Enzymicals AG

Enzymicals has announced the appointment of Dr David Liese as its new Chief Executive Officer, following a long-planned succession programme. Dr Liese will replace Dr Erik de Vries, who announced his intention to retire from Enzymicals earlier this year. More information: https://lnkd.in/dVaAg-vG

We're excited to share our latest publication in Food Chemistry, developed with the MACBETH project consortium! The study, Modeling of enzymatic transesterification for omega-3 fatty acids enrichment in fish oil by M. Ongis et al., details how enzyme-based transesterification enrich omega-3 fatty acids, specifically EPA and DHA. The study assesses a kinetic model for transesterification with varying enzyme load and ethanol concentration, which improves ω3 mass fraction in acylglycerols from 35% to 52%. The process was carried out in our flow reactor at a throughput of 1.5 L per hour, catalysed by an enzyme immobilised by ChiralVision BV, easily producing over 100 kg of product! This paves the way for sustainable and efficient omega-3 enrichment processes. Read the paper: https://lnkd.in/dKHBGGeB Curious to learn more? Contact us today and discover how Enzymicals can support your next innovation! #biocatalysis #greenchemistry #foodchemistry #enzymes #BiotechInnovation #EnzymeTechnology #Sustainability Enzyme Technology Alliance

Day two of CPhI. We’ve had many meetings already, but also walked many miles. From Hall 2 to Hall 24 is more than a km! Make the trip out here - 24D72.

Enzymicals invites you to meet our experts, represented by Rainer Wardenga and Christin Peters at booth 24D72 at CPHI from 8th to 10th October 2024. Let us inspire you on how we can support your concepts in the field of industrial biocatalysis.

🔬 IP Licensing opportunity from Enzymicals! 🔬 Enzymicals has a recently granted US and EU patent for the production of chiral amines via transaminase reactions with salt precipitation. This in-situ product crystallization technology marks a breakthrough in the enzymatic synthesis of chiral amines, requiring only equimolar quantities of the amine donor, with the added benefit of product isolation through simple filtration. Independently and successfully demonstrated by various companies and universities at scales of up to 100 kg, this proprietary technology is now available for licensing or outright acquisition. Let’s explore this exciting opportunity at CPHI Milan! Visit us at Booth 24D72 in the Fine Chemicals Zone, and learn how this process can benefit your operations. #Patent #ChiralAmines #Transaminase #CPHI2024 #FineChemicals #SustainableChemistry #Innovation #GreenChemistry #CPHI

🔄 Enzyme-Catalyzed Ester/Amide Transformation: Precision Green Chemistry🧪 The third article in our series on enzyme-catalysed chemical transformations provides some insights into selective enzyme-catalysed ester and amide transformations of small molecules. Enzymes such as lipases, amidases, proteases and esterases are well known and widely used in industry due to their exceptional enantioselectivity, regio- and chemoselectivity. They can be used in synthesis, resolution, hydrolysis, alcoholysis and transesterification/amidation modes - all under mild, environmentally friendly conditions. The ability to avoid environmentally harmful coupling reagents makes the biocatalytic approach both sustainable and scalable. A speciality of enzymes is the ability to synthesise esters and amides in water, which provides an additional advantage for sustainable green chemistry processes. At Enzymicals, we have access to hundreds of these enzymes ready for screening to identify the optimal biocatalyst for your target conversion. Once we've identified the right enzyme, we'll move forward with a seamless transition from screening to synthesis. Want to explore the possibilities of selective ester or amide conversion for your project? Contact us today and let's get started! #EnzymeScreening #Biocatalysis #GreenChemistry #Enzymes #SustainableSynthesis #APIs #CRO #ProcessDevelopment

🌍 Join Enzymicals at CPHI in Milan! 🌍 As we have been since 2015, we will again be an exhibitor at CPHI this year. Visit us in Milan at Booth 24D72 in the Fine Chemicals Zone to discover how we can be your trusted partner for industrial biocatalysis, with 15 years of expertise delivering end-to-end solutions – from catalyst lead-finding to process optimization and scale-up, spanning from gram- to ton-scale. 🔬 Seamless Transition from Screening to Synthesis 🔬 Our chemical expertise ensures that screening hits are quickly translated into optimized processes and kilogram-scale syntheses through tailored development programs. We offer scalable solutions, including feasibility studies, DOE-based process intensification, and seamless scale-up of both enzyme production and chemo-enzymatic processes, including downstream processing – ready for tech-transfer. Our industry-exclusive approach covers everything from traditional batch reactions to advanced enzymatic flow and rotating bed reactors, ensuring efficient and sustainable processes. 📅 Let’s discuss how we can support your next project! #CPHI2024 #Enzymes #GreenChemistry #IndustrialBiocatalysis #FineChemicals #ProcessOptimization #SustainableChemistry

Celebrating 15 Years of Enzymicals! We’re excited to mark this milestone with the entire Enzymicals team! To celebrate, all our employees enjoyed a fantastic boat trip, followed by a delicious meal and a visit to a local brewery. 🍻 Over the past 15 years, Enzymicals has proudly supported numerous projects in the field of industrial biocatalysis, contributing to greener, more sustainable chemistry. This success wouldn’t have been possible without the dedication and passion of our incredible team. 💚 Here’s to many more years of innovation and positive impact! Thank you to everyone who has been part of this journey with us. #Enzymicals #Biocatalysis #SustainableChemistry #GreenInnovation

🔄 Enzyme-Catalyzed Alcohol-Carbonyl Interconversions: Precision Redox Chemistry 🧪 In our latest post on enzyme-catalyzed chemical conversions, we’re diving into selective redox reactions. These reactions are catalyzed by enzymes like ketoreductases (KREDs), which offer exceptional enantioselectivity, along with high regio- and chemoselectivity. These enzymes enable efficient and highly specific transformations between alcohols and carbonyl compounds, all under mild reaction conditions. This not only ensures environmentally friendly processes but also reduces the need for harsh chemicals, making the approach both sustainable and scalable. At Enzymicals, we have access to nearly 1,000 KREDs, ready for screening to identify the optimal biocatalyst for your target conversion. Once we’ve identified the right enzyme, we’ll move forward with biocatalytic process development as well as fermentation optimization, ensuring that the biocatalyst can be produced economically at scale. Want to explore the possibilities of selective redox reactions for your project? Reach out today, and let’s get started! #EnzymeScreening #Biocatalysis #KREDs #AlcoholCarbonylInterconversion #Sustainability #GreenChemistry

We were excited to participate in the International Congress on Biocatalysis in Hamburg! It was a pleasure to connect with leading experts in the field and to be inspired by the cutting-edge advancements in biocatalysis. The state-of-the-art science presented at the conference has given us fresh ideas and renewed motivation as we continue to innovate and push the boundaries in enzyme technology. A big thank you to the organizers and all the brilliant minds we had the opportunity to meet! #SustainableChemistry #Biocatalysis #Enzymes #Biotechnology #Research