Metabelly

🧠 𝗦𝘁𝘂𝗱𝘆 𝗟𝗶𝗻𝗸𝘀 𝗗𝗮𝗶𝗹𝘆 𝗣𝗿𝗼𝗯𝗶𝗼𝘁𝗶𝗰𝘀 𝗮𝗻𝗱 𝗖𝗼𝗴𝗻𝗶𝘁𝗶𝘃𝗲 𝗛𝗲𝗮𝗹𝘁𝗵 🧠 A recent study published in Nutrients examined the association between 𝗱𝗮𝗶𝗹𝘆 𝗽𝗿𝗼𝗯𝗶𝗼𝘁𝗶𝗰 𝗳𝗼𝗼𝗱 𝗰𝗼𝗻𝘀𝘂𝗺𝗽𝘁𝗶𝗼𝗻 (𝘀𝘂𝗰𝗵 𝗮𝘀 𝘆𝗼𝗴𝘂𝗿𝘁 𝗮𝗻𝗱 𝗳𝗲𝗿𝗺𝗲𝗻𝘁𝗲𝗱 𝗱𝗮𝗶𝗿𝘆) and 𝗰𝗼𝗴𝗻𝗶𝘁𝗶𝘃𝗲 𝗳𝘂𝗻𝗰𝘁𝗶𝗼𝗻 𝗮𝗺𝗼𝗻𝗴 𝗼𝗹𝗱𝗲𝗿 𝗮𝗱𝘂𝗹𝘁𝘀 in the U.S., based on data from the National Health and Nutrition Examination Survey (NHANES). 𝗛𝗲𝗿𝗲’𝘀 𝘄𝗵𝗮𝘁 𝘁𝗵𝗲𝘆 𝗳𝗼𝘂𝗻𝗱: • 𝗘𝗻𝗵𝗮𝗻𝗰𝗲𝗱 𝗖𝗼𝗴𝗻𝗶𝘁𝗶𝘃𝗲 𝗙𝘂𝗻𝗰𝘁𝗶𝗼𝗻: Participants consuming probiotics daily scored better on the Digit-Symbol Substitution Test (DSST), a measure of cognitive abilities like memory, attention, and visual perception. • 𝗜𝗺𝗽𝗮𝗰𝘁 𝗼𝗳 𝗣𝗿𝗼𝗯𝗶𝗼𝘁𝗶𝗰𝘀: While unadjusted models showed a significant association, the results showed only a trend when adjusted for age, education, and income—highlighting the need for further studies to confirm the effect. • 𝗣𝗼𝘁𝗲𝗻𝘁𝗶𝗮𝗹 𝗳𝗼𝗿 𝗔𝗴𝗶𝗻𝗴 𝗣𝗼𝗽𝘂𝗹𝗮𝘁𝗶𝗼𝗻𝘀: Probiotics could offer a low-cost dietary strategy for supporting cognitive health in ageing populations, potentially delaying cognitive decline and associated healthcare costs. This study supports the growing evidence linking gut health and brain function, emphasizing the importance of simple dietary choices. However, researchers stress that further investigation is needed to clarify if probiotics directly impact cognitive health and to explore this association in other demographics. https://lnkd.in/dk2kRJ7f #CognitiveHealth #Probiotics #AgingWell #NutritionScience #GutBrainConnection

