DIANA Biotechnologies

DB | When unreliable suppliers fail. The story behind our new custom oligonucleotide synthesis in VědaVýzkum.cz "The purity of the supply products was not always optimal, and delivery times often did not meet our needs. Our development required extremely complex oligos—branched, modified, with different dyes or other non-standard modifications. We quickly realized that unless we started producing them ourselves, no one would supply them to us" That's how the article in VědaVýzkum.cz about our oligonucleotide synthesis starts. And that is also one of the first things our Head of Chemistry, Jiri Schimer said during the interview. And what started as an internal necessity has grown into a full-fledged service, offering custom oligonucleotide synthesis for wide range of customers! And what you can get? ✅ TaqMan™ probes, siRNA, LNA-modified oligos ✅ Custom labels with dyes, metal complexes, and advanced modifications ✅ Molecular beacons for cutting-edge diagnostics & research and many more! ⚡DB Oligonucleotide Calculator: The calculator we created is currently the most flexible and user-friendly on the oligonucleotide market. Just enter your desired sequence and modifications and you will get the price and the request immediately. 💡 A customer-first approach We would be more than happy to help you with initial design or project consultation. 📖 Read the full article here: CZ: https://lnkd.in/e3sedCdX EN: https://lnkd.in/eBgibRyA Kudos to: Tereza Mašínová and Kamil Krč #Biotechnology #Oligonucleotides #CustomSynthesis #PCR #Diagnostics #LifeSciences #DIANABiotechnologies #Vedavyzkum

👩🔬 February 11 | International Day of Women and Girls in Science Only 30% of scientists in the Czech Republic are women—one of the lowest rates in the EU. Fortunately, initiatives for gender equality in science have been gaining momentum. However, our company stands out—we’ve consistently had around 60% women in various roles over the past few years. So let's meet them! 🔎 Eva, Life Science: I lead a team focused on developing PCR and RT-PCR chemistries, collaborating with our protein facility on protein development. My role spans product design, production transfer, and quality control, ensuring smooth transitions from R&D to manufacturing. I also provide support across PCR development, balancing hands-on lab work with strategic planning 🧬 Klara, Monoclonal Antibodies Development: My work spans the entire antibody development process—from designing immunization strategies to cloning antibody chains into plasmids. I also manage data analysis and databases, which is increasingly crucial as we take on more commercial projects and develop new antibody clones. 🧪 Gabriela, Diagnostics: As a senior PCR product developer, I focus on quantitative diagnostic kits for herpesviruses. My work is diverse—planning experiments, testing PCR components, optimizing thermal cyclers, and researching nucleic acid stability. I love the variety and the chance to explore different areas of biochemistry. 🔬 Lucia, Drug Discovery: We’re expanding our DIANA Kinase panel, now covering ~150 kinases, with the goal of profiling the entire kinome. In 2024, we introduced our screening services at multiple conferences, receiving great feedback. With our newly established CRO, we provide fast, precise, and cost-effective small-molecule profiling, for wide range of clients. We’re proud to have such talented women shaping the future of our development! Be sure that you will know more of them in the future! 🔥💡 #WomenInScience #InternationalDayOfWomenAndGirlsInScience #DIANABiotechnologies

DIANA Biotechnologies v2025 is finally here, and there’s plenty to look forward to! From an academic spin-off to a diversified biotech company, we proudly introduce the four pillars of DIANA Biotechnologies: 🔵 Diagnostics: The foundation of our growth. https://lnkd.in/eUVKDRfA We developed a unique way to utilize PCR technology without the need for nucleic acid extraction, testing over 6 million samples during the pandemic. Now, we are expanding our solutions to target new areas! 🟠 Life Science: Evolving from our Diagnostics expertise. https://lnkd.in/exCKcGEd We took the best of our IVD PCR products and built a portfolio tailored for molecular biology labs—offering the highest quality and validation. PCR Mixes, RT-PCR Mixes, Enzymes, and even custom oligonucleotide synthesis! With our DBdirect™ and SuperSens technologies, we provide complete solutions for PCR analysis. 🟣 Monoclonal Antibodies: Powered by DIANA technology. https://lnkd.in/eZBqhyf3 We are developing premium rabbit recombinant antibodies, even for the most challenging targets, including small molecules! Our DIANA technology and high-throughput screening (HTS) platform quantitatively rank affinity and cross-reactivity early in development, ensuring the selection of the best plasma cells for monoclonal antibody production. 🔵 Drug Discovery: Where it all began. https://lnkd.in/eRaCsfYZ The DIANA technology is a game-changer for precise and efficient small-molecule screening. With it, we’ve developed the DIANA Kinase Panel and DIANA CDK Panel, enabling the detection of a broad range of kinases. We are thrilled to have you as part of our journey. Rest assured, this is just the beginning—who knows, maybe one or two more segments will emerge by the end of the year. Stay tuned! ⏩ https://lnkd.in/dXRi4rF

