DNA Script was created to revolutionize DNA synthesis with enzymes. Our core R&D efforts have produced innovations in enzyme engineering, surface and nucleotide chemistries, and instrumentation. The integration of these innovations has resulted in SYNTAX™️, the world’s first benchtop DNA printer powered by enzymatic technology. With continued advancement and innovation, we believe DNA Script’s enzymatic DNA synthesis technology is poised to become the engine of genomics research and personalized medicine.
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67, Avenue de Fontainebleau
94270 Le Kremlin-Bicêtre, Île-de-France, FR
279 E Grand Ave
Suite 440
94080 South San Francisco, California, US
Welcome Alice, we're super excited to have you on board.
I am excited to share that I have embarked in a new professional challenge by joining DNA Script as a Product Manager. If you’re curious about Enzymatic DNA Synthesis and how it can help you overcome some of your challenges in gene editing and synthetic biology, please reach out!
DNA Script a republié ceci
From 3 Nucleotides to Precision Medicine: My Journey with Enzymatic DNA Synthesis Over more than a decade, I’ve led DNA Script from a bold idea to a revolutionary technology that’s transforming life sciences. As we enter a new growth phase, I’m excited to step into the role of Chief Scientific Officer and focus on advancing our scientific impact. In this article, I reflect on our journey, from early challenges to becoming a cornerstone technology in precision medicine and make our customers and partners successful in their projects. Read more about how we’re pushing the boundaries of science and shaping the future of life sciences !
DNA Script a republié ceci
From 3 Nucleotides to Precision Medicine: My Journey with Enzymatic DNA Synthesis Over more than a decade, I’ve led DNA Script from a bold idea to a revolutionary technology that’s transforming life sciences. As we enter a new growth phase, I’m excited to step into the role of Chief Scientific Officer and focus on advancing our scientific impact. In this article, I reflect on our journey, from early challenges to becoming a cornerstone technology in precision medicine and make our customers and partners successful in their projects. Read more about how we’re pushing the boundaries of science and shaping the future of life sciences !
DNA Script a republié ceci
This week, DNA Script is proud to sponsor NERLSCD 2024 in Albany, New York. If you are attending, please stop by our booth to learn about the latest developments in #enzymatic #DNA synthesis. I look forward to seeing you there! #dnasynthesis #oligos #abrf
We're super excited to be attending Canada SynBio 2024 in Toronto, Oct 7-9. Stop by our booth to ask how enzymatic DNA synthesis can help your projects. #SynBio2024 https://lnkd.in/gakNxKFb
Come and join our team: https://lnkd.in/eUBVGKMU
Viral infection in fruit flies can alter intestinal homeostasis and lead to physiological changes. Researchers from Institut Pasteur and Institut Curie in Paris employed fluorescently labeled #DNA #oligonucleotides printed by enzymatic DNA synthesis (#EDS) to track viral infection of the fruit fly gut using a technique called RNA FISH. The group found that infection of flies with the Drosophila A virus (DAV) led to changes in intestinal homeostasis, including an over-proliferation of intestinal stem cells (ISCs). The group found that DAV infection caused cytokine release through a JNK signaling pathway, leading to ISC proliferation through growth factor signaling pathways. Sting-Relish NF-κB signaling was found to be required for the ISC proliferation, and the over-proliferation of ISC cells within the fruit fly #gut led to a shortened #lifespan. A marker for age-associated intestinal dysplasia was upregulated in infected flies. This research highlights how viral infection affects intestinal physiology and revealed important interactions between immune pathways, gut physiology, and aging. #DNAprobes #aging #fruitfly Viral infection disrupts intestinal homeostasis via Sting-dependent NF-κB signaling in Drosophila: Current Biology (cell.com)
#Apoptosis, or programmed cell death, is a mechanism by which the body may eliminate unnecessary, dysfunctional or highly damaged cells. One mechanism of triggering apoptosis involves the clustering of death receptors on the cell surface. A team at the Karolinska Institutet in Stockholm, Sweden recently published a study in which #DNA origami was used as a switchable control to induce apoptosis in #cancer. Reporting in the journal Nature Nanotechnology, the researchers created a DNA origami which contains ligands that, when exposed, bind and cluster death receptors together, triggering cell death. Under the slightly basic pH conditions of normal cells, the ligands are hidden. However in the lower pH conditions of a solid tumor, the ligands are exposed, causing tumor cells to die. The approach was used in mice containing human breast cancer #xenografts and showed up to a 70% reduction in tumor growth. This approach holds promise as a DNA-based method for treating solid tumors in humans. #syntheticbiology #therapeutics #oligonucleotides https://lnkd.in/dWVr-wDj
Science and Technology were featured during the VivaTech 2024 week, Europe's biggest annual start-up event. Biotech companies were represented alongside DNA Script, and we were happy to celebrate other companies joining the French Tech ranking for 2024, including TreeFrog Therapeutics ImCheck Therapeutics Ÿnsect Innovafeed DNA Script is excited that VivaTech captured the next innovations and trends, by putting light on new and exciting R&D developments in Europe and around the world such as AI & biosecurity, bioprinted skin, gene synthesis, and cell-based therapies. #DNAsynthesis #DNAondemand Viva Technology La French Tech Marina Ferrari Clara Chappaz