TowardPi

Double Circulation Pattern in Amelanotic Choroidal Melanoma revealed by 3D full range SS-OCTA! A 54-year-old female patient presented with painless vision loss in her right eye was found a large circular yellowish-white intraocular mass with little pigmentation as shown in the color fundus image (A). Ophthalmic ultrasound showed an intraocular mushroom-shaped choroidal mass with abundant blood flow. MRI revealed corresponding intraocular, oval, T1-isointense, T2-hyperintense mass (C). UWF full range OCTA revealed vascular information in the tumor clearly. A double circulation pattern between retinal and tumor vessels was shown by novel 3D OCTA, corresponding to the result of fluorescein fundus angiography. A diagnosis of amelanotic choroidal melanoma was confirmed by histopathological examination. A 400kHz speed full range swept source OCTA (#BMizar, TowardPi Medical) was used in this case to acquire high-resolution OCTA image of the large intraocular tumor. 3D reconstruction of structure and flow are both available on the device which can provide an insight into the circulation pattern of diseases. This case was published in <Ophthalmology>, authored by Dr. Zhihao Jiang and Dr. Xintong Jiang, team of Prof. Jie Hu, from Zhongshan Ophthalmic Center, Sun Yat-sen University. #ophthalmology #SSOCT #medicaldevices https://lnkd.in/gpqFi2vS

TowardPi Partners with Mainline Instruments for distribution in the UK and Ireland TowardPi Medical is thrilled to announce a new partnership with Mainline Instruments Ltd, a leading provider of high-quality ophthalmic instruments and accessories in the UK and Ireland. This strategic collaboration aims to bring TowardPi's cutting-edge 100-400 kHz Full-Range Swept-Source OCT/OCTA technology to ophthalmologists across the region, enhancing diagnostic and treatment capabilities in ophthalmic care. Established in 1997, Mainline Instruments has built a strong reputation for delivering exceptional service and support to both the optometry and medical communities. With a commitment to offering the latest technological innovations, Mainline ensures that clinics and practices operate efficiently and profitably. Their customer-centric approach and values, such as building enduring relationships and providing honest, long-term service solutions, align perfectly with TowardPi’s mission to improve patient outcomes through advanced medical technology. “We are thrilled to announce our exclusive partnership with TowardPi to introduce their next-generation OCT scanners to the UK and Ireland markets. TowardPi’s OCT technology offers unparalleled speed of capture, depth and width – surpassing anything currently available. Their unique ultrawide angiography scans also represent a significant leap forward in ocular imaging. This collaboration underlines our commitment to market leadership and innovation, ensuring healthcare professionals have access to the most advanced ophthalmic equipment to enhance patient care.” Comments by Mr. Jack Hawkins, the managing director of Mainline Instruments. By combining Mainline Instruments' extensive distribution network and TowardPi’s groundbreaking Swept-Source OCT/OCTA system, eye care professionals in the UK and Ireland will now have access to a powerful diagnostic tool that enables enhanced imaging of the retina, choroid and anterior segment, leading to more accurate and effective treatment of ocular diseases. We look forward to a successful and long-term collaboration with Mainline Instruments as we work together to elevate ophthalmic diagnostics and treatments in the UK and Ireland. Jack Hawkins (Fig L) Managing Director of Mainline Instruments Jian Zhou (Fig R) VP Global of TowardPi Medical at TowardPi Shanghai Global Business Center

“Fireworks” in the fundus revealed by wide field fundus imaging！ A 12-year-old boy presented with distorted vision in his left eye for 3 years was found bilateral, multiple, discrete, round, yellow-white, atrophic, punched-out spots and concentric chorioretinal streaks in the color fundus images (A and B, top). Full range SS-OCTA (#BMizar, TowardPi Medical) images revealed choriocapillaris blood flow defects (A and B, bottom right) corresponding to a typical window defect and scar staining of the lesions in FFA images (A and B, bottom left). Secondary choroidal neovascularization in the left eye (arrowhead) was also detected. Beautiful case report published on JAMA Ophthalmology. This case was authored by Dr. Li Zhang and Dr. Ying-Ying Chen, team of Prof. Mei-Xia Zhang from Sichuan University West China Hospital. #ophthalmology #SSOCT #medicaldevices

Real-time io-OCT in cataract surgery from TowardPi Microscope. Monitoring the entire procedure, from capsulorhexis to IOL implantation. Did you notice the dynamic change of posterior capsule? Say good bye to the limitations of depth and range. The next-gen TowardPi microscope with real-time swept source io-OCT has been commercialized and entered the surgery rooms in China. Stay tuned for more details of this innovative surgical microscope*. *TowardPi microscope is not available for international market yet.