🧠🌱 𝗡𝗲𝘄 𝗜𝗻𝘀𝗶𝗴𝗵𝘁𝘀 𝗶𝗻𝘁𝗼 𝘁𝗵𝗲 𝗚𝘂𝘁-𝗕𝗿𝗮𝗶𝗻 𝗖𝗼𝗻𝗻𝗲𝗰𝘁𝗶𝗼𝗻 𝗶𝗻 𝗣𝗮𝗿𝗸𝗶𝗻𝘀𝗼𝗻'𝘀 𝗗𝗶𝘀𝗲𝗮𝘀𝗲 🌱🧠 New research has revealed crucial links between the gut microbiome and early stages of Parkinson's disease (PD). The study found significant differences in both the gut and oral microbiomes of early-stage PD patients, suggesting that the gut-brain axis plays a key role in disease development. 🔍 𝗞𝗲𝘆 𝗧𝗮𝗸𝗲𝗮𝘄𝗮𝘆𝘀: • 𝗚𝘂𝘁 𝗠𝗶𝗰𝗿𝗼𝗯𝗶𝗼𝗺𝗲: PD patients showed increased microbial diversity compared to healthy controls. 16 bacterial species, including Streptococcus mutans and Bifidobacterium dentium, were overrepresented in PD patients, while 28 species were underrepresented. A notable disruption in microbial networks, especially among short-chain fatty acid producers, was observed. • 𝗢𝗿𝗮𝗹 𝗠𝗶𝗰𝗿𝗼𝗯𝗶𝗼𝗺𝗲: The study revealed distinct oral microbiome profiles in PD patients, particularly elevated levels of oral pathogens. These findings suggest a potential link between oral health and neurodegeneration, highlighting the importance of oral microbiome health in Parkinson's disease. 🧬 Advanced Tools like shotgun metagenomics and machine learning were used to identify these microbiome shifts. These findings pave the way for new diagnostic biomarkers and offer potential treatment avenues. This research demonstrates the critical role of the gut-brain axis in neurodegenerative diseases and highlights the possibility of using oral microbiome markers for early diagnosis of Parkinson's before motor symptoms appear. 👩🔬👨🔬 Study by: A collaboration between 23andMe and Montana State University, involving over 445 PD patients and 221 controls. https://lnkd.in/d8V6xJpE hashtag #ParkinsonsResearch #MicrobiomeScience #Neurodegeneration #GutBrainAxis #PrecisionMedicine #ScientificBreakthrough #ResearchInnovation

🔬 𝗥𝗶𝗯𝗼𝗳𝗹𝗮𝘃𝗶𝗻 𝗮𝗻𝗱 𝘁𝗵𝗲 𝗠𝗶𝗰𝗿𝗼𝗯𝗶𝗼𝗺𝗲: 𝗘𝗺𝗽𝗼𝘄𝗲𝗿𝗶𝗻𝗴 𝗪𝗼𝗺𝗲𝗻'𝘀 𝗛𝗲𝗮𝗹𝘁𝗵 🔬 Recent research sheds light on the importance of 𝗿𝗶𝗯𝗼𝗳𝗹𝗮𝘃𝗶𝗻 (𝗩𝗶𝘁𝗮𝗺𝗶𝗻 𝗕𝟮) for women’s health, emphasizing its vital role in supporting energy metabolism, antioxidant defense, and hormonal balance. ✨ Women, especially during pregnancy and lactation, have increased riboflavin demands. Riboflavin helps in DNA synthesis, iron metabolism, and neural tube formation in the fetus. 🧬 What’s exciting is the potential 𝘀𝘆𝗻𝗲𝗿𝗴𝘆 𝗯𝗲𝘁𝘄𝗲𝗲𝗻 𝗿𝗶𝗯𝗼𝗳𝗹𝗮𝘃𝗶𝗻 𝗮𝗻𝗱 𝗽𝗿𝗼𝗯𝗶𝗼𝘁𝗶𝗰𝘀! Specific Lactobacillus strains produce riboflavin, combining its benefits with gut and vaginal health promotion. This opens the door to innovative probiotics for better women's health outcomes. 🌱 Riboflavin-producing bacteria could offer a more natural way to meet riboflavin needs, especially as over 30% of women worldwide suffer from deficiencies, impacting fertility, pregnancy, and overall well-being. Let’s continue exploring how microbiome-based solutions can address micronutrient deficiencies and enhance women’s health! 🌿💪 https://lnkd.in/dd6-V7JN #Riboflavin #VitaminB2 #Microbiome #WomensHealth #Probiotics #Nutraceuticals #GutHealth #HormonalBalance #ScienceNews #WomenInScience

Today, we bring you impressions from the Startup Europe Regatta featuring familiar faces from our community ⭐ as well as some newly discovered ones 🔥 Enjoy 😊 Ivan Jukić, ScanEat, Ivan Bracic, Ena Melvan, Metabelly, Codeasy, Anto Širić, sportreact 💖

