都创（上海）医药科技股份有限公司

The BIO-Europe event is just around the corner, and we can't wait to be a part of it! BirdoTech will be showcasing our latest work in biotech, and we're thrilled to have Jie Guo-Thuermann and Edward Davies on the ground to share their insights. Don't forget to schedule a meeting with our team. We're here to listen, share, and collaborate. We're committed to driving innovation forward, and BIO-Europe is a key part of that journey. See you in Stockholm! #BIOEurope2024 #BirdoTech #Innovations #Biotech #Stockholm #DrugDiscovery

On October 19th, the BirdoTech‘s headquarter was abuzz with excitement as we gathered at the Fengxian Little Cabin for our first-ever Fun Sports Day. It was a day filled with spirited competition, team bonding, and a whole lot of fun! As the day wound down, we celebrated our top three teams with a well-deserved awards ceremony. They took home not just trophies but also the admiration of their peers for their dedication and sportsmanship. Every laugh, every drop of sweat, every cheer, and every round of applause will be cherished in our collective Birdo memory bank. Thank you to everyone who made this event a success. Here's to more such moments of joy and teamwork! #BirdoTechFunSportsDay #InfiniteEnergy #TeamSpirit #CorporateWellness

World Polio Day highlights the global efforts to end poliomyelitis (polio) worldwide. Polio is a life-threatening disease caused by the poliovirus, which the World Health Assembly committed to eradicate in 1988. Every year on 24 October, we observe World Polio Day to raise awareness of the importance of polio vaccination to protect every child from this devastating disease, and to celebrate the many parents, professionals and volunteers whose contributions make polio eradication achievable. To ensure a polio-free future for everyone, efforts must continue to maintain high immunization coverage, implement high-quality surveillance to detect any presence of the virus, and prepare to respond in the event of an outbreak. As a company dedicated to using technology for the betterment of society, BirdoTech is committed to raising awareness and contributing to the cause. We're proud to stand with those who are working tirelessly to finish the job. #WorldPolioDay #Innovation #BirdoTech #DrugDiscovery

6-Azabicyclo[3.1.1]heptanes represent a novel class of compounds that act as advanced isosteres of 4-substituted piperidine, which is gaining traction in medicinal chemistry. These bicyclic structures preserve key pharmacological properties of piperidine derivatives while incorporating modifications that may enhance biological activity and selectivity. 𝗦𝘁𝗿𝘂𝗰𝘁𝘂𝗿𝗮𝗹 𝗙𝗲𝗮𝘁𝘂𝗿𝗲𝘀 The 6-azabicyclo[3.1.1]heptane framework features a unique bicyclic arrangement that contributes to its distinctive conformational and steric properties. This bicyclic system consists of a nitrogen atom embedded within a seven-membered ring system, which significantly alters the spatial orientation of substituents compared to traditional piperidine. This structural alteration can improve the compound's interaction with specific biological targets, enhancing potency and reducing off-target effects. 🌟 𝗣𝗼𝘁𝗲𝗻𝘁𝗶𝗮𝗹 𝗔𝗱𝘃𝗮𝗻𝘁𝗮𝗴𝗲𝘀 1. 𝗜𝗺𝗽𝗿𝗼𝘃𝗲𝗱 𝗕𝗶𝗻𝗱𝗶𝗻𝗴 𝗔𝗳𝗳𝗶𝗻𝗶𝘁𝘆: The unique conformation of 6-azabicyclo[3.1.1]heptanes allows for better fit and binding interactions with receptors and enzymes. This can lead to increased efficacy in therapeutic applications. 2. 𝗘𝗻𝗵𝗮𝗻𝗰𝗲𝗱 𝗟𝗶𝗽𝗼𝗽𝗵𝗶𝗹𝗶𝗰𝗶𝘁𝘆: Modifications in the bicyclic structure can influence the lipophilicity of the compounds, which is crucial for their bioavailability and ability to cross biological membranes. 3. 𝗥𝗲𝗱𝘂𝗰𝗲𝗱 𝗧𝗼𝘅𝗶𝗰𝗶𝘁𝘆: By fine-tuning the molecular architecture, these advanced isosteres can exhibit lower toxicity profiles compared to their piperidine counterparts, making them safer options in drug development. Our paltform AbovChem offers a variety of 6-azabicyclo[3.1.1]heptane derivatives. Feel free to reach out to us at marketing@birdotech.com or message our representitive Jie Guo-Thuermann for enquiries. #BicycloHeptanes #BCHP #MedicinalChemistry #BirdoTech #DrugDiscoveryChemistry

