Computer Methods and Programs in Biomedicine, Volume 226

Volume 226, November 2022

Section IV: Classification and interpretation

• 
  Yuhan Ding, Weifang Xie, Kelvin Kian Loong Wong, Zhifang Liao:
  DE-MRI myocardial fibrosis segmentation and classification model based on multi-scale self-supervision and transformer. 107049
• 
  Weifang Xie, Yuhan Ding, Zhifang Liao, Kelvin Kian Loong Wong:
  Unsupervised domain adaptive myocardial infarction MRI classification diagnostics model based on target domain confused sample resampling. 107055

Section V: Others

• 
  Carlos Sevilla-Salcedo, Vandad Imani, Pablo M. Olmos, Vanessa Gómez-Verdejo, Jussi Tohka:
  Multi-task longitudinal forecasting with missing values on Alzheimer's disease. 107056

Diagnostics and Decision Support

• 
  Iván Sala-Mira, Pedro García, José-Luis Díez, Jorge Bondia:
  Internal model control based module for the elimination of meal and exercise announcements in hybrid artificial pancreas systems. 107061

Section II: Biomedical signal and image processing methods

• 
  Jaesung Yoo, Ilhan Yoo, Ina Youn, Sung-Min Kim, Ri Yu, Kwangsoo Kim, Keewon Kim, Seung-Bo Lee:
  Residual one-dimensional convolutional neural network for neuromuscular disorder classification from needle electromyography signals with explainability. 107079

Section III: Modelling & Simulation

• 
  Fernando Galaz Prieto, Atena Rezaei, Maryam Samavaki, Sampsa Pursiainen:
  L1-norm vs. L2-norm fitting in optimizing focal multi-channel tES stimulation: linear and semidefinite programming vs. weighted least squares. 107084

Section IV: Classification and interpretation

• 
  Zhi-min Zhang, Jian-ping Zhao, Pi-Jing Wei, Chun-Hou Zheng:
  iPromoter-CLA: Identifying promoters and their strength by deep capsule networks with bidirectional long short-term memory. 107087
• 
  Bin Liao, Xiaoyao Jia, Tao Zhang, Ruina Sun:
  DHDIP: An interpretable model for hypertension and hyperlipidemia prediction based on EMR data. 107088

Section II: Biomedical signal and image processing methods

• 
  Lisha Zhong, Jia Wu, Shuling He, Fangji Yi, Chen Zeng, Xi Li, Zhangyong Li, Zhiwei Huang:
  Epileptic seizure prediction in intracranial EEG using critical nucleus based on phase transition. 107091

Section IV: Classification and interpretation

• 
  Qingbin Zhuang, Senzhong Gan, Liangyu Zhang:
  Human-computer interaction based health diagnostics using ResNet34 for tongue image classification. 107096
• 
  Luoyu Lian, Xin Luo, Canyu Pan, Jinlong Huang, Wenshan Hong, Zhendong Xu:
  Lung image segmentation based on DRD U-Net and combined WGAN with Deep Neural Network. 107097

Section V: Others

• 
  Zhiyong Xiao, Yixin Su, Zhaohong Deng, Weidong Zhang:
  Efficient Combination of CNN and Transformer for Dual-Teacher Uncertainty-guided Semi-supervised Medical Image Segmentation. 107099

Section IV: Classification and interpretation

• 
  Jing Zhu, Shiqing Wei, Xiannian Xie, Changlin Yang, Yizhou Li, Xiaowei Li, Bin Hu:
  Content-based multiple evidence fusion on EEG and eye movements for mild depression recognition. 107100

Section II: Biomedical signal and image processing methods

• 
  Dongmei Zhu, Degang Sun, Dongbo Wang:
  Dual attention mechanism network for lung cancer images super-resolution. 107101

Section IV: Classification and interpretation

• 
  Tingting Chen, Bing Xu, Hui Chen, Yuanyuan Sun, Jiahang Song, Xinchen Sun, Xizhi Zhang, Wei Hua:
  Transcription factor NFE2L3 promotes the proliferation of esophageal squamous cell carcinoma cells and causes radiotherapy resistance by regulating IL-6. 107102
• 
  Meng Xing, Yanbo Zhang, Hongmei Yu, Zhenhuan Yang, Xueling Li, Qiong Li, Yanlin Zhao, Zhiqiang Zhao, Yanhong Luo:
  Predict DLBCL patients' recurrence within two years with Gaussian mixture model cluster oversampling and multi-kernel learning. 107103

