Biomedicines MDPI

#HighlyCitedPapers   📝 Dynamics of Gene Expression Profiling and Identification of High-Risk Patients for Severe COVID-19 — Rombauts, et al.   In this paper, the authors aimed to determine the dynamic transcriptomic profile of adult patients hospitalized for COVID-19 and to characterize the subgroup that developed severe disease and acute respiratory distress syndrome.   Full text is available 👇 https://lnkd.in/dq3MbiSt   #medicine #health #research #science

#ParticularInterestPaper   📝 Different Effects of Valproic Acid on SLC12A2, SLC12A5 and SLC5A8 Gene Expression in Pediatric Glioblastoma Cells as an Approach to Personalised Therapy — Damanskienė, et al.   In this paper, the authors aimed to investigate if there are differences in VPA’s effect on the expression of NKCC1, KCC2 and SLC5A8 co-transporter genes between high-grade SF8628 cells and high-grade PBT24 cells.   Full text is available 👇 https://lnkd.in/d4P9FDNR   #medicine #health #research #science

#HighlyCitedPapers   📝 Towards a Procedure-Optimised Steerable Catheter for Deep-Seated Neurosurgery — Aktas, et al.   In this paper, the authors aimed to demonstrate a new manufacturing method for programmable bevel-tip needles that employs thermal drawing technology.   Full text is available 👇 https://lnkd.in/dv4GCcqg   #medicine #health #research #science

#ParticularInterestPaper   📝 The Potential Important Role of Mitochondrial Rieske Iron–Sulfur Protein as a Novel Therapeutic Target for Pulmonary Hypertension in Chronic Obstructive Pulmonary Disease — Truong, et al.   In this paper, the authors aimed to highlight the recent findings on the roles of altered mitochondrial bioenergetics in pulmonary hypertension in chronic obstructive pulmonary disease.   Full text is available 👇 https://lnkd.in/dPeF8r64   #medicine #health #research #science

#HighlyCitedPapers   📝 Apabetalone Downregulates Fibrotic, Inflammatory and Calcific Processes in Renal Mesangial Cells and Patients with Renal Impairment — Gilham, et al.   In this paper, the authors aimed to investigate the effectiveness of apabetalone, in reducing the risk of chronic kidney disease-related major adverse cardiac events.   Full text is available 👇 https://lnkd.in/ddVv-vY4   #medicine #health #research #science

#ParticularInterestPaper   📝 SARS-CoV-2 Infection, Sex-Related Differences, and a Possible Personalized Treatment Approach with Valproic Acid: A Review — Stakišaitis, et al.   In this paper, the authors aimed to evaluate valproic acid (VPA) as a potential medicine for the treatment of COVID-19 and to elucidate the possible biological sex-related mechanisms of pharmacology.   Full text is available 👇 https://lnkd.in/dpZvgM_7   #medicine #health #research #science

#ParticularInterestPaper   📝 Cell Type-Specific Anti-Adhesion Properties of Peritoneal Cell Treatment with Plasma-Activated Media (PAM) — Holl, et al.   In this paper, the authors aimed to provide insights into biochemical plasma-activated media mechanisms which lead to cell type-specific pro-therapeutic cell responses.   Full text is available 👇 https://lnkd.in/d53nsRMd   #medicine #health #research #science

#HighlyCitedPapers   📝 The Role of Selenium in Atherosclerosis Development, Progression, Prevention and Treatment — Dabravolski, et al.   In this paper, the authors focus on the importance of #selenium in cardiovascular health and provide updated information on the role of Se in specific processes involved in the development and pathogenesis of atherosclerosis (oxidative stress, inflammation, endothelial dysfunction, vascular calcification and vascular cell apoptosis).   Full text is available 👇 https://lnkd.in/dMC9Sqeh   #medicine #health #research #science

#ParticularInterestPaper   📝 Diagnostic and Clinical Value of Specific Autoantibodies against Kelch-like 12 Peptide and Nuclear Envelope Proteins in Patients with Primary Biliary Cholangitis — Bauer, Alicja, Andrzej Habior, and Damian Gawel.   In this paper, the authors determined specific antibodies directed against the KLHL12 peptide in sera of Polish primary biliary #cholangitis patients and compared them to autoantibodies against anti-NE proteins, including anti-gp210, anti-p62, and anti-LBR.   Full text is available 👇 https://lnkd.in/dndt87is   #medicine #health #research #science

Chronic kidney disease (CKD) and Alzheimer’s disease (AD) are common chronic diseases in the elderly population. In this paper, the authors aimed to explore the onset of AD and to suggest possible preventive measures for individuals with CKD. 📝 Exploring the Link between Chronic Kidney Disease and Alzheimer’s Disease: A Longitudinal Follow-Up Study Using the Korean National Health Screening Cohort — Kwon, et al. Full text is available 👇 https://lnkd.in/dCz2eu_x #medicine #health #research #science