From October 8th to 10th, Birdotech had the incredible opportunity to participate in CPHI Milan, one of the premier events in the pharmaceutical industry. Our team was thrilled to connect with industry leaders, researchers, and innovators, showcasing our latest advancements in pharmaceutical chemistry and drug development. 🎉 A heartfelt thank you to everyone who visited our booth and engaged with our team. Your interest and support inspire us to continue pushing the boundaries of what's possible in pharmaceutical science. As we return from Milan, we are energized and ready to implement new ideas and collaborations. Stay tuned for more updates as we continue our mission to revolutionize the pharmaceutical landscape! #CPHIMilan2024 #PharmaceuticalInnovation #Birdotech #Networking #DrugDevelopment #PharmaIndustry

1-Methylimidazole (1-MeIm) is a significant organic compound with a wide range of applications in the pharmaceutical industry, particularly in the development of medicinal drugs with analgesic and anti-inflammatory properties. The role of 1-methylimidazole in medicinal development can be summarized as follows: 🌟 Analgesic and Anti-Inflammatory Agents: 1-Methylimidazole and its derivatives have been found to exhibit potential as analgesic and anti-inflammatory agents. They work by inhibiting the cyclooxygenase (COX) enzymes, which are key in the production of prostaglandins that cause inflammation and pain. 🌟 Inhibition of Inflammatory Mediators: Research has shown that certain imidazole derivatives can effectively reduce the release of pro-inflammatory mediators and inhibit the activity of nuclear factor kappa B (NF-κB), a key transcription factor in the inflammatory response. 🌟 Pharmacophore: The imidazole nucleus is a significant pharmacophore in drug design, with a wide range of biological actions associated with it, including antiarrhythmic, HIV-RT inhibitor, antiulcer, and cytotoxicity properties. This makes it a privileged structure in the development of new medications. The primary methods for introducing 1-methylimidazole in medicinal chemistry are Stille and Suzuki couplings. However, the Suzuki reaction can face challenges due to the electron-rich nature of imidazole. In this context, the Stille reaction is advantageous, providing high stability and tolerance for electron-rich motifs, thus overcoming the limitations of the Suzuki method. Our paltform AbovChem has a large supply of the tin reagent in stock. Feel free to reach out to us at marketing@birdotech.com or message our representitive Jie Guo-Thuermann for enquiries. #1Methylimidazole #DrugDesign #TEADinhibitor #EGFRinhibitor #CDKinhibitor #FerroportinInhibitor #StilleReaction

Our team had a great time during the #SABPA Biopharma Conference. The event fostered insightful discussions about potential collaborations and innovative ideas that could influence the future of the industry. We appreciate the chance to make connections with our friends and we are greatful to all who contributed to the event's success. See you at the next event!

Tomorrow is the big day! We can't wait to welcome you to CPHI Milan 2024. Get ready for a day filled with innovation, collaboration, and Birdotech! #CPHI #DrugDiscovery #MedicinalChemistry #CRO #CDMO #APIintermediates #pharma #healthcare #pharmaceutical #chemical #manufacturing #innovation #biotech #technology #Milan

Get ready for the pharmaceutical industry's biggest event of the year! We're just one week away from CPHI Milan 2024. Don't miss out on the opportunity to connect with industry leaders and explore the latest innovations. See you there! #CPHI #DrugDiscovery #MedicinalChemistry #CRO #CDMO #APIintermediates #pharma #healthcare #pharmaceutical #chemical #manufacturing #innovation #biotech #technology #Milan

We’re excited to announce that BiroTech will be exhibiting at BIO-Europe from November 4-6. Visit our booth to discover our latest innovations in biotechnology and see how we can collaborate to drive the future of healthcare. Let’s explore new possibilities together! Schedule your meeting with our representitives Jie Guo-Thuermann and Edward Davies now, we'll see you in Stockholm soon! #BirdoTech #CRO #Innovation #Pharmaceutical #Collaboration #biotechnology #chemistry #Stockholm