Section III: Modelling & Simulation

• 
  Weiwei Yu, Dian Jin, Wenfeng Cai, Feng Zhao, Xiaokun Zhang:
  Towards tacit knowledge mining within context: Visual cognitive graph model and eye movement image interpretation. 107107

Diagnostics and Decision Support

• 
  Javier Civit-Masot, Alejandro Bañuls-Beaterio, Manuel Domínguez-Morales, Manuel Rivas Pérez, Luis Muñoz-Saavedra, José María Rodríguez Corral:
  Non-small cell lung cancer diagnosis aid with histopathological images using Explainable Deep Learning techniques. 107108

Section II: Biomedical signal and image processing methods

• 
  Santosh Kumar, Mithilesh Kumar Chaube, Saeed Hamood Alsamhi, Sachin Kumar Gupta, Mohsen Guizani, Raffaele Gravina, Giancarlo Fortino:
  A novel multimodal fusion framework for early diagnosis and accurate classification of COVID-19 patients using X-ray images and speech signal processing techniques. 107109

Section IV: Classification and interpretation

• 
  Xiaolu Zhang, Yiqiang Zheng, Xiaoming Bai, Liquan Cai, Liangming Wang, Shiqiang Wu, Qingfeng Ke, Jianlong Huang:
  Femoral image segmentation based on two-stage convolutional network using 3D-DMFNet and 3D-ResUnet. 107110

Section V: Others

• 
  Guido Rovera, Piero Fariselli, Désirée Deandreis:
  Development of a REDCap-based workflow for high-volume relational data analysis on real-time data in a medical department using open source software. 107111

Diagnostics and Decision Support

• 
  Zhuangzhuang Li, Wenmei Li, Wei Yan, Rongrong Zhang, Shi-Ping Xie:
  Data-driven learning to identify biomarkers in bipolar disorder. 107112
• 
  Bingtao Zhang, Dan Wei, Guanghui Yan, Tao Lei, Haishu Cai, Zhifei Yang:
  Feature-level fusion based on spatial-temporal of pervasive EEG for depression recognition. 107113

Section II: Biomedical signal and image processing methods

• 
  Xinyue Zhang, Hongwei Du, Gang Song, Fangxun Bao, Yunfeng Zhang, Wei Wu, Peide Liu:
  X-ray coronary centerline extraction based on C-UNet and a multifactor reconnection algorithm. 107114

Section I: Biocybernetics and Big Data

• 
  Siwei Bi, Shanshan Chen, Jingyi Li, Jun Gu:
  Machine learning-based prediction of in-hospital mortality for post cardiovascular surgery patients admitting to intensive care unit: a retrospective observational cohort study based on a large multi-center critical care database. 107115

Section II: Biomedical signal and image processing methods

• 
  Didier R. P. R. M. Lustermans, Sina Amirrajab, Mitko Veta, Marcel Breeuwer, Cian M. Scannell:
  Optimized automated cardiac MR scar quantification with GAN-based data augmentation. 107116

Section III: Modelling & Simulation

• 
  Maria Gracka, Rui A. Lima, João Mário Miranda, Sebastian Student, Bartlomiej Melka, Ziemowit Ostrowski:
  Red blood cells tracking and cell-free layer formation in a microchannel with hyperbolic contraction: A CFD model validation. 107117

Section II: Biomedical signal and image processing methods

• 
  Hasitha Wimalarathna, Sangamanatha Ankmnal Veeranna, Chris Allan, Sumit K. Agrawal, Jagath Samarabandu, Hanif M. Ladak, Prudence Allen:
  Machine learning approaches used to analyze auditory evoked responses from the human auditory brainstem: A systematic review. 107118

Section IV: Classification and interpretation

• 
  Matteo Moro, Vito Paolo Pastore, Chiara Tacchino, Paola Durand, Isabella Blanchi, Paolo Moretti, Francesca Odone, Maura Casadio:
  A markerless pipeline to analyze spontaneous movements of preterm infants. 107119

Section V: Others

• 
  Tuomas Karhu, Timo Leppänen, Juha Töyräs, Arie Oksenberg, Sami Myllymaa, Sami Nikkonen:
  ABOSA - Freely available automatic blood oxygen saturation signal analysis software: Structure and validation. 107120