𝗚𝘂𝘁 𝗠𝗶𝗰𝗿𝗼𝗯𝗶𝗼𝗺𝗲 𝗮𝗻𝗱 𝗜𝗿𝗼𝗻 𝗢𝘃𝗲𝗿𝗹𝗼𝗮𝗱 𝗶𝗻 β-𝗧𝗵𝗮𝗹𝗮𝘀𝘀𝗲𝗺𝗶𝗮 𝗣𝗮𝘁𝗶𝗲𝗻𝘁𝘀: 𝗔 𝗡𝗲𝘄 𝗜𝗻𝘀𝗶𝗴𝗵𝘁 A recent study published in Scientific Reports sheds light on the significant alterations in gut microbiota in β-thalassemia patients and its correlation with iron overload. β-Thalassemia is a hereditary blood disorder requiring frequent blood transfusions, leading to iron overload and potential gut dysbiosis. This study analyzed the gut microbiomes of 70 β-thalassemia/HbE patients and 30 healthy controls, revealing key differences: 🔬 𝗞𝗲𝘆 𝗙𝗶𝗻𝗱𝗶𝗻𝗴𝘀: • Patients exhibited less diverse microbiota, with a higher prevalence of harmful bacteria like Clostridium and Enterobacteriaceae. • Healthy controls had a higher abundance of beneficial, short-chain fatty acid (SCFA)-producing bacteria such as Alistipes and Coprococcus, which promote gut health and inflammation control. • Higher ferritin (iron) levels were linked to a higher abundance of harmful gut bacteria, contributing to systemic inflammation and potential infections. • These findings emphasize the crucial role of the gut microbiome in β-thalassemia management and offer potential pathways for developing microbiome-based diagnostics and therapies. 👩🔬 Conducted at Mahidol University, Thailand, this research opens up exciting possibilities for targeting the gut microbiota to mitigate complications from iron overload. For more details, check out the full study here https://lnkd.in/d4Q5j7Gx . #Microbiome #Thalassemia #GutHealth #IronOverload #ScientificResearch #BetaThalassemia #Healthcare

We want to thank all the fantastic startups that exhibited at StartupExpo2024 on the beautiful waterfront in Split! Your innovative solutions and passion for entrepreneurship made this event an incredible experience for all participants. Seeing how each idea and project brought new energy and potential for change was inspiring! Thank you for sharing your visions with us and engaging the community. We look forward to future collaborations and will follow your successes! Together we create a better future! 🚀💙 #StartupExpo #StartupEuropeRegatta #InnovationFutureForum sportreact, VeeMee, Silver technologies, Grid ONE, CROTEH Ltd - Sustainable Technologies Development Centre, Voxares, AymoLive, SplxAI, Agilos IT, GUIDE B, Sailboat RC, EdukaCentar Zagreb, MARTEHINK, Metabelly, WORKSPACE, Earthbound , Zeinet&SSE LLP, BlueDataB, , FACEPLATE, Maistral, VIS

