Exploration of Musculoskeletal Diseases

📣 All the articles in the first issue of the EMD journal are now officially online. Welcome to scan and read! 📝 Also, we are always open for your submission. #EMD #rheumatology #Fernando Pérez-Ruiz

💥 New Special Issue Launched Online 💥   📢 Call for Papers ❗ ❗ ❗   🎯 Topic: Innovation in Orthopedics   👨⚕️ Guest Editors: ☑ Prof. Ashok N. Johari, Children’s Orthopaedic Centre, Mumbai, India ☑ Prof. Philippe Hernigou, University Paris, France   📆 Submission Deadline: October 31, 2025   ✅ Scope: This special issue of Exploration of Musculoskeletal Diseases will curate cutting-edge research exploring transformative innovations in orthopedic surgery. Articles related to innovations in the orthopaedic fields of arthroplasty, trauma, spine surgery, orthopaedic device development, implantology and others will form the core of this issue. How have these innovations helped surgeons do a better job? How have these innovations improved the lives of countless patients? What is involved to get an innovation from an idea to the finishing line? What is going to be the future of orthopaedics based on the innovations taking place? Can we peek into the future with a world driven by innovations?   🔎 Learn more about the special issue: https://lnkd.in/gDEaPRHz   ⭐ Keywords: Innovation, orthopaedic technology, orthopaedic education, orthopaedic research, robotic, new implants, 3D printing, cell therapy   🔗 Submission link: https://lnkd.in/gfCMAH-J 📧 Contact editorial office: emd-editorial@explorationpub.com ✒ Author instructions: https://lnkd.in/g7ktcBff

📣 New Commentary Published Online   📑 Bridging the evidence-practice gap for people with gout   ✒ Authors: Mark Russell, James B. Galloway   🎯 Gout is a common and disabling form of arthritis. Despite widely available, highly effective, urate-lowering therapies, such as allopurinol, studies continue to demonstrate poor care for individuals with gout in healthcare systems worldwide. In this commentary, we highlight strategies that can be utilised to overcome real-world barriers to optimal gout care, including allied health professional input, patient and clinician education, self-management strategies, and electronic health record solutions.   ⭐ Keywords: #Gout, #urate-lowering therapy, #allopurinol, #febuxostat, guidelines   🔗 Full article: https://lnkd.in/gKhNEASm 📄 PDF: https://lnkd.in/gnh4W_YM

📢 New Article Published Online 📢   📚 Uricases: reflections on recent developments in the management of challenging gout patients   ✒ Authors: Naomi Schlesinger, Dan Kaufmann   ☑ This review discusses currently approved uricases on the market and some in development; how best to minimize flares, anti-drug antibody (ADA) formation, infusion reactions, and loss of efficacy, and combination with immunomodulation in patients with gout requiring uricase therapy.   ⭐ Keywords: #Gout, #uricase, anti-drug antibodies, infusion reactions, flares   🔗 Read the full article: https://lnkd.in/gFqhsNXg 📑 PDF: https://lnkd.in/g8dZgdeR   🔎 This article belongs to our special issue “Pharmacological and Non-Pharmacological Management of Gout”, edited by Prof. George Nuki. (https://lnkd.in/gqHTkWVG)

📢 New Review Published Online 📢 📚 CPPD—differential diagnostics and differential therapeutic challenges ✒ Authors: Maria L. Voulgari, Herbert Kellner ✅ This review provides a comprehensive overview of CPPD, focusing on its diagnosis, differential diagnosis, therapeutic challenges, and monitoring, with insights into the association between CPPD and cardiovascular risk. Diagnostics in CPPD rely on identifying CPP crystals in synovial fluid or joint tissues, with imaging modalities such as ultrasound and conventional radiography emerging as valuable tools...... 💡 Keywords: #CPPD, calcium pyrophosphate crystal deposition, #chondrocalcinosis 🔗 Read the full article: https://lnkd.in/gzjRKXvN 📑 PDF: https://lnkd.in/g-eUtB2T 🔎 This article belongs to our special issue “Calcium Pyrophosphate Deposition Disease”, edited by Prof. Jürgen Braun. (https://lnkd.in/gvMAkTjq)

📢 New Original Article Published Online 📚 Factors associated with interstitial lung disease in patients with rheumatoid arthritis ✒ Authors: Benyapa Suppa-Udom, Supparerk Disayabutr, Suwimon Wonglaksanapimon, Krittachat Butnian, Wanruchada Katchamart 📧 💡 Interstitial lung disease (ILD) is a significant extra-articular manifestation of rheumatoid arthritis (RA). The prevalence and risk factors for ILD in RA exhibit considerable variation. This study aimed to determine the prevalence and factors associated with ILD in Thai patients with RA. Keywords: #InterstitialLungDisease, #prevalence, #RheumatoidArthritis, #RiskFactors 🔗 Read the full article: https://lnkd.in/g_HHwmkv 📑 PDF: https://lnkd.in/g5UYtfQq