Section III: Modelling & Simulation

• 
  Violeta Monasterio, Esther Pueyo, José Felix Rodriguez Matas, Jesús Carro:
  Cardiac cells stimulated with an axial current-like waveform reproduce electrophysiological properties of tissue fibers. 107121

Section V: Others

• 
  Lucas G. Batista, Pedro Henrique Bugatti, Priscila T. M. Saito:
  Classification of Skin Lesion through Active Learning Strategies. 107122

Section II: Biomedical signal and image processing methods

• 
  Janghoon Ahn, Thong Phi Nguyen, Yoon-Ji Kim, Taeyong Kim, Jonghun Yoon:
  Automated analysis of three-dimensional CBCT images taken in natural head position that combines facial profile processing and multiple deep-learning models. 107123

Diagnostics and Decision Support

• 
  Qinghua Sun, Chunmiao Liang, Tianrui Chen, Bing Ji, Rugang Liu, Lei Wang, Min Tang, Yuguo Chen, Cong Wang:
  Early detection of myocardial ischemia in 12-lead ECG using deterministic learning and ensemble learning. 107124

Section III: Modelling & Simulation

• 
  Rasmus Kuhr Jensen, Mark Clements, Lars Klingen Gjærde, Lasse Hjort Jakobsen:
  Fitting parametric cure models in R using the packages cuRe and rstpm2. 107125

Section II: Biomedical signal and image processing methods

• 
  Hooseok Lee, Heewon Chung, Hoon Ko, Antonino Parisi, Alessandro Busacca, Luca Faes, Riccardo Pernice, Jinseok Lee:
  Adaptive scheduling of acceleration and gyroscope for motion artifact cancelation in photoplethysmography. 107126
• 
  Tae Young Park, Ji Hyeok Jeong, Yong An Chung, Sang Hoon Yeo, Hyungmin Kim:
  Application of subject-specific helmets for the study of human visuomotor behavior using transcranial focused ultrasound: a pilot study. 107127

Diagnostics and Decision Support

• 
  Yunlong Li, Yang Xu, Zuchang Ma, Yuqi Ye, Lisheng Gao, Yining Sun:
  An XGBoost-based model for assessment of aortic stiffness from wrist photoplethysmogram. 107128

Section II: Biomedical signal and image processing methods

• 
  Zhengyong Huang, Sijuan Zou, Guoshuai Wang, Zixiang Chen, Hao Shen, Haiyan Wang, Na Zhang, Lu Zhang, Fan Yang, Haining Wang, Dong Liang, Tianye Niu, Xiaohua Zhu, Zhanli Hu:
  ISA-Net: Improved spatial attention network for PET-CT tumor segmentation. 107129

Section IV: Classification and interpretation

• 
  Hongwei Chen, Sunang Yan, Mingxing Xie, Jianlong Huang:
  Application of cascaded GAN based on CT scan in the diagnosis of aortic dissection. 107130

Section II: Biomedical signal and image processing methods

• 
  Mohammad Bagher Khodabakhshi, Naeem Eslamyeh, Seyede Zohreh Sadredini, Mohammad Ghamari:
  Cuffless blood pressure estimation using chaotic features of photoplethysmograms and parallel convolutional neural network. 107131
• 
  Alice Othmani, Assaad Oussama Zeghina, Muhammad Muzammel:
  A Model of Normality Inspired Deep Learning Framework for Depression Relapse Prediction Using Audiovisual Data. 107132
• 
  Quoc Cuong Ngo, Mohammod Abdul Motin, Nemuel Daniel Pah, Peter Drotár, Peter Kempster, Dinesh K. Kumar:
  Computerized analysis of speech and voice for Parkinson's disease: A systematic review. 107133

Section III: Modelling & Simulation

• 
  Faezeh Moshfeghifar, Torkan Gholamalizadeh, Zachary Ferguson, Teseo Schneider, Michael Bachmann Nielsen, Daniele Panozzo, Sune Darkner, Kenny Erleben:
  LibHip: An open-access hip joint model repository suitable for finite element method simulation. 107140

