The Lung Precision Medicine (LPM) program at the DBMR brings together a diverse team of biologists, clinicians, physicists, and engineers from the University of Bern and Insel Gruppe. We are dedicated to advancing precision medicine to address acute and chronic lung diseases, lung regeneration, and connective tissue disorders. Together, we are committed to making a difference in patients' lives. LungHealth#PrecisionMedicine#ResearchCollaboration Meet our dedicated team of experts who are at the forefront of this mission, working tirelessly to push the boundaries of lung health and precision medicine. Thomas Geiser, Alexander Eggel, Matthias V. Kopp, Britta Maurer, Manuela Funke-Chambour, MD, Philipp Latzin, Kerstin Klein, Amiq Gazdhar, Janine Gote-Schniering, Loretta Müller, Emilie Seydoux, Fabian Blank, Tiziana P. Cremona, Seyran Mutlu, Martina Dzepic, Daniel Guggisberg, Nadine Roos, Deepika Anand. Ph.D., Dr Namrata Kewalramani Saxena, Melanie Steinmann, Céline Ferrié, Susan De Groof, Huijuan Wang, Daniel Brigger, Carlos Machahua, Pascal Guntern, Matthias Brunner, Michael Ammeter, Laura J., Lukas Balsiger, Mila Roceri, Anna-Maria Bandian, Julia Rieser, Ekaterina Ivanova, Lisa Blockwitz, Remo Frei, Tinevimbo Baricholo, Jennifer Amsler, David Lauer, Andrea Stokes, Anna-Barbara Tschirren Learn more about our team and research at our website: https://lnkd.in/e-7Y7ZHT.
Lung Precision Medicine (LPM) DBMR Bern
Biotechnologieforschung
Bern, Berne 74 Follower:innen
The LPM Program in Bern unites experts to fight lung diseases and improve lives.
Info
The Lung Precision Medicine (LPM) research program is an interdisciplinary initiative that brings together clinicians, biologists, physicists, and engineers from the University of Bern and the University Hospital of Bern. Our mission is to address unmet clinical needs, focusing on acute and chronic lung diseases, lung regeneration, and connective tissue disorders. We strive to improve existing methods and develop innovative approaches to studying the respiratory system in the laboratory. Our techniques include lung-on-chip models, 3D cell cultures, organoids, and precision-cut lung slices, utilizing patient-derived cells, including induced pluripotent stem cells, to accurately replicate lung conditions and create personalized disease models. Our research seeks to understand the underlying causes of various lung diseases, such as asthma, lung fibrosis, COPD/emphysema, primary ciliary dyskinesia, cystic fibrosis, bronchopulmonary dysplasia, lung cancer, autoimmune lung diseases, and allergies. We explore the organ systems, key cellular mechanisms, and external factors like viruses and air pollutants that contribute to these conditions. Employing a multi-omics approach with human biosamples, we integrate imaging technologies and disease modeling in both animal and in vitro settings. Our ultimate goal is to develop new personalized treatments, including potential direct applications to the lungs. As people age, they are more prone to chronic lung diseases like fibrosis and emphysema due to changes in metabolism, mitochondrial function, DNA damage, inflammation, and other factors that impact cellular and tissue function. We investigate these changes across different patient populations to create tailored treatment strategies. Our laboratory findings are validated using patient samples and clinical studies to ensure their clinical relevance and effectiveness. Our overarching aim is to promote lung health, facilitate healing, and make breathing easier for patients.
- Website
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https://www.dbmr.unibe.ch/research/research_programs/index_eng.html#pane1478777
Externer Link zu Lung Precision Medicine (LPM) DBMR Bern
- Branche
- Biotechnologieforschung
- Größe
- 11–50 Beschäftigte
- Hauptsitz
- Bern, Berne
- Art
- Bildungseinrichtung
- Spezialgebiete
- Biomedicine, Lung Disease und Pulmonary Research
Orte
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Primär
Murtenstrasse 28
Bern, Berne 3008, CH
Updates
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Lung Precision Medicine (LPM) DBMR Bern hat dies direkt geteilt
The Organs-on-Chip Technologies from the ARTORG Center for Biomedical Engineering Research of the University of Bern is hiring! We are looking for a passionate PhD student to develop the next-generation lung-on-chip. We look forward to hearing from you!
