CeGaT GmbH

𝗥𝗲𝘀𝗲𝗮𝗿𝗰𝗵𝗶𝗻𝗴 𝘁𝗵𝗲 𝗹𝗶𝗻𝗸 𝗯𝗲𝘁𝘄𝗲𝗲𝗻 𝗺𝗶𝗰𝗿𝗼𝗯𝗶𝗼𝗺𝗲𝘀 𝗮𝗻𝗱 𝗱𝗶𝘀𝗲𝗮𝘀𝗲𝘀 The composition of the human microbiome is increasingly recognized as a significant determinant of health and disease. The complex relationship between the gut microbiome and various diseases and the microbiome's impact on drug responses are attracting scientific attention. However, microbiomes and their complex relationships can also be found on other body sites, such as the skin, mouth, or nose.  Understanding these microbial functions and relationships is crucial for researchers studying disease mechanisms, therapeutic responses, or environmental biochemistry. Shotgun metagenome sequencing analyzes the entire DNA content of a sample and enables the accurate detection of microbes, such as bacteria, archaea, fungi, protozoa, and viruses, down to the species level. Please have a look at our portfolio: https://lnkd.in/eXvyez2g #metagenomics #microbiome #sequencing #research #science #NGS

𝗦𝗽𝗶𝗻𝗮𝗹 𝗺𝘂𝘀𝗰𝘂𝗹𝗮𝗿 𝗮𝘁𝗿𝗼𝗽𝗵𝘆: 𝗻𝗲𝘄 𝗺𝗲𝘁𝗵𝗼𝗱 𝘂𝗻𝗰𝗼𝘃𝗲𝗿𝘀 𝗵𝗶𝗱𝗱𝗲𝗻 𝗽𝗿𝗲𝗱𝗶𝘀𝗽𝗼𝘀𝗶𝘁𝗶𝗼𝗻. CeGaT has developed a particular MLPA method to test on so-called "silent carriers" for spinal muscular atrophy. This is performed as standard testing within the Family Planning Panel. In couples who wish to have children, an increased risk of a hidden carrier can be detected. For more information, please take a look at our news text: https://lnkd.in/eGNY4bq7 #genetics #diagnostics #prenataldiagnostics #geneticdiseases #health #familyplanning

We are most happy to share data on our real-world observation of 173 glioblastoma patients who received a fully personalized neoantigen-based peptide vaccine alongside their treatment regimen. The results are very promising: this immune-based personalized approach is not only feasible in a clinical setting but also well-tolerated. Importantly, patients who developed immune responses against multiple neoantigens have a significant survival benefit. Our hope is that one day patients will have access to individualized immunotherapies - this data is certainly an important step in this direction. Have a look at the publication here: https://lnkd.in/ggN4gmBP #publication #immunotherapy #glioblastoma #genetictesting #tumordiagnostics #science #research

Single-cell RNA sequencing effectively identifies rare cell groups in complex samples. It's ideal for tracking cell type proportion changes over time in experiments with multiple collection points. We offer high-throughput 3' Single-Cell RNA Sequencing to help you investigate your samples' cellular diversity. For more information, please take a look at our website: https://lnkd.in/ebHJcqm5 #singlecell #RNA #sequencing #genetics

Every tumor disease is unique. This is why genetic profiling is necessary to uncover the full spectrum of treatment options. Our managing director and co-founder, Dr. Dr. Saskia Biskup, presents real-life cases that illustrate the transformative impact of genetic testing on patient care. In this video clip, she talks about a patient who was initially diagnosed with glioblastoma and treated accordingly. The turning point came with comprehensive genetic testing, which led to a decisive change in the treatment. Discover the profound difference that genetic insights into a tumor disease can make. Learn more: https://lnkd.in/eNHeb_2P #genetics #diagnostics #tumor #tumordiagnostics

As one of the first laboratories, CeGaT has included 𝘙𝘕𝘜4-2 into the exome enrichment (CeGaT ExomeXtra®). Pathogenic 𝘙𝘕𝘜4-2 changes in the indication "neuronal developmental disorders" and the associated symptoms are thus recognized and reported. Learn more in our news text: https://lnkd.in/ge2cgGAP #genetics #diagnostics #laboratory #exome #neuronal

𝗠𝗮𝗷𝗼𝗿 𝘂𝗽𝗱𝗮𝘁𝗲 𝗼𝗳 𝗼𝘂𝗿 𝘁𝘂𝗺𝗼𝗿 𝗱𝗶𝗮𝗴𝗻𝗼𝘀𝘁𝗶𝗰𝘀 We are excited to announce the latest updates to our CancerPrecision® panel, reflecting the newest scientific and medical findings: • expanded gene list and breakpoint enrichment for DNA-based gene fusion diagnostics • inclusion of more pharmacogenetically relevant genes: 𝘊𝘈𝘊𝘕𝘈1𝘚 and 𝘕𝘜𝘋𝘛15 • enhanced ability to detect oncogenic viruses Our RNA-level gene fusion panel, CancerFusionRx®, also received significant updates: • expanded scope of analyzed breakpoint regions for targeted detection of recurrent gene fusions • now capable of detecting expressed viral genes at the RNA level, including HPV, EBV, MCV, and CMV For more information, take a look at our news text: https://lnkd.in/gQFSRxFq #diagnostics #genetics #tumor #update #cancer #oncology

The next panel has been revised as part of our regular updates. The Diagnostic Panel for Neuromuscular Diseases is the ideal tool for diagnosing genetic diseases of the muscle as well as diseases of the nerve fibers that activate the muscle. Like all our panels, it is based on our proprietary, high-quality ExomeXtra® enrichment. It covers all protein-coding regions as well as disease-relevant intronic and intergenic variants. In addition, the ExomeXtra® enrichment enables a genome-wide CNV calling with similar performance to array CGH. Our panel thus provides the ideal basis for genetic diagnostics of neuromuscular conditions. Have a look at our website to learn more about this panel: https://lnkd.in/eCYDqFQ6 #genetics #diagnostics #update #neuromuscular

Did you know small RNA sequencing can identify biomarkers for disease diagnostics or classification, like for cancer? Small RNAs are involved in various functions, including RNA interference, gene silencing, and epigenetic modifications. By sequencing, we can determine the diverse expression of all small RNAs in a sample. Analyzing these expression profiles helps us to better understand dysregulation under pathological conditions and to identify key biomarkers in disease pathogenesis. Learn more here: https://lnkd.in/ecuYBZAe #smallRNA #sequencing #NGS

Work with us in one of the most exciting fields of life sciences: CeGaT is looking for a Content Marketing Manager (m/f/d) to join our dynamic team in Tübingen, Germany! If you would like to contribute to the advancement of genetic diagnostics and sequencing services, take a look at our open positions and apply today: https://lnkd.in/e9wytZuN #joinourteam #contentmarketing #openposition