Section II: Biomedical signal and image processing methods

• 
  Gabriel Iluebe Okolo, Stamos Katsigiannis, Naeem Ramzan:
  IEViT: An enhanced vision transformer architecture for chest X-ray image classification. 107141

Section III: Modelling & Simulation

• 
  Shaoyang Bi, Ziyuan Guo, Xizhong Zhang, Guangyu Shi:
  Anchorage effects of ligation and direct occlusion in orthodontics: A finite element analysis. 107142

Section V: Others

• 
  Christopher Yew Shuen Ang, Jay Wing Wai Lee, Yeong Shiong Chiew, Xin Wang, Chee Pin Tan, Matthew E. Cove, Mohd Basri Mat Nor, Cong Zhou, Thomas Desaive, J. Geoffrey Chase:
  Virtual patient framework for the testing of mechanical ventilation airway pressure and flow settings protocol. 107146

Section II: Biomedical signal and image processing methods

• 
  Ping Xuan, Bin Jiang, Hui Cui, Qiangguo Jin, Peng Cheng, Toshiya Nakaguchi, Tiangang Zhang, Changyang Li, Zhiyu Ning, Menghan Guo, Linlin Wang:
  Convolutional bi-directional learning and spatial enhanced attentions for lung tumor segmentation. 107147

Section III: Modelling & Simulation

• 
  Fernando Escobar, Julio Gomis-Tena, Javier Saiz, Lucía Romero:
  Automatic modeling of dynamic drug-hERG channel interactions using three voltage protocols and machine learning techniques: A simulation study. 107148
• 
  Jingheng Shu, Annan Li, Bingmei Shao, Desmond Y. R. Chong, Jie Yao, Zhan Liu:
  Descriptions of the dynamic joint space of the temporomandibular joint. 107149

Section II: Biomedical signal and image processing methods

• 
  Jiechao Wang, Qinqin Yang, Qizhi Yang, Lina Xu, Congbo Cai, Shuhui Cai:
  Joint optimization of Cartesian sampling patterns and reconstruction for single-contrast and multi-contrast fast magnetic resonance imaging. 107150

Section IV: Classification and interpretation

• 
  Maoneng Hu, Zichen Wang, Xinxin Hu, Yi Wang, Guoliang Wang, Huanhuan Ding, Mingmin Bian:
  High-resolution computed tomography diagnosis of pneumoconiosis complicated with pulmonary tuberculosis based on cascading deep supervision U-Net. 107151

Section III: Modelling & Simulation

• 
  Harnoor Saini, Oliver Röhrle:
  A biophysically guided constitutive law of the musculotendon-complex: modelling and numerical implementation in Abaqus. 107152
• 
  Nicole Hobbs, Sediqeh Samadi, Mudassir M. Rashid, Andrew Shahidehpour, Mohammad-Reza Askari, Min-Sun Park, Laurie Quinn, Ali Cinar:
  A physical activity-intensity driven glycemic model for type 1 diabetes. 107153
• 
  Alp Karakoç, Arttu Miettinen, Emrah Sözümert, Llion Evans, Hüseyin Yigitler, Basak Bostanci, Ertugrul Taciroglu, Riku Jäntti:
  Microstructural evaluation and recommendations for face masks in community use to reduce the transmission of respiratory infectious diseases. 107154

Section II: Biomedical signal and image processing methods

• 
  Gabriele Varisco, Zheng Peng, Deedee Kommers, Zhuozhao Zhan, Ward Cottaar, Peter Andriessen, Xi Long, Carola van Pul:
  Central apnea detection in premature infants using machine learning. 107155

Section III: Modelling & Simulation

• 
  N. Naresh Kumar, D. R. V. S. R. K. Sastry, Sachin Shaw:
  Irreversibility analysis of an unsteady micropolar CNT-blood nanofluid flow through a squeezing channel with activation energy-Application in drug delivery. 107156

Diagnostics and Decision Support

• 
  Amish Kumar, Palash Ghosal, Soumya Snigdha Kundu, Amritendu Mukherjee, Debashis Nandi:
  A lightweight asymmetric U-Net framework for acute ischemic stroke lesion segmentation in CT and CTP images. 107157