🚀 Business Club Meeting at DIANA Biotechnologies! We were delighted to host the Business Club by Středočeské inovační centrum, SIC at our facilities! It was an inspiring gathering of founders and business leaders, where we shared challenges of the private sector in central Bohemia. One of the highlights was an excursion to our laboratories, where we showcased our advanced biotech research and innovation in action. 💡A big thank belongs to SIC and their CEO Pavel Jovanovič and all participants for an engaging discussion. Looking forward to meet again! #DIANABiotechnologies #Biotech

⏩ Superfast Reverse Transcription ⏩ Trying to make your analysis faster? Meet DBscript Reverse Transcriptase and perform your reverse transcription in less than 20 min! ✔️ Superfast Protocol: Achieve reverse transcription in record time – the fastest among top competitors. ✔️ Effortless Workflow: Streamlined steps for primer annealing, incubation, and cDNA synthesis. ✔️ Reliable Results: Exceptional precision and efficiency for demanding molecular biology applications. Whether you're racing against deadlines or optimizing your lab processes, DBscript offers speed and reliability you can count on. Order here (or contact our sales)➡️ https://lnkd.in/ewHq-78n #MolecularBiology #ReverseTranscriptase #CDNASynthesis

🔝 We have passed the United Registrar of Systems (URS) ISO 13845 Audit! We received an early Christmas present: DIANA Biotechnologies has successfully completed the ISO 13485 audit, the global standard for medical device quality management systems! Thank you to all the people in the company, who were participating during the audit. It was a complete teamwork and your help was truly the key to success! Special thanks goes to our Head of QA and RA Eva Filipová and our Head of Production Jakub Hejdánek! It is a proof of our excellent long-term work! ➡️ https://lnkd.in/dXRi4rF

🎄 Christmas at DIANA Biotech! 🎄 The holiday spirit has gradually filled our new building! Before we dive into the joyful whirlwind of Christmas parties and the upcoming calm of the holiday season, we came together to create a little festive magic – a workshop for handmade Christmas candlesticks! A big thank you to Jitka Choteborska and Natálie Brejchová for bringing such a beautiful Christmas atmosphere to life. #Christmas at #DIANABiotech

Genotyping made simple, fast, and completely harmless! 🐀✂️ With Hairotom Technology from AnLab Ltd., a completely non-invasive and painless sampling approach (following the #3R rule), and our cutting-edge DBdirect™ PCR Gel Mix SuperSens, researchers can now perform direct genotyping from rat hair follicles without any nucleic acid extraction. Our latest tests demonstrate the power of this approach: 1️⃣ Hair follicles (collected using #Hairotom, 1/2 of extracted sample) were incubated in Lysis Buffer A (125 μL) at 95°C for 30 minutes. 2️⃣ Crude lysates were used directly in the PCR reaction with no additional purification required. 3️⃣ Results? Clean and reliable amplification, even with minimal tissue input and diluted lysates! Key benefits: 🧬No DNA extraction required – save time and resources. ⏩ Sensitive, efficient and fast – minimal sample input, robust results. 🐭 Completely harmless to the animals – ethical and practical. Check out the attached gel results and protocol to see how simple and effective this system is! ➡️ https://lnkd.in/e_PnydhQ #Genotyping #PCR #MolecularBiology #AnimalResearch #EthicalScience

The DB Headquarters is officially open! ⭐️ The opening ceremony was held by Martin Dienstbier and Václav Navrátil with a special word of prof. Jan Konvalinka, Pavel Brůžek and Zbyněk Halbhuber! Thank you very much! It was an honor to have you as an important part of our ceremony! We have started our journey as a spin-off from Ústav organické chemie a biochemie AV ČR and we became a diversified biotech with four segments of interest: #Diagnostics #LifeScience #MonoclonalAntibodyDevelopment #DrugDiscovery Thank you to all participants and we are looking forward for future cooperation! DIANA Biotechnologies | Diversified Biotech

The very last day of MEDICA - Leading International Trade Fair is ahead of us 🙌 It has been amazing three days full of great talks and new partnerships. Come to see our team and learn more about our diversified biotech DIANA Biotechnologies! Looking forward to see you 🤝 #lifescience #diagnostics #monoclonalantibodies #drugdiscovery #laboratoryinstruments