🌿 𝗜𝗺𝗽𝗮𝗰𝘁 𝗼𝗳 𝗗𝗶𝗲𝘁 𝗼𝗻 𝗩𝗮𝗴𝗶𝗻𝗮𝗹 𝗠𝗶𝗰𝗿𝗼𝗯𝗶𝗼𝗺𝗲 𝗗𝘂𝗿𝗶𝗻𝗴 𝗣𝗿𝗲𝗴𝗻𝗮𝗻𝗰𝘆 🌿 A recent study from the University of Hawai'i sheds light on how diet quality affects the vaginal microbiome throughout pregnancy, focusing on a multi-ethnic cohort. 🦠 𝗞𝗲𝘆 𝗙𝗶𝗻𝗱𝗶𝗻𝗴𝘀: • Higher intake of carbohydrates was linked to increased levels of beneficial 𝘓𝘢𝘤𝘵𝘰𝘣𝘢𝘤𝘪𝘭𝘭𝘶𝘴 𝘤𝘳𝘪𝘴𝘱𝘢𝘵𝘶𝘴 and 𝘓. 𝘨𝘢𝘴𝘴𝘦𝘳𝘪, while lower intake was associated with more 𝘓. 𝘪𝘯𝘦𝘳𝘴 and anaerobic species such as 𝘎𝘢𝘳𝘥𝘯𝘦𝘳𝘦𝘭𝘭𝘢 𝘷𝘢𝘨𝘪𝘯𝘢𝘭𝘪𝘴. • Diet quality, measured using the 𝗛𝗲𝗮𝗹𝘁𝗵𝘆 𝗘𝗮𝘁𝗶𝗻𝗴 𝗜𝗻𝗱𝗲𝘅 (𝗛𝗘𝗜-𝟮𝟬𝟭𝟱), showed that better diet adherence promotes a healthier vaginal microbiome, potentially improving pregnancy outcomes. 🧪 𝗦𝘁𝘂𝗱𝘆 𝗗𝗲𝘁𝗮𝗶𝗹𝘀: • Participants: 40 pregnant women from four major ethnic groups in Hawai'i (Japanese, Filipino, Native Hawaiian, and Non-Hispanic White). • Methods: Vaginal swabs collected each trimester, analyzed using 16s rRNA sequencing. 🔍 𝗪𝗵𝘆 𝗜𝘁 𝗠𝗮𝘁𝘁𝗲𝗿𝘀: A well-balanced diet, rich in carbohydrates, may enhance the growth of beneficial bacteria during pregnancy, supporting better reproductive health. This research highlights how small dietary adjustments can lead to significant health benefits for expecting mothers. https://lnkd.in/dtjUJKyU #GutHealth #PregnancyHealth #Microbiome #NutritionScience #WomensHealth #VaginalMicrobiome #HealthyPregnancy

🧬 𝗖𝗮𝗻 𝗣𝗲𝗿𝘀𝗼𝗻𝗮𝗹𝗶𝘇𝗲𝗱 𝗣𝗿𝗲𝗯𝗶𝗼𝘁𝗶𝗰𝘀 & 𝗣𝗿𝗼𝗯𝗶𝗼𝘁𝗶𝗰𝘀 𝗥𝗲𝗹𝗶𝗲𝘃𝗲 𝗜𝗕𝗦? 🧬 A study from 𝘕𝘶𝘵𝘳𝘪𝘦𝘯𝘵𝘴 explores how personalized supplements can help manage 𝗜𝗿𝗿𝗶𝘁𝗮𝗯𝗹𝗲 𝗕𝗼𝘄𝗲𝗹 𝗦𝘆𝗻𝗱𝗿𝗼𝗺𝗲 (𝗜𝗕𝗦). The study, conducted 𝗮𝗰𝗿𝗼𝘀𝘀 𝟮𝟭 𝗺𝗲𝗱𝗶𝗰𝗮𝗹 𝗰𝗲𝗻𝘁𝗲𝗿𝘀 𝗶𝗻 𝗝𝗮𝗽𝗮𝗻, involved 120 patients and tailored supplements to each individual’s gut microbiota and IBS subtype (Diarrhea, Constipation, Mixed). 🔑 Key Results: • 𝗜𝗕𝗦-𝗗 (𝗗𝗶𝗮𝗿𝗿𝗵𝗲𝗮-𝘁𝘆𝗽𝗲): Symptoms improved by 𝟰𝟰.𝟱 points 📉 • 𝗜𝗕𝗦-𝗖 (𝗖𝗼𝗻𝘀𝘁𝗶𝗽𝗮𝘁𝗶𝗼𝗻-𝘁𝘆𝗽𝗲): A whopping 𝟱𝟭.𝟮-point improvement in severity, plus increased stool frequency 🚽 Overall: All patients saw a 𝟯𝟴-𝗽𝗼𝗶𝗻𝘁 reduction in IBS severity. 💡 𝗪𝗵𝗮𝘁 𝗱𝗼𝗲𝘀 𝘁𝗵𝗶𝘀 𝗺𝗲𝗮𝗻? Personalized gut health treatments may offer significant relief, especially for those struggling with IBS-D or IBS-C. Is it time to explore tailored prebiotic and probiotic solutions for gut health? 🌿🧪 https://lnkd.in/dyHt9dFK #GutHealth #Microbiome #IBSRelief #PersonalizedMedicine #Prebiotics #Probiotics