Choroidal indicators for pediatric myopia by UWF full range SS-OCTA! New research recently published on <Photodiagnosis and Photodynamic Therapy> measured the choroidal circulatory parameters in Han Chinese children aged 4–14 years with mild to moderate myopia, and explored the relationships between these parameters and age, axial length (AL), and choroidal thickness (ChT) by using UWF full range SS-OCTA. 3D choroidal circulatory parameters included choroidal vascular volume (CVV), choroidal stromal volume (CSV), choroidal vascularity index (CVI), and CVV/CSV ratio on ultra-wide 24mm x 20mm SS-OCTA of choroid (fig 2). The results showed that both CVV and CSV were found negatively correlated with AL and positively correlated with ChT, while age showed no significant correlation with them. This could be due to developmental increases in CVV and CSV acting as compensatory mechanisms, allowing CVV and CSV to maintain dynamic stability within a certain age range. CVI in children with mild to moderate myopia was unrelated to AL. However, after the age of 8, age was positively correlated with choroidal vascularity index. As age and AL increase, choroidal ChT tends to decrease. And as ChT decreases, both CVV and CSV decrease. Moreover, CVV decreasing more rapidly than CSV. All these findings suggested that changes occurred in the choroid during the process of myopization. “Choroidal circulation parameters are important biological indicators for monitoring the degree of myopia and predicting its progression.” A 400KHz speed full range swept source OCTA (#BMizar, TowardPi Medical) was used in this study to quantify choroid structure and circulatory status base on AI-assisted segmentation algorithm and identification of choroidal vessels (fig 1). The study was authored by Dr. Haoming Geng, team of Prof. Junguo Duan, from Ineye Hospital of Chengdu University of TCM. Link to original text: https://lnkd.in/gXfHR2Ur #ophthalmology #SSOCT #medicaldevices

We celebrate our 7th birthday together🎉 , 330 TowardPi staff, thousands of users and partners all over the world. Share our joy of ceremony in this video: 00:22 Beijing Headquarters; 01:06 Beijing Production Base; 01:19 Shanghai R&D and Global Center; 01:49 Suzhou Production Base; 02:12 Tianjin Production Base; 02:16 Nantong Branch... Crossing the cycle, “π”er’s blossoms🌹 .

The easiest way to compare the OCT performance: SAME eye, SAME disease, SAME scan pattern, and scan at the SAME time, especially for those difficult cases (small pupil, cataract, hemorrhage, high myopia, nystagmus, RD, etc.). Illustrated figure is a case of high elevated retinal detachment with vitreous opacities. Please note the difference in resolution, depth, width, signal/noise ratio. Pictures on the right side, captured by our #Yalkaid in default mode (no further enlarged depth and length). TowardPi swept source OCT is fully CE MDR cleared now. Feel free to contact our global distributors to try and compare with your current devices and see if it worth your new investment.

