HARMLESS

The latest HARMLESS activities have been highlighted in the October #NSCupdate: 👉 Factsheet on perovskites 👉 Recap of the NanoTox conference 👉 Recap of the final dissemination event of the NMBP-16 sister projects (DIAGONAL, HARMLESS and h2020 SUNSHINE) Have a look to don't miss any of the latest news of the EU NanoSafety Cluster projects!

Countdown for #SETACVienna! I have the pleasure to co-chair two sessions on different topics each with a knowledgeable & diverse team of chairs. Submissions are most welcome.

Just a month ago, the whole @HARMLESS consortium had the pleasure to attend the 11th International Conference on NanoToxicology – #NANOTOX2024, held in the stunning city of Venice! 🏛️✨ It was a great success, organised jointly by the three NMBP-16 projects DIAGONAL, HARMLESS and h2020 SUNSHINE, as their final dissemination activity! Catch the vibe of the event in the video below and dive into the details of HARMLESS contribution by reading the full article here: https://lnkd.in/gSKxwwmc #Nanotechnology #NanoToxicology #SSbD #Research #Sustainability #Innovation

Last but not least, Day 3 of #NANOTOX2024 on September 25th wrapped up with more insightful presentations from HARMLESS partners! It’s been an incredible conference sharing cutting-edge research and fostering collaboration. Grateful for the inspiring discussions and networking opportunities! 👉 Oral presentations: * Andrea Haase (Bundesinstitut für Risikobewertung) - Title “The HARMLESS Early Warning System” * Blanca Suarez-Merino (TEMAS Solutions) - Title “Safe and Sustainable by Design framework for advanced materials: the HARMLESS approach” * Veronique Adam (TEMASOL) - Title “Safe-and-Sustainable-by-Design for Advanced Materials - A case study on the agricultural use of imogolites”  * Andrea Haase (BfR) - Title “Developing a NAMs qualification system to support regulatory acceptance”  * Penny Nymark (Karolinska Institutet) - Title “Validation of NAMs for nanomaterials: the importance of big data and its FAIRification for accelerating risk assessment” 👉 Poster presentations: * Veronique Adam (TEMASOL) - Title “Life Cycle Assessment of Advanced Materials – A case study of graphene oxide in drinking water filters”  * Aleksandra Nowak (University of Gdansk) - Title “Calculations for band gap of Ni-doped LaCoO3 (LaCoxNi1-xO3). A DFT+U approach”

Very nice opportunity to present your research at #SETACVienna. Submitt your abstract until 20th November!

Wrapping up #NANOTOX2024 Day 2 - September 24th was packed with HARMLESS partners, showcasing their research through insightful oral & poster presentations. Additionally, we enjoyed the 24/7 #PitchPosterSession with Susanne Resch & Judith Friesl as moderators, were scientist presented their research in 24 sec & 7 keywords! 👉 Oral presentations: * Mario P. (Bundesinstitut für Risikobewertung) - “Challenges and insights in evaluating nanofiber toxicity using differentiated THP-1 cells: The importance of methodological standardization and material characterization” * Susan Dekkers (TNO) - “Making a simple and sensitive DSS for SSbD in the early innovation stages” * Wendel Wohlleben (BASF) - “Inhalation hazard of multicomponent perovskites by New Approach Methodologies (NAMs) for SSbD comparative screening” * Alicja Mikolajczyk (University of Gdansk) - “New Nanoinfomatics Approach for Joint Effect Prediction of Advanced Multicomponent Nanomaterials: Computational Tool to Support SSbD Strategy” * Otmar Schmid (Helmholtz Munich) - “Monitoring deposition, spatially resolved dosimetry and biokinetics of inhaled nanoparticles with cellular resolution throughout the entire murine lung” * Lin Yang (HMGU) - “AI-powered 3D imaging unveils fresh perspectives on pulmonary nanoparticle delivery in healthy and fibrotic murine lungs” * Mona Connolly (INIA) - “Use of a fish model and the oxidative stress paradigm in an integrated testing strategy for NM hazard assessment; a proof of principle study”  * Agnieszka Gajewicz-Skrętna (UG) - “A data-driven machine learning approach for predicting the hazard of advanced materials based on the integration of in silico, in chemico, and in vitro data”  * Wendel Wohlleben (BASF) - “Concepts of similarity in a SSbD context: finding a balance of safety and functionality for five multicomponent Quantum Dots”  * Wouter Fransman (TNO) - “Enabling Safe and Sustainable Innovation: transparent decision support” 👉 Poster presentations:  * Siân Brooks (Swansea University) - “Investigating the mechanisms responsible for multi-component nanomaterial toxicity using advanced lung models at the air-liquid interface: a tiered testing approach” * Marion Blayac (HMGU) - “Surface area-based hazard ranking of aerosolized nanomaterials from epithelial lung cells cultured under air-liquid interface conditions: A metaanalysis” * Hongisto Vesa (Misvik Biology) on behalf of Gergana Tancheva (IDEAconsult) - “Automatic workflow for in vitro high-throughput screening data fairification, preprocessing and scoring: A case study on nanomaterials” * Fabienne Testard (Commissariat a l'Energie Atomique et aux Energies Alternatives) - “Modified imogolite nanotubes: How inner functional group modification in multicomponent HARN impact the toxicity” * Wendel Wohlleben (BASF) - “Assessing the dust released from inorganic aerogel mats: occupational release scenarios simulation and hazard implications in a SSbD context”