Section V: Others

• 
  Dragana Seklic, Tijana Dukic, Dejan A. Milenkovic, Milena Jovanovic, Marko N. Zivanovic, Zoran Markovic, Nenad Filipovic:
  Numerical modelling of WNT/β-catenin signal pathway in characterization of EMT of colorectal carcinoma cell lines after treatment with Pt(IV) complexes. 107158
• 
  Seungho Jeon, Chobyeol Shin, Eunnarae Ko, Jongsub Moon:
  A security scheme for distributing analysis codes supporting CDM-based research in a multi-center environment. 107159

Section II: Biomedical signal and image processing methods

• 
  Lizhu Liu, Yexin Liu, Jian Zhou, Cheng Guo, Huigao Duan:
  A novel MCF-Net: Multi-level context fusion network for 2D medical image segmentation. 107160

Section IV: Classification and interpretation

• 
  Hui Wen Loh, Chui Ping Ooi, Silvia Seoni, Prabal Datta Barua, Filippo Molinari, U. Rajendra Acharya:
  Application of explainable artificial intelligence for healthcare: A systematic review of the last decade (2011-2022). 107161

Section II: Biomedical signal and image processing methods

• 
  Rui Liu, Wei Dai, Tianyi Wu, Min Wang, Song Wan, Jun Liu:
  AIMIC: Deep Learning for Microscopic Image Classification. 107162
• 
  Keisuke Edanami, Masaki Kurosawa, Hoang Thi Yen, Takeru Kanazawa, Yoshifusa Abe, Tetsuo Kirimoto, Yu Yao, Takemi Matsui, Guanghao Sun:
  Remote sensing of vital signs by medical radar time-series signal using cardiac peak extraction and adaptive peak detection algorithm: Performance validation on healthy adults and application to neonatal monitoring at an NICU. 107163

Section III: Modelling & Simulation

• 
  Konstantinos A. Mountris, Esther Pueyo:
  A meshless fragile points method for rule-based definition of myocardial fiber orientation. 107164

Section II: Biomedical signal and image processing methods

• 
  Seung-wan Jeong, Hwan-ho Cho, Seunghak Lee, Hyunjin Park:
  Robust multimodal fusion network using adversarial learning for brain tumor grading. 107165
• 
  Shenyi Qian, Kunpeng Ren, Weiwei Zhang, Haohan Ning:
  Skin lesion classification using CNNs with grouping of multi-scale attention and class-specific loss weighting. 107166
• 
  Ziyu Shu, Alireza Entezari:
  Sparse-view and limited-angle CT reconstruction with untrained networks and deep image prior. 107167
• 
  Pengcheng Zhang, Kunpeng Li:
  A dual-domain neural network based on sinogram synthesis for sparse-view CT reconstruction. 107168

Section III: Modelling & Simulation

• 
  Yuyao Wu, Fei Wang, Yanbin Shi, Guimei Lin, Jinwei Qiao, Li Wang:
  Molecular dynamics simulation of hyaluronic acid hydrogels: Effect of water content on mechanical and tribological properties. 107169

Section II: Biomedical signal and image processing methods

• 
  Qi Lin, Yuli Zhou, Siyuan Shi, Yujuan Zhang, Shaoli Yin, Xuye Liu, Qihui Peng, Shaoting Huang, Yitao Jiang, Chen Cui, Ruilian She, Jinfeng Xu, Fajin Dong:
  How much can AI see in early pregnancy: A multi-center study of fetus head characterization in week 10-14 in ultrasound using deep learning. 107170

Section V: Others

• 
  Kian Esmailian, Babak Mohammadzadeh Asl:
  Correlation-based modified delay-multiply-and-sum beamforming applied to medical ultrasound imaging. 107171
• 
  Halimu N. Haliduola, Frank Bretz, Ulrich Mansmann:
  Missing data imputation using utility-based regression and sampling approaches. 107172

Section II: Biomedical signal and image processing methods

• 
  Marek Wodzinski, Mateusz Daniol, Miroslaw Socha, Daria Hemmerling, Maciej Stanuch, Andrzej Skalski:
  Deep learning-based framework for automatic cranial defect reconstruction and implant modeling. 107173

Section III: Modelling & Simulation

• 
  Valentina Mazzi, Giuseppe De Nisco, Karol Calò, Claudio Chiastra, Joost Daemen, David A. Steinman, Jolanda J. Wentzel, Umberto Morbiducci, Diego Gallo:
  Divergence of the normalized wall shear stress as an effective computational template of low-density lipoprotein polarization at the arterial blood-vessel wall interface. 107174

