Bioengineering MDPI

🔬 Excited to share the publication "Effects of Extreme Temperature on Human Bronchial Epithelial Cells in 3D Printed Samples". 🥼 Authored by Taieba Tuba Rahman, Nathan Wood, Zhijian Pei and Hongmin Qin 🚀 This paper reports an experimental study on the effects of extreme temperature on human bronchial epithelial (HBE) cells encapsulated in 3D printed samples. This research can potentially advance the knowledge regarding effects of heat exposure on the respiratory system. Welcome to access the full article freely here 👉 https://lnkd.in/gWwxkb2s. And welcome to follow our LinkedIn account: https://lnkd.in/grPNkBrg. 👏 #3D_printing #cell_viability #extreme_temperature #bronchial #epithelial_cells #mitochondrial_oxidative_stress

🔬 Excited to share the publication "Raman Handheld Versus Microscopic Spectroscopy for Estimating the Post-Mortem Interval of Human Bones: A Comparative Pilot Study". 🥼 Authored by Johannes Dominikus Pallua, Christina Louis, Nicole Gattermair, Andrea Brunner, Bettina Zelger, Michael Schirmer, Jovan Badzoka, Christoph Kappacher, Christian Wolfgang Huck, Jürgen Popp, Walter Rabl and Claudia Wöss. 🚀 The post-mortem interval estimation for human skeletal remains is critical in forensic medicine. This study used Raman spectroscopy, specifically comparing a handheld device to a Raman microscope for PMI estimations. Welcome to access the full article freely here 👉 https://lnkd.in/g5WN56Dy. #skeletal #post_mortem_interval #Rama #principal_component_analyses

🔬 Excited to share the publication "Building an Ethical and Trustworthy Biomedical AI Ecosystem for the Translational and Clinical Integration of Foundation Models". 🥼 Authored by Baradwaj Simha Sankar, Destiny Gilliland, Jack Rincon, Henning Hermjakob, Yu Yan, Irsyad Adam, Gwyneth Lemaster, Dean Wang, Karol Watson, Alex Bui, Wei Wang and Peipei Ping. 🚀 Foundation Models (FMs) are gaining increasing attention in the biomedical artificial intelligence (AI) ecosystem due to their ability to represent and contextualize multimodal biomedical data. These capabilities make FMs a valuable tool for a variety of tasks, including biomedical reasoning, hypothesis generation, and interpreting complex imaging data. This review addresses the unique challenges associated with establishing an ethical and trustworthy biomedical AI ecosystem, with a particular focus on the development of FMs and their downstream applications. Welcome to access the full article freely here 👉 https://lnkd.in/gaxZUjJ2. And welcome to follow our LinkedIn account: https://lnkd.in/grPNkBrg. 👏 #biomedical #AI #Foundation_Models #lifecyle #clinical #trustworthy #governance #regulation #stakeholder

🔬 Excited to share the publication "PRF Lysates Modulate Chemokine Expression in Oral Squamous Carcinoma and Healthy Epithelial Cells". 🥼 Authored by Zohreh Afradi, Layla Panahipour, Salman Abbas Zadeh and Reinhard Gruber. 🚀 Platelet-rich fibrin (PRF), originally used to support soft tissue healing, is also considered a therapeutic option for treating oral lichen planus and leukoplakia. The findings in this study suggest that PRF may reduce inflammation in a malignant environment while provoking an immunological response in healthy oral epithelium. Welcome to access the full article freely here 👉 https://lnkd.in/gBdWAQJf. And welcome to follow our LinkedIn account: https://lnkd.in/grPNkBrg. 👏 #platelet #fibrin #PRF #oral #carcinoma #HSC2 #TR146 #oral_epithelial_cells #chemokines #inflammation

♻️ Our new article, "A Microbial-Centric View of Mobile Phones: Enhancing the Technological Feasibility of Biotechnological Recovery of Critical Metals", has just been published in Bioengineering MDPI. Access it here 👉 https://lnkd.in/exFjQEmG 🔬 In this work, we dive deep into the untapped potential of #microbial diversity in revolutionizing the recycling of mobile phones. Our study offers a fresh perspective on #biohydrometallurgy and emphasizes the need for ecodesign in electronics to make #recycling processes more effective and sustainable. 🦠 It’s inspiring to realise that #nature hold the key to solving one of the biggest environmental challenges we face today: #electronicwaste. Thanks to the colleagues ILARIA BASSANI, Francesca Verga, Fabrizio PIRRI that participated to this nice work. A huge thank to my colleague Chiara Magrini who started this scientific journey with me embracing every challenge along the way. This work is part of the iENTRANCE@ENL initiative, supported by the European Union – NextGenerationEU under the National Recovery and Resilience Plan (NRRP). Let’s keep research driving circularity forward! #Ewaste #Sustainability #Bioleaching #CircularEconomy #GreenInnovation #ElectronicWaste #ResearchImpact

