Alternatives to draining the blood of horseshoe crabs for detecting bacterial endotoxins? 🩸🔹 LabReNew's comment is absolutely right - in fact, synthetical/recombinant alternatives are apparently as good in performance! Here is a nice review for all who want to know more: https://lnkd.in/dnbvdU28
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How do we treat animals in science? How blue blood worth $60 000 raises questions: Horseshoe crabs have blue blood. Instead of using hemoglobin like we humans do, their blood contains hemocyanin. There, copper binds oxygen, leading to a blue color. Why is it so expensive? The reason is that certain components allow the blood to coagulase quickly when in contact with small amounts of bacterial endotoxin – making it a valuable test for medical applications. The big demand from pharma and research has led to a decline in the number of naturally occurring horseshoe crabs. The worst, synthetical alternatives for these medical tests are available! #Science #Fasctination #FunFact #Curiosity #Biochemistry #Viral #Animalabuse #3R