PROTEROS biostructures GmbH

Our Discovery Solutions are the integrated early drug discovery engine of choice for even the most challenging targets! We have customized solutions available to cater for all projects: “Qualified Hits” program identify and fully characterize hit compounds to deliver Qualified Hits using the full power of our Discovery Engine. From target nomination to milestone completion: ✅ Protein Sciences ✅ Biochemical and Biophysical Assays ✅ Fragment and small molecule library screening ✅ Hit ID ✅ Orthogonal hit verification ✅ Hits structurally validated by X-ray crystallography and Cryo-EM ✅ Extended hit profiling 🔍 Discovery Your Way Flexible, open access to our protein sciences, structural biology, assays, biophysics, screening capabilities - your choice according to your project demands! 🔍 High-quality in house library collections offered by Proteros for immediate screening and seamless post-screening processes ✅ Proteros owns 4 libraries: 3k Fragment, 41 k Range Finder (high sp3, fragment to small molecule), 150k Cluster-based small-molecule library, 186k Centroid-based small-molecule library ✅ Hand-selected compounds/fragments from Enamine and other high quality vendors ✅ Compounds and fragments were selected to enable rapid hit expansion by analoguing ✅ Libraries are target agnostic and can be used for all target classes ✅ Screening technologies include: ✅ Surface Plasmon Resonance, SPR (Biacore 8K+) ✅ Reporter Displacement Assay (RDA) ✅ Complex Formation Assay (CFA) ✅ Functional Enzymatic Assays ✅ TSA ✅ MST (NanoTemper) ✅ nanoDSF (NanoTemper) ✅ nanoBRET (Promega) Get on your way to reaching right faster, today https://lnkd.in/ev33Ufs6 #DrugDiscovery #ProteinSciences #Biophysics #Biochemistry #FragmentLibrary #Assays #Biologics #StructuralBiology

For a protein to be "fit-for-function" and work in your experiment it needs more than just a Purity %. It needs to have the right functionality, right construct, right homogeneity, right post-translational modifications, right complex composition, right stability, right species, right activity and right purity as well. We don't just make protein, we understand the downstream applications and deliver the RIGHT protein for your application https://lnkd.in/enAq4zkE #GeneToProtein #ProteinScience #GeneSynthesis #GeneConstructDesign #DrugDiscovery

🧠 Discovery on Target 📆 September 30 - October 3, 2024 📍 Sheraton Boston, Boston, USA & Online We are pleased to announce that we will be attending Discovery on Target as a corporate sponsor! Dr. Lars Neumann, Head of Integrated Discovery Solutions Services, will be giving a talk titled ‘Pocket-Specific Fragment Hits for RIPK1 and their Evolution into Long Residence Time Inhibitors’. This will be Symposium 1- Strategies for Targeting Kinases; Sept. 30th 10:30am-11:00am. There will be a Proteros booth where you can meet Steven L. Holshouser, Ph.D., VP of Business Development, and Dina Dunn, SVP of Global Strategic Business Development to discuss your drug development projects and how we can help you reach right faster! In addition, we are excited to announce the launch of our new offerings for screening capabilities and structural biology during the conference. If you’d like to book a meeting slot ahead of time, please message Steven L. Holshouser, Ph.D. to arrange. #DiscoveryOnTarget #DOT2024 #DrugDiscovery #PocketSpecificFragment #RIPK1 #DrugDevelopment #StructuralBiology #TargetingKinases

Search our gallery structures database! 🔎🔎 Benefit from our fast and reliable turnaround times. We’ve accrued many years of experience across a plethora of projects. Having extensively studied these crystal systems extensively, we've established tried-and-tested methodologies, protocols, and SOPs to maximize success. This allows an ideal basis for the determination of high-resolution Protein-Ligand-Structures (PLS) with customer ligands of interest, as PLS can typically be generated in a time scale of a few weeks with attractive pricing. Find out more and accelerate your drug discovery projects from here 🚀 https://lnkd.in/ewEMwMER #StructuralBiology #DrugDevelopment #ProteinLigandStructures

