Redox Medicine Society

Nicotinamide Riboside and Reactive Species Interactome: New Pathways in Alzheimer’s Disease Therapy! A new research, led by Amalia Dolga, University of Groningen Medical Center, investigated the impact of Nicotinamide Riboside (NR) and the Reactive Species Interactome (RSI) on neurodegenerative conditions. The study, in collaboration with the National Institute on Aging (NIA), University of Copenhagen (Københavns Universitet), and the ISTCT CNRS-Université de Caen UMR 6030, reveals that NR not only prevents neuronal ferroptosis but also modulates crucial biochemical pathways in the brain. The findings highlight new, region-specific proteomic changes and offer promising insights into disease modification and therapeutic strategies. Dr. Laurent Chatre, co-author and active member of the RMS Scientific Board, commented on the study, noting, “This paper opens up new perspectives on Alzheimer’s Disease, well beyond the traditional beta-amyloid-centered view, which has ultimately not led to therapeutic breakthroughs. The RSI and mitochondria are key players in this disease, presenting new opportunities for biomarkers, therapeutic targets, and personalized medicine". 🔗 Read more: https://lnkd.in/deVzxbVj. #RedoxMedicineSociety #RedoxMedicine2024 #redox #rms #alzheimersdisease #reactivespeciesinteractome #neuroscience #innovation #personalizedmedicine

Michał Żebrowski's innovative research on metallofulleronols has earned him the Best Poster Presentation award at Redox Medicine 2024! 🏆 His study presents a new generation of radiotherapeutics aimed at protecting human erythrocytes from radiolytically induced hemolysis, a critical concern in radiotherapy. Representing the University of Warsaw, Poland, Michał explored how metallofulleronols can serve as effective radioprotective agents. By mitigating the damage caused by radiation to red blood cells, these compounds have the potential to significantly improve the safety and effectiveness of cancer treatments. His findings suggest that metallofulleronols could play a crucial role in enhancing patient outcomes by reducing the adverse side effects associated with radiotherapy. 🔗 Learn more about the award-winning talks: https://lnkd.in/d-xXn85p. 🔁 Missed the conference? Watch the replay and follow up with the award-winning talks. 🌐: https://lnkd.in/dkNzFQZU #RedoxMedicineSociety #RedoxMedicine2024 #redox #rms #metallofulleronols #radiotherapeutics #radioprotection #hemolysis #cancertreatment

Congratulations to Sofia Masini on winning the Best Poster Presentation at Redox Medicine 2024! 🏆 Her innovative research on the antiviral and anti-inflammatory properties of a synthetic thiol molecule is a significant step forward in understanding and potentially treating respiratory viral infections. Sofia Masini, Università degli Studi di Urbino Carlo Bo, Italy, presented her work on a novel thiol-based molecule (I-152) that releases N-Acetyl-L-Cysteine (NAC) and Cysteamine (MEA). Her research focuses on how redox state alterations affect antiviral and inflammatory responses, a critical area given the role of redox imbalances in respiratory virus infections. 🔗 Learn more about the award winning talks: https://lnkd.in/d-xXn85p. 🔁 Missed the conference? Watch the replay and follow up with the award winning talks. 🌐: https://lnkd.in/dkNzFQZU. #RedoxMedicineSociety #RedoxMedicine2024 #redox #rms #thiol #syntheticthiol #oxidativestress #antiviralactivity #antiinflammatory #endothelialfunction

Breakthrough in COVID-19 Research by Rosangela Silva Santos (USP - Universidade de São Paulo) Awarded Best Short Oral Presentation at Redox Medicine 2024 🏆! Dr. Silva Santos's research at the University of São Paulo revealed that arachidonic acid (AA) treatment significantly increases PGF2α production in SARS-CoV-2 permissive lung cells. This suggests a crucial role for PGF2α in COVID-19 pathophysiology. Dr. Santo's results could pave the way for new therapeutic approaches in COVID-19 and other inflammatory diseases. 🔗 Learn more about the award-winning talks: https://lnkd.in/dZ452-XT 🔁 Missed the conference? Watch the replay and follow up with the award-winning talks. https://lnkd.in/dEqDyhHF 🌐: https://lnkd.in/dsCEQThq #RedoxMedicineSociety #RedoxMedicine2024 #redox #rms #ArachidonicAcid #Oxylipins #COVID19 #AwardWinner #LungHealth #InflammationResearch