🔬 Excited to share the publication "Verification and Validation of Advanced Control Systems for a Spinal Joint Wear Simulator". 🥼 Authored by Kaushikk Ravender Iyer, David Keeling and Richard M. Hall. 🚀 Wear simulation aims to assess wear rates and their dependence on factors like load, kinematics, temperature, and implant orientation. Despite its significance, there is a notable gap in research concerning advancements in simulator control systems and the testing of clinically relevant waveforms. This study addresses this gap by focusing on enhancing the conventional proportional–integral–derivative (PID) controller used in joint simulators through the development of a fuzzy logic-based controller. Welcome to access the full article freely here 👉 https://lnkd.in/gTVem__F. And welcome to follow our LinkedIn account: https://lnkd.in/grPNkBrg. 👏 #controller #spinal #hardware #simulation #activities

🔬 Excited to share the publication "Comparison of Left Ventricular Function Derived from Subject-Specific Inverse Finite Element Modeling Based on 3D ECHO and Magnetic Resonance Images". 🥼 Authored by Lei Fan, Jenny S. Choy, Chenghan Cai, Shawn D. Teague, Julius Guccione, Lik Chuan Lee and Ghassan S. Kassab. 🚀 This study developed a subject-specific inverse FE model based on 3D ECHO and MR images acquired from seven healthy swine models to investigate if there are differences in myocardial contractility and LV geometrical features derived using these two imaging modalities. Welcome to access the full article freely here 👉 https://lnkd.in/gt9jYs7B. And welcome to follow our LinkedIn account: https://lnkd.in/grPNkBrg. 👏 #3D_ECHO #magnetic_resonance_image #MRI #ventricular #mechanics #computational_modeling #myocardial_contractility

🔬 Excited to share the publication "Functional and Molecular Analysis of Human Osteoarthritic Chondrocytes Treated with Bone Marrow-Derived MSC-EVs". 🥼 Authored by Annachiara Scalzone, Clara Sanjurjo-Rodríguez, Rolando Berlinguer-Palmini, Anne M. Dickinson, Elena Jones, Xiao-Nong Wang and Rachel E. Crossland. 🚀 Osteoarthritis (OA) is a degenerative joint disease, causing impaired mobility. the data provide new insights on the potential mechanism of action of MSC-EVs as a treatment option for early-stage OA, including transcriptomic analysis of MSC-EV-treated OA, which may pave the way for more targeted novel therapeutics. Welcome to access the full article freely here 👉 https://lnkd.in/gMxuNbRb. And welcome to follow our LinkedIn account: https://lnkd.in/grPNkBrg. 👏 #extracellular_vesicles #mesenchymal_stromal_cell #chondrocyte #osteoarthritis #regenerative_medicine

🔬 Excited to share the publication "Chitosan Scaffolds from Crustacean and Fungal Sources: A Comparative Study for Bone-Tissue-Engineering Applications". 🥼 Authored by Neelam Iqbal, Payal Ganguly, Lemiha Yildizbakan, El Mostafa Raif, Elena Jones, Peter V. Giannoudis and Animesh Jha. 🚀 Chitosan (CS), a biopolymer, holds significant potential in bone regeneration due to its biocompatibility and biodegradability attributes. The data suggest that MDC scaffolds could be a potent alternative to ADC-derived scaffolds for bone regeneration applications, particularly for 10(wt)% TCP concentrations. Welcome to access the full article freely here 👉 https://lnkd.in/guRSVgYv. And welcome to follow our LinkedIn account: https://lnkd.in/grPNkBrg. 👏 #fungal #crustacean #chitosan #bone_regeneration #tissue_engineering

📢 A new Special Issue "Stem Cell Engineering and Tissue Regeneration" is now open for submissions! 🥼 This Special Issue is co-guest edited by Dr. Bo Wang and Dr. Shue Wang. This Special Issue focuses on the latest advances in stem cells and tissue engineering, highlighting their role in regenerative medicine. Topics of interest include: 💡 Stem cell research: pluripotent, mesenchymal, and reprogrammed stem cells; organoids; and genetic engineering. 💡 Tissue engineering: bioengineered tissues, 3D printing, nanomaterials, and hybrid constructs. 💡 Biomaterials and delivery systems: smart scaffolds, hydrogels, and controlled release systems. 💡 Clinical translation: preclinical/clinical studies, vascularization, immune response, and commercialization. 💡 Mechanistic insights: cell–matrix interactions, omics, and computational modeling. 🔗 Click the link to access more details about the Special Issue: https://lnkd.in/ggDHqJGv 🕑 The deadline for manuscript submissions is 1 November 2025. 🎉 Welcome to join us as authors and reviewers! #StemCell #Engineering #Tissue_Regeneration