Retinal Curvature in pediatric myopia, new TowardPi publication in BJO！ New research recently published in <British Journal of Ophthalmology> quantitatively measured retinal curvature (RC) in children with myopia and explored its association with refractive status by using UWF full range SS-OCTA and integrated three-dimensional (3D) reconstruction system on the device. Retinal curvature serves as a brand-new quantitative metric characterizing retina steepness, provides new insights for deeper research into ocular morphology. Using integrated auto-segmentation and retina reconstruction software based on UWF 24mm x 20mm OCTA scan, Bruch’s membrane was identified and isolated. Each point’s Gaussian curvature on Bruch’s membrane was calculated as RC according to axial length (AL) (fig). In this cross-sectional study, Mean RC was assessed in concentric circles (RC I to RC VI) with diameters of 1, 3, 6, 9, 12 and 15 mm around the fovea (fig). The results indicated that the progression of myopia led to a steeper macular retina in children, while the peripheral retina became flatter. Age might be the primary factor driving alterations in retinal morphology, while choroidal thinning also led to a protuberant retina, and axial elongation resulted in the flattening of the peripheral retina. “Retinal curvature, as a novel method for research into ocular morphological abnormalities, offers a convenient means to monitor changes in retinal morphology and potentially provides new insights into disease diagnosis and follow-up care.” A 400kHz speed full range swept source OCTA (#BMizar, TowardPi Medical) was used in this research to assess ocular morphology in 24mm x 20mm ultra-wide field. Retinal curvature based on 3D reconstruction together with structural measurements and flow quantifications are automatically calculated on the device. This research was authored by Dr. Hotin Wu, team of Prof. Xun Xu and Prof. Xiangui He from Shanghai General Hospital and Prof. Li Huo, chief scientist of TowardPi Medical. Link to origin text: https://lnkd.in/gBNsbEkG #ophthalmology #ssoct

The 4 “most diligent distributors” at EURETINA TowardPi booth. The last Episode: OCULUS Brasil Another subsidiary from OCULUS Optikgeräte GmbH - International gets selected, worthy of the reputation of a century-age enterprise. If not Mr. Enrico J. Nitschke, the CEO of Oculus Brasil, we couldn’t have expected so many ophthalmic physicians from Brazil visiting the booth of TowardPi (and Oculus) in a European congress. TowardPi is so pleased and honored meeting prestigious Brazilian ophthalmologists, introducing the latest and best OCT technology to them. Alfa Instruments srl, EBC EUROPE, OCULUS Iberia, OCULUS Brasil. It’s no coincidence that the finalists are all well-known companies. Every harvest comes from every effort. Success or failure depends on details. There’ve been way more than these 4 distributors offered assistance in our exhibition not only in EURETINA but also in ESCRS. We can’t appreciate enough for the efforts and contributions from you. Look forward to the prosperous future together.

Retinal thickness and vessel distribution in 4-to-16-year-old myopic children by using UWF SS-OCTA! This cross-section research recently published in <Photodiagnosis and Photodynamic Therapy> evaluated the characteristics of macular retinal vessel density and thickness in 228 children aged 4-16 years old with myopia by using UWF SS-OCTA. Flow and structural parameters in ETDRS grid including superficial retinal vessel density (SVD), deep retinal vessel density (DVD), inner retinal thickness (IRT), outer retinal thickness (ORT) and full retinal thickness (FRT) (fig. B-G) were analyzed in 24mm x 20mm UWF full range SS-OCTA images (fig. A). subjects were categorized as low myopia group, moderate-to-high myopia group and non-myopia group. This study found that with increasing degree of myopia and AL, the ORT decreases significantly (except for the central fovea) and the fovea and parafovea (except for the inferior region) VD was significantly reduced in the moderate-to-high myopia group. Furthermore, multivariate linear regression analysis adjusting for age and gender showed that the FRT at the fovea was unrelated to AL, while the parafovea and perifovea FRT was negatively correlated with AL and AL was also negatively correlated with DVD in all ETDRS regions. These results indicated that in research focusing on children and adolescents, DVD and ORT were more sensitive to AL than SVD and IRT, suggesting that DVD and ORT may have a more significant correlation with AL growth during myopia progression. A 400kHz full range swept source OCTA (#BMizar, TowardPi Medical) played a crucial role in this study as a simple, non-invasive, and practical technology that allowed for the assessment and quantification of retinal vessel density and retinal thickness at various degrees of myopia. “It also provided clear visualization of some changes in macular retinal vessels and microstructure in children and adolescents, especially the early alterations in the RT and VD associated with myopia.” This study was authored by Dr. Jingyu Mu and Dr. Jing Wei, etc. team of Prof. Junguo Duan and Prof. Juan Wen, from Ineye Hospital of Chengdu University of TCM, China. Link to original text: https://lnkd.in/gJXteJH3 #ophthalmology #ssoct