SUN bioscience

🎧 #PODCAST - Organoids: From Dish to Discovery | In case you missed it! 🧬 Last month, Kimberly Homan was invited ‘to the bar’ on Genentech’s podcast, where she shared how her team uses #Organoids to better predict clinical outcomes. At SUN bioscience, we support Kim’s vision for the future of this exciting field! In the podcast, she does an amazing job explaining #complex science in a way that’s accessible and understandable — even for those who don’t work with organoids! 👩🔬👨🔬 🌟 Catch up on the episode now: http://spr.ly/6044oWwq2 #OrganoidsNews #ScientificPodcast #FutureOfScience

📚 PUBLICATION | Check out this new review highlighting various applications of #Gri3D for #3DCellCultures! 🎆 We are thrilled to see the recent publication titled "iPSC-Derived and Patient-Derived Organoids: Applications and Challenges in Scalability and Reproducibility as Pre-Clinical Models" in Current Research in Toxicology. Part of this outstanding research was conducted using our #Gri3D platform, and we are so proud of the results! A big shoutout to the amazing team at Doppl SA involved: Elisa Heinzelmann, PhD, Francesco Piraino, PhD, Mariana Costa, and the rest of the talented collaborators! 👏 Check out the full article here: https://lnkd.in/ey2CgkKT #Organoids #Gri3D #3DCellCulture #Innovation #Collaboration SUN bioscience

🌍 🇨🇭 | The SUN at UPM Biomedicals 10th Annual Conference It was an incredible experience to witness UPM Biomedicals reach their 10th milestone at today's annual conference in #Basel. The event was filled with inspiring talks that spanned a range of cutting-edge topics—from advancements in medical devices and implants to the future of automated #3D cell culture systems. The entire day focused on the central theme of advancing research toward #AnimalFree solutions. SUN bioscience extends heartfelt thanks to UPM Biomedicals for the invitation and the excellent organization of such a successful event. We can only imagine the immense effort that went into making it happen 💜 Piia Mikkonen, Essi Niemi, Marlies Mürnseer always great to see you! #3DCellCulture #Innovation #Basel #SUNtravel #RightModel #RightQuestion Michelle Ballabio

🌍 🇨🇭 | The SUN at UPM Biomedicals 10th Annual Conference It was an incredible experience to witness UPM Biomedicals reach their 10th milestone at today's annual conference in #Basel. The event was filled with inspiring talks that spanned a range of cutting-edge topics—from advancements in medical devices and implants to the future of automated #3D cell culture systems. The entire day focused on the central theme of advancing research toward #AnimalFree solutions. SUN bioscience extends heartfelt thanks to UPM Biomedicals for the invitation and the excellent organization of such a successful event. We can only imagine the immense effort that went into making it happen 💜 Piia Mikkonen, Essi Niemi, Marlies Mürnseer always great to see you! #3DCellCulture #Innovation #Basel #SUNtravel #RightModel #RightQuestion Michelle Ballabio

🎥 30 Seconds of: ‘What can you do with Gri3D®?’ 📢 This time we’ve challenged Maria Clapés Cabrer to showcase the diverse applications of Gri3D® in just 30 seconds. Here’s her quick overview 🔥! 🌟 Gri3D® is a versatile platform for #3DCellCultures with endless possibilities. From iPSC-derived and adult stem cell organoids to cancer models, spheroids, and assembloids, the potential applications are vast! Discover how Gri3D® can enhance your research across a broad range of applications! Get in touch today at enquiries@sunbioscience.ch. We’re here to support your #3DResearch 💜 #Gri3D #Organoids #Spheroids #HydrogelMicrowells #Applications SUN bioscience

🌐 #Gri3D: One Platform – Endless Possibilities! ✨ Our innovative #Gri3D technology adapts effortlessly to every 3D model, offering unparalleled versatility. From short-term cultures in 200µm small microwells to long-term studies in 1600µm bigger microwells, our SUN bioscience team provides a Gri3D® platform for every application. 🚀 Check out the glimpse of established models in the image! What if your application is not here yet? Contact us to #discuss your projects and our team will advise you. 🔬 Explore the wealth of publications showcasing Gri3D®'s capabilities on our website (https://lnkd.in/ePFUmnhq). Feel free to download the articles and reach out with any questions to enquiries@sunbioscience.ch 📩 #Gri3DInnovation #CellCulture #ResearchAdvancements #organoids #spheroids