🔁 Now is your chance to catch up if you missed Redox Medicine 2024! For the period of 3 weeks, access the full conference replay and immerse yourself in over 50 expert presentations and discussions. 📄 Have another look at the agenda to see all the topics covered: https://lnkd.in/d2Ed-8ra Stay ahead in your field by exploring the latest advancements in redox medicine. Don't miss this exclusive opportunity! ⏯ Access the replay today: https://lnkd.in/dEqDyhHF #RedoxMedicieSociety #RedoxMedicine2024 #biomarkers #redoxbiology #redox #antioxidants #innovation #oxidativestress #RedoxResearch

Synthetic Thiol Compounds Transform Endothelial Cell Dynamics  by Michela Bruschi, Awarded Best Short Oral Presentation at Redox Medicine 2024 🏆 ! Dr. Bruschi studied how synthetic thiol compounds affect endothelial cell redox modulation, metabolic profiles, and stress responses in varying oxygen levels. This research shows their potential to regulate cellular redox states, offering new therapeutic approaches for endothelial dysfunction. In her work at the University of Urbino, she focuses on fine-tuning cellular redox states with synthetic thiol compounds to address oxidative challenges like hypoxia or inflammation. Her findings could pave the way for future therapies in disease and aging. 🔗 Learn more about the award winning talks: https://lnkd.in/dZ452-XT 🔁 Missed the conference? Watch the replay and follow up with the award winning talks. 🌐: https://lnkd.in/dsCEQThq #RedoxMedicineSociety #RedoxMedicine2024 #redox #rms #thiol #syntheticthiol #oxidiativestress #AwardWinner #EndothelialFunction

#RedoxMedicine Scientific Contribution Award: Tamara Tomin, Technische Universität Wien, Austria! 🏆 Congratulations to Dr. Tomin on her winning presentation, "Metabolic Regulation by Redox Signaling in the Heart," and her important contributions to the conference. Dr. Tomin's research focuses on the impact of oxidative stress on cardiac metabolism, highlighting the role of oxidative modifications (oxPTMs) on metabolic enzymes. Her study identified pyruvate kinase M (PKM) as particularly sensitive to these modifications, with implications for heart failure treatment. ⏯ Learn more about her data in the Redox Medicine 2024 Replay and Abstracts Book. #RedoxMedicieSociety #RedoxMedicine2024 #biomarkers #redoxbiology #redox #antioxidants #innovation #oxidativestress #RedoxResearch

Wrapping Up Redox Medicine 2024 with Martin Feelisch! Martin Feelisch, an active member of the Redox Medicine Society from the University of Southampton, concluded the event by reflecting on the current advancements and future directions in redox medicine. His experience and perspective provided a comprehensive overview of the transformative potential in this field. Thank you for your contributions and we look forward to the continued progress and innovation in redox research. #RedoxMedicieSociety #RedoxMedicine2024 #biomarkers #redoxbiology #redox #antioxidants #innovation #oxidativestress #RedoxResearch

Investigating PGF2α Production in SARS-CoV-2 Permissive Human Lung Epithelial Cells Rosangela Silva Santos, USP - Universidade de São Paulo, Brazil, presented her work at #RedoxMedicine2024, via a short oral presentation. Her study investigates the preferential production of PGF2α in SARS-CoV-2 permissive human lung epithelial cells. This research provides crucial insights into the virus's impact on lung tissue and may inform future therapeutic strategies for COVID-19. #RedoxMedicieSociety #RedoxMedicine2024 #biomarkers #redoxbiology #redox #antioxidants #innovation #oxidativestress #RedoxResearch

Oxidative Stress, Placenta, Zika Virus: Exploring the Therapeutic Potential of Natural Products Marilia Goulart, Federal University of Alagoas - UFAL, Brazil, presented interesting data during #RedoxMedicine2024. Her study explains relationship between oxidative stress, the placenta, and the Zika virus, while also highlighting the therapeutic potential of natural products. #RedoxMedicieSociety #RedoxMedicine2024 #biomarkers #redoxbiology #redox #antioxidants #innovation #oxidativestress #RedoxResearch