OZ Biosciences

Trick or Treat! Happy Halloween from OZ Biosciences' team

We're delighted to introduce Tom, our newest team member at OZ Biosciences 🎆 🎉 Tom joins us as a Formulation Scientist in Marseille, France. 🚀 His mission is to develop and support the formulation platform especially lipid nanoparticles (LNP), polymeric nanoparticles (PNP) and all other nanoparticles-based delivery systems such as liposome, lipoplexes or polyplexes. He is dedicated to execute a skilled and innovative research. 💼 🌟 Please join us in welcoming Tom to the OZ Biosciences family! 🎈 Florent Poulhès, Sofia Slaoui, Sophie Hubert, Elise Bonvin, Antonin Vinck, Mélanie Le Clech, Chloé De Vita, Tom Roussel #ozbiosciences, #magnetofection, #transfection, #transduction, #bioproduction, #mRNA, #LNP, #nanoparticles, #nanosciences, #polymers

🎓 Scientific Highlight of the Week 🎓 We are happy to share insights from a genuine study entitled "RNA G-quadruplexes form scaffolds that promote neuropathological a-synuclein aggregation" published in Cell by Kazuya Matsuo et al: https://lnkd.in/dY_Xfw8w Congratulations to all authors for this great article. They demonstrate that RNA G-quadruplex assembly forms scaffolds for a-synuclein aggregation, contributing to neurodegeneration. The administration of 5-aminolevulinic acid, a protoporphyrin IX prodrug, prevents RNA G-quadruplex phase separation, thereby attenuating a-synuclein aggregation, neurodegeneration, and progressive motor deficits in a-synuclein preformed fibril-injected synucleinopathic mice. Our NeuroMag transfection reagent (Magnetofection) was used to transfect primary mouse cortical neurons. Sefan Asamisu, Hiroyoshi Suzuki, Atsushi Takeda #neuromag, #transfection, #neurons, #cortical, #parkinson, #dementia, #lewisbodies, #atrophy, #neurodegeneration, #neurosciences

October is Breast Cancer Awareness Month, a time to reflect on the critical importance of scientific advancements in the fight against this pervasive disease. OZ Biosciences is proud to contribute to these advancements, continuously striving to develop innovative solutions in cancer research. Together, through relentless dedication and cutting-edge technology, we move closer to a future where cancer can be effectively treated and ultimately eradicated. 💗 #BreastCancerAwareness, #OZBiosciences, #Research, #Innovation, #Hope

🎓 Scientific Highlight of the Week 🎓 We are delighted to share insights from a genuine study entitled "Activation of osmo-sensitive LRRC8 anion channels in macrophages is important for micro-crystallin joint inflammation" published in Nature Comm by Twinu Wilson Chirayath et al: https://lnkd.in/gaB_v4q7 Congratulations to all authors for this great article. They find that activation of the NLRP3 inflammasome by crystals and concomitant production of IL-1β depend on cell volume regulation via activation of the osmo-sensitive LRRC8 anion channels and they identify a function of the LRRC8 osmo-sensitive anion channels with pathophysiological relevance in the context of joint crystal-induced inflammation. Our Lentiblast premium (viral enhancers) was used to boost lentivral transduction in THP-1 cells. Twinu wilson Chirayath PhD, Matthias Ollivier, Mete Kayatekin, Jonas Friard, Hélène Hirbec, Christelle COMBE, Mylène Zarka, Frédéric Lioté, Francois Rassendren, Hang-Korng Ea #lentivirus, #ozbiosciences, #transduction, #viralenhancers, #macrophage, #anionchannel, #inflammation, #cytokines, #inflammasome

We're very happy to introduce Payton, our newest team member at OZ Biosciences USA 🎆 🎉 Payton joins us as a Sales Assistant in San Diego, California USA. 🚀 Her mission is to support existing customers and prospects. She is committed to set up a strong and excellent customer relationships. 💼 🌟 Please join us in welcoming Payton to the OZ Biosciences family! 🎈 Payton Aull, Joanna Klopotowski, Justin Morsch, Sami Mamarbashi #ozbiosciences, #magnetofection, #transfection, #transduction, #bioproduction, #mRNA, #LNP

New Products: Lipid Nanoparticles Selection Kits allowing you to select among 3 or 5 different LNP formulations, the one that works best in your model. Please visit our website to find more details: https://lnkd.in/du-tFh4v #LNP, #mRNA, #formulation, #delivery, #nanoparticles, #lipids, #nanosciences, #vaccines

🎓 Scientific Highlight of the Week 🎓 We are delighted to share insights from a brand-new study entitled "Modeling memory B cell responses in a lymphoid organ-chip to evaluate mRNA vaccine boosting" published in J. Exp. Med by Raphaël Jeger-Madiot et al:  https://lnkd.in/dydxf_Rw Congratulations to all authors for this impressive study. They developed a lymphoid organ-chip (LO chip) model to predict the immunogenicity of candidate vaccines and demonstrated that the LO chip represents a versatile platform suited to the preclinical evaluation of vaccine-boosting strategies. Our LNP formulations engineered with a “Moderna-like” lipid composition and encapsulating mRNA encoding for GFP ad Ovalbumine were used as controls. Raphaël Jeger-Madiot, Delphine Planas, isabelle STAROPOLI, Hippolyte Debarnot, Jérôme Kervevan, Héloïse MARY, Camilla Collina, Barbara Fonseca, Rémy ROBINOT, Stacy Gellenoncourt, Olivier Schwartz, Lorna Ewart, Michael Bscheider, Lisa Chakrabarti #mRNA, #vaccine, #immunology, #LNP, #immunization, #chips, #lymphoidorganchip

We're very happy to introduce Justin, our newest team member at OZ Biosciences 🎆 🎉 Justin joins us as a Technical Sales Specialist in San Diego, California USA. 🚀 His mission is to give exceptional customer support service to our clients including technical support for transfection, transduction, bioproduction. He will commit to build and maintain a strong customer relationships. 💼 🌟 Please join us in welcoming Justin to the OZ Biosciences family! 🎈 #ozbiosciences, #magnetofection, #transfection, #transduction, #bioproduction

We're delighted to introduce Tinnah, our newest team member at OZ Biosciences 🎉 Tinnah joins us as a Sales Administration Manager in Marseille, France. She will play a role in running the growth and expansion of our business. 🚀 Her mission is to provide exceptional service to our clients, to build and maintain strong relationships through continuous consultation, ensuring that our clients' needs are not just met, but exceeded. 💼 🌟 Please join us in welcoming Tinnah to the OZ Biosciences family! 🎈 #NewTeamMember hashtag #WelcomeSami hashtag #OZBiosciencesFamily