📝 Call for Abstracts 📅 Submission deadline: September 1, 2024 We invite you to submit your research abstracts for the upcoming IBA Conference. ICYMI: We're partners for the Industrial Biostructures America conference, at the MassBio Hub Conference Center in Boston, on October 21 & 22, 2024. Hosting structural biology enthusiasts from around the globe, this unique event is set to feature some inspirational and innovative scientific sessions, poster presentations, and the chance to network with industry peers. This is a prime opportunity to showcase your work and contribute to the collective advancement of structural biology and drug discovery. To submit your abstracts, visit: https://lnkd.in/eCNbkKXc #IBAConference #StructuralBiology #DrugDiscovery #ResearchInnovation #ResearchAbstract #Biostructures #IndustrialBiostructures

📌 Welcoming Dr. Ashiq H. Khan as our new Chief Commercial Officer 📌 We are excited to announce the appointment of Dr. Khan, a distinguished veteran of the biotech, pharmaceutical, and technology sectors. He brings a wealth of experience and brilliant, proven track record in driving commercial success and strategic growth. Leading our global commercial strategy and business development, Dr. Khan will focus on expanding our market presence, fostering key partnerships, and shaping new business ventures. We’re very much looking forward to how he will help us achieve our goals. "I am honored to join Proteros at such an exciting time," said Khan. "The company’s dedication to advancing structural biology, backed by over 20 years of trust from the pharma and biotech industries, and its impressive portfolio of industry-validated solutions for both small molecules and biologics are truly inspiring. I look forward to working with the talented team at Proteros to drive our commercial success and contribute to the company’s continued growth and innovation." Dr. Khan holds a Ph.D in Molecular Neurobiology from University of Cologne, Germany, with a major part of his research conducted at Harvard University, USA. He also holds a Postdoc from Yale University, USA, with business strategy studies from INSEAD. He is also a proud father of two. This exciting appointment reflects our commitment to bringing on board top-tier talent to lead our company into its next phase of expansion and continued success! #MeetTheTeam #NewStarters #Proteros

🇮🇹Client roadshow 🇨🇭 🧠 Visiting clients and potential new clients to discuss their protein science and drug discovery projects: 📆 July 30 2024 📍 Milan, Italy 📆 July 31 2024 📍 Lausanne, Switzerland Are you based in Milan, Italy or Lausanne, Switzerland? Would you like to meet up to discuss your protein science/drug discovery projects? Joanna Deek, Ph.D, Director of Proteins and Biophysics, and Dr. Tanja Vukicevic, VP of Business Development, will be visiting your beautiful cities to meet with clients, and those considering partnering with Proteros on their projects. If you’d like to meet and discuss how we can help, send Dr. Tanja Vukicevic a message to book your slot 📥 #ProteinSciences #Biophysics #CryoEM #DrugDiscovery

🇳🇱 Client roadshow 🧠 Visiting clients and potential new clients to discuss their protein science and drug discovery projects 📆 July 26 2024 📍 Holland, The Netherlands Are you based in the Netherlands, or more specifically, Holland? Would you like to meet up to discuss your protein science/drug discovery projects? Dr. Stephan Krapp, Director of Protein Crystallography, and Dr George Buckley, VP of Business Development, will be in the vicinity to meet with clients, and those considering partnering with Proteros on their projects. If you’d like to meet and discuss how we can help, send George Buckley or Dr. Stephan Krapp a message to book your slot 📥 #ProteinCrystallography #ProteinScience #DrugDiscovery #Crystallography

There isn’t necessarily a one-size-fits-all approach to projects that require our assays, biophysics, and screening services. Whether you’re probing binding sites and modes of action, analyzing biochemical activity, or looking to determine and optimize kinetic profiles, we can help! Get in touch and we can help develop the right assay, with the right technologies, and reach right faster! https://lnkd.in/edAj-hee #biophysics #assays #biochemistry #proteinscience #structuralbiology

You’ve run your biologics discovery program. It’s passed the engineering phase and now you’re considering how to further characterize it. Our “one-stop-shop” for expression, analytics-driven purification, characterization, and developability assessment is what you need. Our biologics team are experts in a plethora of formats, including bs-Ab, ms-Abs, cytokines, non-human antibody formats and antigens. We deliver the right biologics with acute assembly, purity, structural and biophysical characterization, and early developability assessment (non GxP). This approach helps you reach right faster on your downstream applications. Still considering your biologics discovery next steps? Look no further https://lnkd.in/e2V2UJRM #Biologics #ProteinScience #BiologicsDiscovery #DrugDiscovery #DownstreamApplications