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Lung Precision Medicine (LPM) DBMR Bern hat dies direkt geteilt
I am glad to share the details of the upcoming Patient’s Conference organized by the Alpha-1 Europe Alliance and the European Lung Foundation, with the support of EARCO. The event will take place online on November 5th, 2024. This is a great opportunity to connect with experts and the patient community, discussing Alpha-1 Antitrypsin Deficiency and advancements in lung health. Stay tuned for more updates and mark your calendars for this important event! #AATD #raredisease #ERS #ELF #ALPHA1EuropeAlliance #EARCO #Alpha1.ch #awareness #Alpha1PatientConference2024
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Lung Precision Medicine (LPM) DBMR Bern hat dies direkt geteilt
Developing a novel cell-based diagnostic test that performs reliably is no easy task. It requires rigorous validation in a real-world patient cohort, with appropriate controls and blinded assessments. Demonstrating its clinical utility against current state-of-the-art diagnostics with favorable outcomes is the true measure of success. I'm excited to share that we've achieved all of the above with our Hoxb8 mast cell activation test #Hoxb8MAT in our recent study on peanut allergy diagnosis, now published in Allergy EAACI. A big thank you to our collaborators from The Hospital for Sick Children in Toronto, Canada who made this possible! Next steps - to make this exciting test available to clinicians & patients in an #IVDR/ FDA certified manner! #GoalsFor2025 Thomas Eiwegger, Thomas Kaufmann, Julia Upton, Noemi Bachmeier-Zbären, Rosa Robin van Brummelen, Alper Celik, Melanie Steinmann, Nadine Roos, University of Bern, Department for BioMedical Research DBMR, Lung Precision Medicine (LPM) DBMR Bern, The Hospital for Sick Children, ATANIS Biotech AG, Jean-Pierre Kinet, FARE, Innovation Office University of Bern, European Academy of Allergy and Clinical Immunology - EAACI, Rheumatologie_Immunologie Bern
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Lung Precision Medicine (LPM) DBMR Bern hat dies direkt geteilt
Am diesjährigen ISMA-RHINA 2024 (International Symposium on Molecular Allergology, European Rhinallergy Meeting) Kongress der European Academy of Allergy and Clinical Immunology #EAACI in Helsinki konnte Fabio Simon Ryser für sein Poster «The Influence of Dupilumab on the Nasal and Gastrointestinal Microbiome in Diffuse Type 2 Chronic Rhinosinusitis» den Posterpreis der RHINA-Gesellschaft entgegennehmen. Herzliche Gratulation an das ganze Forschungsteam! #Fabio Simon Ryser #Urs Christian Steiner #Joseena Iype #Michael Soyka #Silvio D Brugger #Tina Mauthe #Catrin Brühlmann #inselgruppe #unibern #rheumatologie #immunologie
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🎉 Exciting news from the Lung Precision Medicine Program! Members Fabian Blank, Emilie Seydoux, and Thomas Geiser have received funding from the Lungenliga Schweiz (Swiss Lung Association) to assess the toxicity and impact of micro- and nanoplastics in the lung using advanced in vitro models. This important research will help us better understand the health risks posed by micro- and nanoplastics on the respiratory system. Congratulations to the team! 👏👏 #Microplastics #Nanoplastics #Toxicity #LungResearch #PrecisionMedicine #EnvironmentalHealth #InVitroModels
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Congratulations to LPM member Loretta Müller and her collaborator Benedikt Huber (HFR) on receiving the prestigious #NATVANTAGE grant! 🎉 Their research will focus on investigating the impact of gentiana root extract on ciliary activity using an advanced nasal epithelial cell model. This innovative work has the potential to deepen our understanding of respiratory health and contribute to the development of novel therapeutic strategies. We are proud of their achievement and look forward to the insights this research will bring. Well done, Loretta and Benedikt! #WilhelmDoerenkampStiftung #ResearchInnovation #RespiratoryHealth #Collaboration University of Bern Insel Gruppe
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An intesting opportunity to be a part of our team. Detalis regarding the open PhD position in the link below
Junior Group Leader at Lung Precision Medicine, Bern University Hospital & University of Bern, Switzerland
📢 OPEN PhD POSITION! Looking for a PhD, and interested in the impact of nano- and microplastics on the respiratory tract using sophisticated in vitro models? Apply now to join a collaborative team at the Lung Precision Medicine program of the University of Bern! ✔ Details here:
Uni Bern: PhD (or MD-PhD) studentship
ohws.prospective.ch
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We are thrilled to congratulate Tiziana P. Cremona on securing two prestigious grants! 🎉 One from the Blackswan Foundation for rare diseases research and another from the Lungenliga Bern for advancing pulmonary health. Tiziana's dedication and commitment to research excellence continue to inspire us all. We look forward to seeing the impactful contributions these grants will enable in the fields of rare diseases and pulmonary health. Well done, Tiziana! #ResearchExcellence #RareDiseases #PulmonaryHealth #Innovation #ProudTeamMoment
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Lung Precision Medicine (LPM) DBMR Bern hat dies direkt geteilt
Great ILD state of the art session! Great chairs, co-speakers and audience- thanks to ERS for the opportunity to participate