HitGen Inc.

The world's leading six international #pharmaceutical companies (AstraZeneca; Bristol Myers Squibb; Johnson and Johnson; Merck & Co., Inc, Rahway, NJ, USA; Pfizer; Roche) have united to establish the pioneering DNA Encoded Library (#DEL) #consortium, with the aim of synergistically harnessing resources and fostering innovative collaboration models to construct DEL libraries more efficiently.  #HitGen, as the exclusive #serviceprovider for the DEL consortium, will leverage our expertise and extensive experience in DEL technology to optimize the construction of DEL libraries, thereby accelerating drug discovery and development. This groundbreaking partnership seeks to expedite the advancement of pharmaceutical innovation and ultimately bestow the benefits upon patients worldwide. 👨🔬 DEL Consortium Members： AstraZeneca; Bristol Myers Squibb; Johnson and Johnson; Merck & Co., Inc, Rahway, NJ, USA; Pfizer; Roche;  DEL Provider: HitGen #DELConsortium

🎉 🎉 The 12th International Symposium on DNA-encoded chemical libraries returns to China, and #HitGen cordially invites you to explore the frontiers of innovation. As a prestigious international academic gathering focusing on cutting-edge technology in the field of DNA-encoded Chemical Libraries (#DEL), the International Symposium on DEL (#ISDEL) was established in 2006 by Professor Dario Neri and Professor Jorg Scheuermann. Since then, it has been held annually in Europe, the United States, and Asia alternately. In 2018, China hosted its first DEL International Symposium successfully in Chengdu, Sichuan. This year marks the return of the 12th DEL International Symposium to China. As an original initiator and organizer of this symposium series, HitGen is dedicated to promoting global development and application of DEL technology. We will actively participate in various aspects of this year's conference. 1️⃣ Expert Face-to-Face Interaction: Our R&D experts from each stage of DEL technology will be present at the event for personal interaction with participants. 2️⃣ Expert Talk: On October 13th from 9:50-10:15 am, Dr. Dou Dengfeng, Vice President of HitGen, will deliver a keynote speech. 3️⃣ Booth Awaits You: Visit us at Booth A04 where we will showcase our latest research findings through 5 posters for discussion. Welcome to register here: https://lnkd.in/gsRXHNx8

I am thrilled to announce that I will be representing HitGen, a global leader in the development and utilization of DNA-Encoded Library (DEL) technology, at the upcoming Discovery on Target conference in Boston. I am eager to deliver a DEL talk on October 1st, and I look forward to connecting with you at the event!

🎤🎤 Our booth at #DoT2024 is No. 512. We eagerly anticipate your visit to our booth, where our team of professional research personnel will be available to address any inquiries you may have. Additionally, #HitGen has thoughtfully prepared distinctive freebies in the hopes of enhancing your DoT experience and ensuring a fruitful and joyful trip with us.

Hi everyone, the 28th #DoT Conference will proceed as planned, and we look forward to meeting you at the venue. If you are interested in revolutionizing your #drugdiscovery process with DNA-encoded libraries (#DEL), please join us for an insightful session on HitGen's disruptive hit identification platform. This technology has the potential to greatly accelerate early-stage small molecule drug discovery. With over 500 DEL clients, #HitGen is a global leader in developing and implementing this innovative approach. Our Vice President, Dr. Alex Shaginian, PhD, MBA, will showcase various successful DEL platforms established at HitGen and share inspiring stories of achievement. We can't wait to see you there! #DoT2024

Macrocycles are generally defined as organic #compounds with a ring of at least 12 atoms and hold in a chemical space between small molecules and biologics. #Infectious disease, #oncology, #autoimmune disorders, and #immunosuppressants are the major therapeutic indications of #macrocyclic #drugs. High-quality of macrocyclic DELs with different ring sizes have been designed and synthesized at #HitGen and this ready-made macrocyclic DELs collection can be directly used for target screening. By integration of parallel #peptide #synthesis, peptide DEL construction and #screening etc., HitGen has established a comprehensive peptide-conjugate platform (PCP). This platform can provide the synthesis of specific amino acids/peptides (used for DEL library design and build), peptide #conjugates synthesis (validation of activity before/after DEL selection), peptide DEL design and construction, DEL selection and high throughput off-DNA synthesis of peptides. The article provides insights into our expertise in macrocycles. If you wish to engage in further discussion, kindly reach out to us via bd@hitgen.com

Cereblon (#CRBN) is an extensively studied #E3 #ligase, widely employed in the development of #PROTACs, #molecular glues, and functionalized tool compounds. In order to facilitate and expedite #protein #degradation discovery and development, we are delighted to offer an all-inclusive collection of CRBN ligands, encompassing nearly all reported variants that are readily available in stock. Moreover, we provide a diverse range of linkers pre-attached to these ligands to accelerate your research. Why Choose Us? 📜 Extensive Inventory: We have a comprehensive stock of nearly all reported CRBN ligands. 👨🔬 Custom Solutions: Diverse linkers connected to CRBN ligands readily available for immediate utilization。 🔬 Flexible Collaboration Models: Both FTE (full-time equivalent) and FFS (fee-for-service) modes are available to suit your project needs. 🤝 Partner up with us to boost your research using top-notch CRBN ligands and intermediates! 📧 Contact us via bd@hitgen.com #HitGen #DEL #E3ligase #drugdiscovery

The feedback we have received from our first Employee Spotlight article has been fantastic! We are thrilled that our audience is enjoying this monthly series. Our next interviewee is Luke Thompson who is a Scientist 1 and joined the Chemistry department at Vernalis in 2020.

Our booth #19 has been exquisitely arranged, adorned with an abundance of adorable pandas and exclusive souvenirs in EFMC-ISMC. Moreover, we have seasoned experts on hand to address any inquiries pertaining to the exciting realm of #drugdiscovery. We extend a warm invitation for you to grace us with your presence! #HitGen #DEL  #nucleicacid 

👨💼 👩💼 Are you working on small molecule or nucleic acid #drugdiscovery in the target validation or hit to lead stage? Learn how DNA-Encoded Library (#DEL) technology can be a vital tool to support your research with the experts at HitGen. You can find #HitGen Inc. in 2024 #EFMC-ISMC, meeting with Mr. Felix Yu, HitGen's executive director of business development! Welcome to stop by No.19 booth!