Quantifoil

We had the pleasure of sitting down for a conversation with Bharat Reddy, a Senior Scientist at Rectify Pharma, to hear more about the exciting first published commercial use of our HexAuFoil® ultra-small hole gold-on-gold grids. Bharat and his team have used HexAuFoil grids to uncover new structural insights into the bile salt export pump (BSEP), a liver-based protein that plays a crucial role in bile regulation. Switching to HexAuFoil has delivered almost a half-angstrom improvement in resolution, enabling the team to eliminate new therapeutic candidates that might pose toxicity risks due to BSEP’s known ability to bind to multiple compounds. You can watch the full interviewhere: https://lnkd.in/gENCndYr #cryoEM #structuralbiology #drugdiscovery

Catch them while you can! Available to ship now: HexAuFoil ultrasmall holey gold #cryoem specimen supports for better images every time. “If I need small molecule bound structures […] the HexAuFoils will be my go-to grids.” Imre Gonda University of Zurich Order today - https://lnkd.in/gyaBGHw3

HexAuFoil® grids deliver virtually movement-free imaging thanks to their revolutionary small-hole, all-gold design. But the best part? Preparing your #cryoEM samples is as simple as ever! Watch this short demo with Dr. Peter Harrison @DiamondLightSou: https://lnkd.in/gKgci3PK

We had the pleasure of sitting down for a conversation with Bharat Reddy, a Senior Scientist at Rectify Pharma, to hear more about the exciting first published commercial use of our HexAuFoil® ultra-small hole gold-on-gold grids. Bharat and his team have used HexAuFoil grids to uncover new structural insights into the bile salt export pump (BSEP), a liver-based protein that plays a crucial role in bile regulation. Switching to HexAuFoil has delivered almost a half-angstrom improvement in resolution, enabling the team to eliminate new therapeutic candidates that might pose toxicity risks due to BSEP’s known ability to bind to multiple compounds. You can watch the full interviewhere: https://lnkd.in/g-N_inVE #cryoEM #structuralbiology #drugdiscovery

With a revolutionary small-hole, all-gold design, HexAuFoil® grids deliver virtually movement-free imaging and exceptional uniformity in ice thickness. Best of all, preparing your samples for #cryoEM is as straightforward as with any other support grid! Watch our quick video demo led by Peter Harrison (Electron Microscopy Scientist, eBIC at Diamond Light Source), as he walks through the step-by-step process of HexAuFoil grid preparation: https://lnkd.in/gaawh82Z #cryoEM #structuralbiology #microscopy

A very merry Christmas and a happy new year from all at Quantifoil!

Calling all #cryoem peeps this Christmas - we've got a challenge for you! Ever spot a #gridinthewild? They're everywhere once you look - as you can see from our collection here! Share the ones you find and tag us in - there'll be goodies in the post for the best images!

Final conference of the year and what a pleasure to spend it MRC Laboratory of Molecular Biology (LMB) with British Crystallographic Association BSG Winter Meeting. Lovely day discussing #cryoem and #crystallography, and congratulations to Peter Harrison eBIC Diamond Light Source for taking away the final grid race prize, with a fab 16 sec time!

With a revolutionary small-hole, all-gold design, HexAuFoil® grids deliver virtually movement-free imaging and exceptional uniformity in ice thickness. Best of all, preparing your samples for #cryoEM is as straightforward as with any other support grid! Watch our quick video demo led by Peter Harrison (Electron Microscopy Scientist, eBIC at Diamond Light Source), as he walks through the step-by-step process of HexAuFoil grid preparation: https://lnkd.in/gYNxRyjS #cryoEM #structuralbiology #microscopy

And as the sun set on the final day of the 5th GDR Appicom meeting in BEAUTIFUL Carry-le-Rouet, we had FOUR possible #cryoEM grid race winners, all tied on 19 secs each: Guillaume Bossan Institute of Physico-Chemical Biology (IBPC) Paris, France, Julie Couston IRIM Institut de Recherche en Infectiologie de Montpellier, and Nejma Rabhi and Pierre Maisonneuve Institut Européen de Chimie et Biologie (IECB)! Astonishing scenes - less than 0.5 secs between them and so... We had a run off competition - from which Nejma Rabhi emerged triumphant, beating her own time with an amazing 18 sec run, and taking away the prize. But wait for the twist... Because after the close of the competition, along came Christelle AlJamous Institut de Génomique Fonctionnelle - IGF with a stunning 15 sec entry, missing the prize but gaining the bragging rights! Incredible #cryoEM tweezer skills all round! (and one last pic of the beauty of Carry-le-Rouet).