Diagnostics and Decision Support

• 
  Jiebin Chu, Yaoyun Zhang, Fei Huang, Luo Si, Songfang Huang, Zhengxing Huang:
  Disentangled representation for sequential treatment effect estimation. 107175

Section II: Biomedical signal and image processing methods

• 
  Cong Zhou, J. Geoffrey Chase:
  Low-cost structured light imaging of regional volume changes for use in assessing mechanical ventilation. 107176
• 
  José Negrillo-Cárdenas, Juan-Roberto Jiménez-Pérez, Hermenegildo Cañada-Oya, Francisco R. Feito, Alberto D. Delgado-Martínez:
  Hybrid curvature-geometrical detection of landmarks for the automatic analysis of the reduction of supracondylar fractures of the femur. 107177

Section III: Modelling & Simulation

• 
  Qimei Gong, Luo Huang, Junpan Luo, Yuejiao Zhang, Qingzhen Meng, Jingjing Quan, Zhongchun Tong:
  The practicability of different preparation of mandibular molar restored by modified endocrown with intracanal extension: Computational analysis using finite element models. 107178
• 
  You-Cheng Yu, Tang-Chuan Wang, Tzu-Ching Shih:
  A comprehensive finite-element human ear model to estimate noise-induced hearing loss associated with occupational noise exposure. 107179

Section V: Others

• 
  Savitesh Kushwaha, Rachana Srivastava, Rachita Jain, Vivek Sagar, Arun Kumar Aggarwal, Sanjay Kumar Bhadada, Poonam Khanna:
  Harnessing machine learning models for non-invasive pre-diabetes screening in children and adolescents. 107180

Section II: Biomedical signal and image processing methods

• 
  Yimin Li, Shuo Han, Yuqing Zhao, Fangzhi Li, Dongjiang Ji, Xinyan Zhao, Dayong Liu, Jianbo Jian, Chunhong Hu:
  Synchrotron microtomography image restoration via regularization representation and deep CNN prior. 107181
• 
  Zhou Xu, Fei Yu, Bo Zhang, Qi Zhang:
  Intelligent diagnosis of left ventricular hypertrophy using transthoracic echocardiography videos. 107182

Diagnostics and Decision Support

• 
  Chyh-Ming Lai, Chun-Chih Chiu, Yuh-Chuan Shih, Hsin-Ping Huang:
  A hybrid feature selection algorithm using simplified swarm optimization for body fat prediction. 107183

Section IV: Classification and interpretation

• 
  Hongyuan Huang, Zhijiao You, Huayu Cai, Jianfeng Xu, Dongxu Lin:
  Fast detection method for prostate cancer cells based on an integrated ResNet50 and YoloV5 framework. 107184

Section III: Modelling & Simulation

• 
  Roberto Montes-Robles, Hazael Montanaro, Myles H. Capstick, Javier Ibáñez Civera, Rafael Masot Peris, Eduardo García-Breijo, Nicolás Laguarda-Miró, Ramón Martínez-Máñez:
  Tailored cancer therapy by magnetic nanoparticle hyperthermia: A virtual scenario simulation method. 107185
• 
  Zhongzhi Jia, Junhao Mei, Wei Ding, Xi Zhao, Wen Gong, Haiyang Yu, Lihao Qin, Zeyu Piao, Wenhua Chen, Liming Tang:
  The pathogenesis of superior mesenteric artery dissection: An in-depth study based on fluid-structure interaction and histology analysis. 107187

Section V: Others

• 
  Ruiqi Feng, Li Zhuo, Xiaoguang Li, Hongxia Yin, Zhenchang Wang:
  BLA-Net: Boundary learning assisted network for skin lesion segmentation. 107190

Section III: Modelling & Simulation

• 
  Beichuan Tang, Jiemeng Yang, Yingying Zhang, Xianjun Ren, Tao Jiang, Zhongjun Mo, Yubo Fan:
  Incorporating strategy in hybrid surgery for continuous two-level cervical spondylosis from a biomechanical perspective. 107193
• 
  Wei Qu, Xiaofan Li, Hao Huang, Chiyu Xie, Hongqing Song:
  Mechanisms of the ascites volume differences between patients receiving a left or right hemi-liver graft liver transplantation: From biofluidic analysis. 107196