📚 PUBLICATION | Pediatric soft-tissue #sarcoma screening in our #Gri3D 600µm microwells ⚡️ Exciting News from SUN bioscience! Our innovative #Gri3D plate takes center stage in groundbreaking research conducted by a collaborative team led by Marie Castets and Laura BROUTIER from Centre Léon Bérard, INSERM, Institut Curie, ADLIN Science, CNRS, and Doppl SA. The teams demonstrated the transformative potential of patient-derived #organoids for ex-vivo drug testing in highly heterogeneous fusion-negative #Rhabdomyosarcoma (FNRMS), a critical pediatric soft-tissue #sarcoma. #Gri3D 600 µm microwells played a pivotal role in miniaturizing the drug screening process, allowing simultaneous #screening on 55 spheres per #RMS #organoid line and per dose of each therapeutic compound, providing a more efficient and high-throughput approach 🔬. The study successfully established stable and expandable FNRMS-derived organoids, overcoming previous #challenges in deriving efficient models with the original tumors' molecular specificities in 3D. These organoids were screened using #Gri3D technology using an image-based high-content assay which enabled simultaneous screening of multiple spheres. These findings underscore FNRMS-derived organoids as powerful tools for drug screening, offering insights into therapeutic responses and resistance prediction. The proof-of-concept approach, focused on apoptosis targeting, opens avenues for innovative drug combinations. At SUN bioscience, we are proud to contribute to advancing research and therapy design through our #Gri3D technology. We look forward to continuing collaborations that push the boundaries of scientific discovery and contribute to improving patient outcomes. 📑 Find the full paper here: https://lnkd.in/dqNEnD3y and contact us at enquiries@sunbioscience.ch to discuss about it! And feel free to contact us if you want to know more (enquiries@sunbioscience.ch). #drugscreening #organoidtechnology #researchinnovation #paper #Gri3Dplate #oncology

❗Don’t miss it! Our first feature on SelectScience® is live! 📝 Explore this special 3D Cell Culture feature, where our #customers and #collaborators highlight various applications on our innovative #Gri3D platform, from beginner-friendly workflows to cutting-edge immuno-oncology assays 🔬 🧬 ⏳ Take 5 minutes to dive in: https://lnkd.in/eq2JXcW6 💬 We’d love to hear your thoughts! If you’re a #Gri3D user, share your feedback by writing a review: https://lnkd.in/erkGH5RH #3DCellFeature #Gri3Dnews #CustomerStories #3Dresearch

📍 POSTER | AI-enabled hit selection on human pancreatic #cancer #organoids grown in #Gri3D 🔬 Measuring the impact of anticancer compounds and their combinations relies heavily on robust ex vivo assays. To this end, patient-derived organoids (#PDOs) are increasingly utilized as effective models for ex vivo testing. In this collaborative work with Molecular Devices and Core Life Analytics, the #Gri3D platform was used to perform #drug #screening on pancreatic #PDOs. Its hydrogel-based microcavities enable the formation of uniform microtissues, all aligned within the same focal plane, making it an ideal choice for high-throughput #screening. Human #pancreatic cancer PDOs were exposed to various anticancer compounds at different doses, and their responses were monitored using the #ImageXpress® system for high-content confocal imaging. 📊 The organoid responses were analyzed with #INCarta® software, and the phenotypic features related to each organoid were further processed with #StratoMineR® software, allowing for robust and unbiased data analysis. This approach demonstrates the potential of #Gri3D technology combined with AI-driven analysis for efficient drug #screening. 📩 Don’t hesitate to contact us (enquiries@sunbioscience.ch) if you want to get your copy, or if you simply want to learn more! 🔍 #Collaboration #PDOs #Screening #Innovative #Hydrogel #Organoids

🎥🎬🎞️ | Step into London's iconic rain with a twist! Enjoy 60 seconds of Science in 3D and a lot of Purple! Dive into ELRIG UK Drug Discovery 2024 with SUN bioscience 💜🔬 #SUNisFUN #SUNtravel #SUNreel #organoids #Gri3D #LondonVibes