We congratulate Lianyong Han, from Helmholtz Munich, for winning the #award to one of the BEST ORAL PRESENTATIONs at #NANOTOX2024 in Venice, with his talk "Pathogenic dynamics of lung macrophages during injury and regeneration caused by fiber-shaped nanomaterials”! Your dedication and impactful research continue to stand out—an achievement well-earned! #lungresearch #fibershapednanomaterials

During #NANOTOX2024 Day 1 on 23 Sept, several partners from the HARMLESS project showcased their groundbreaking research through both oral and poster presentations. It’s inspiring to see the innovative outcomes from our collaborative efforts come to life! 👉 Oral presentations:  * Lianyong Han (Helmholtz Munich) - Title “Pathogenic dynamics of lung macrophages during injury and regeneration caused by fiber-shaped nanomaterials” * Hongyu Ren (HMGU) - Title “Linking the molecular mechanisms of alveolar macrophage cell death induced by inhaled nanoparticles with the subsequent pathological outcome” * Roland Grafström (Karolinska Institutet ) - Title “The HARMLESS Artificial Intelligence High-Throughput Screening Approach (AI-HTS) to Materials Safety Evaluation” * Verónica Dumit (Bundesinstitut für Risikobewertung) - Title “Assessing nanofiber pathogenicity through an omics-based meta-analysis” * Pekka Kohonen (KI) - NAM-focused materials safety assessment utilizing predictive toxicogenomics space (PTGS)-driven retrieval of adverse outcome pathways in transcriptomics data” * Wouter Fransman (TNO) - Title “Nano Exposure Quantifier for Safe-by-Design of Advanced Materials” 👉 Poster presentations:  * Wendel Wohlleben (BASF) - Title “ROS Activity in Carbonaceous Nanoparticles: The Influence of Surface Area and Chemistry” * Michalina Miszczak (University of Gdansk) - Title “Dynamic QSAR modeling – time-dependent models of genotoxicity for advanced materials”

🌍✨ On September 27th, our amazing team from BNN - BioNanoNet joined the European Researchers' Night #ERN2024 in Graz, Austria! 🎉 At the Life is Science event, we hosted an interactive booth to bring nanotechnology closer to the public. From hands-on activities to fun games, we showcased how HARMLESS is shaping a better, more sustainable future! 🌱🔬 It’s always a pleasure to make science accessible and exciting for everyone, whether you're a scientist or just curious about the world around you! Read more about it here: https://lnkd.in/d4gDgJS6 #science4all #nanomaterials #advancedmaterials #nanotechnology #safety #sustainability #innovation

Another success story of the collaboration work between the EU NanoSafety Cluster projects NMBP-16 (DIAGONAL, HARMLESS, and h2020 SUNSHINE) as well as SUNRISE Project and #POTENTIAL! #riskassessment #AdMA #NAMs #SbD #SSbD