📣 New Perspective Published Online 📰 Selecting the best-value biosimilar in emerging countries ✒ Author: Gilberto Castañeda-Hernández 💡 The aim of biosimilars is to alleviate the financial burden of biological medicinal products. A most relevant challenge for emerging countries is how to select the best option available. In most cases, price is the major determinant, as budgets are chronically scarce. However, initial savings due to price reductions can be overridden if there is a lack of supply due to product shortages or withdrawals. These events can be prevented by a best-value strategy. According to the concept of best-value medicinal products, price is only one of the various criteria to be considered. The purpose of the present paper is to provide suggestions of criteria that can be useful for selecting the best-value biological in emerging countries. Six criteria, that are not limitative, have been selected as follows: standards of regulatory approval, quality of the product, good distribution practices, security of supply, pharmacovigilance, and price. ⭐ Keywords: #Biosimilars, best-value, #emergingcountries, follow-on biologics 🔗 Read the full article: https://lnkd.in/gV6-4HdV 📑 PDF: https://lnkd.in/gwppUEw4 🔎 The article belongs to our special issue "Biosimilars: State of the Art in the Treatment of Rheumatic Diseases", edited by Prof. Valderilio Feijó Azevedo. (https://lnkd.in/gy2BXe3i)

📢 New Original Article Available Online 📢 📝 Nonlinear modification to Hildebrand equation for accelerometry assessment of physical activity: improved accuracy for low activity levels ✒ Authors: Laura A Frey Law ✉ , Shannon L. Merkle, Dana Dailey, Kathleen A. Sluka 💡 Physical activity (PA) is increasingly used as a patient-centered means to treat and/or cope with pain and other symptomology resulting from clinical health conditions. Despite the increasing use of wearable sensors to track PA in healthy and patient cohorts, few algorithms are equally accurate in assessing sedentary and light PA as moderate and vigorous. Given that many older adults and patient cohorts are less active, there is a need for simple algorithms that are easily implemented and valid for the assessment of even low activity levels. Thus, the purpose of this study was to test a simple nonlinear modification to a validated linear algorithm for hip- and wrist-worn accelerometry to measure human PA energy expenditure. ⭐ Keywords: #PhysicalActivity, #ExerciseMonitoring, #ExerciseMeasurement, #RawAccelerometry, #EnergyExpenditure, #LifestylePhysicalActivity, #Actigraphy 🔗 Read the full article: https://lnkd.in/ghxSEacV 📑 PDF: https://lnkd.in/gGkJCBVt

📣 New #SystematicReview Published Online 📣 📚 Role and effectiveness of surface EMG feedback in sports and orthopedic rehabilitation: a systematic review ✒ Authors: Thomas Haab, Peter Leinen, Paul Burkey 💡 The aim of the study was to conduct a literature review within the fields of sports and orthopedic rehabilitation to evaluate the efficacy of interventions incorporating electromyographic feedback (EMG FB) training compared to same interventions without EMG FB. ⭐ Keywords: #Biofeedback, #MuscleActivation, #Myofeedback, #Injury, #Physiotherapy 🔗 Full text: https://lnkd.in/g-J7qDfm 📑 PDF: https://lnkd.in/ggiU5szF

📣 Latest Original Article Published Online 📢 📚 Successful implementation of interchange of biologic medications in chronic arthritis after information of costs to prescribers ✒ Authors: Fernando Perez Ruiz, Elena Garmendia-Sanchez, Javier Arostegui-Lavilla, Javier Duruelo-Echevarrieta, Joana Atxotegi-Saenz de Buruaga, Mayra Nathali Rivas-Zavaleta, Javier Casas-Arrate, Maria del Consuelo Modesto-Caballero, Amaya de Basagoiti-Gorordo ✅ The article aims to evaluate the impact of prescription, cost, and switching policy on the rate of switching from reference products to biosimilars. 💡 Keywords: #Biologics, #Biosimilars, #Interchangeability, #Switching, #Cost 🔗 Read the full article: https://lnkd.in/gpkN_szn 📑 PDF: https://lnkd.in/gbcDp9KE 🔎 This article belongs to our special issue “Biosimilars: State of the Art in the Treatment of Rheumatic Diseases”, guest-edited by Prof. valderilio azevedo. (https://lnkd.in/gy2BXe3i)