalization, the use of advanced statistical models, methods for dimensionality reduction and feature selection, testing thousands of genes to increase the statistical power and recommended machine learning approaches. #Allergy_journal Read more articles published in #Allergy on #genetics here: https://lnkd.in/eMT6rxtD