🧠 𝗖𝗮𝗻 𝗕𝗮𝗰𝘁𝗲𝗿𝗶𝗮 𝗮𝗻𝗱 𝗙𝘂𝗻𝗴𝗶 𝗶𝗻 𝗢𝘂𝗿 𝗕𝗿𝗮𝗶𝗻𝘀 𝗖𝗼𝗻𝘁𝗿𝗶𝗯𝘂𝘁𝗲 𝘁𝗼 𝗡𝗲𝘂𝗿𝗼𝗱𝗲𝗴𝗲𝗻𝗲𝗿𝗮𝘁𝗶𝘃𝗲 𝗗𝗶𝘀𝗲𝗮𝘀𝗲𝘀? 🦠 Research suggests that microorganisms, including bacteria and fungi, may inhabit the brain and play a role in neurodegenerative diseases such as 𝗔𝗹𝘇𝗵𝗲𝗶𝗺𝗲𝗿'𝘀, 𝗣𝗮𝗿𝗸𝗶𝗻𝘀𝗼𝗻'𝘀, 𝗮𝗻𝗱 𝗠𝘂𝗹𝘁𝗶𝗽𝗹𝗲 𝗦𝗰𝗹𝗲𝗿𝗼𝘀𝗶𝘀. This "brain microbiome" challenges the long-held belief that the brain is a sterile environment, free of microbial life. 🔍 In a review published in Frontiers in Aging Neuroscience, researchers explored how these microbes could contribute to diseases. The brain microbiome hypothesis suggests that bacteria like Chlamydia pneumoniae, Helicobacter pylori, and fungi such as Candida and Malassezia, may induce chronic neuroinflammation, possibly accelerating disease progression. But there’s still much debate, with some studies finding no microbial link to these conditions. 🚨 𝗞𝗲𝘆 𝗛𝗶𝗴𝗵𝗹𝗶𝗴𝗵𝘁𝘀: • Microorganisms like bacteria and fungi have been found in the brains of patients with neurodegenerative diseases. • These microbes may lead to neuroinflammation, a key factor in diseases like Alzheimer’s and Parkinson’s. • The theory faces challenges, such as contamination in research and conflicting results across studies. • This fascinating research pushes the boundaries of how we think about brain health and its connection to the broader microbiome. Could understanding and manipulating the brain microbiome offer new hope for treatment? https://lnkd.in/dp64TuQ9 #Neuroscience #Microbiome #BrainHealth #Alzheimers #Parkinsons #NeurodegenerativeDiseases #Research #GutBrainAxis #Innovation

🧠 𝗚𝘂𝘁 𝗠𝗶𝗰𝗿𝗼𝗯𝗶𝗼𝗺𝗲 𝗮𝗻𝗱 𝗔𝘀𝗽𝗶𝗿𝗶𝗻: 𝗡𝗲𝘄 𝗛𝗼𝗽𝗲 𝗳𝗼𝗿 𝗛𝗼𝗿𝗺𝗼𝗻𝗮𝗹 𝗜𝗺𝗯𝗮𝗹𝗮𝗻𝗰𝗲 Researchers at the Francis Crick Institute have made a fascinating discovery! They’ve found that the gut microbiome and aspirin may offer new treatments for hypopituitarism, a condition where the pituitary gland doesn't produce enough hormones, often caused by 𝗺𝘂𝘁𝗮𝘁𝗶𝗼𝗻𝘀 𝗶𝗻 𝘁𝗵𝗲 𝗦𝗼𝘅𝟯 𝗴𝗲𝗻𝗲. 🔬 In this study, the Sox3 gene was removed from mice, leading to: • Reduced numbers of 𝗡𝗚𝟮-𝗴𝗹𝗶𝗮 𝗰𝗲𝗹𝗹𝘀 in the brain, essential for hormone production. • Development of 𝗵𝗼𝗿𝗺𝗼𝗻𝗮𝗹 𝗱𝗲𝗳𝗶𝗰𝗶𝗲𝗻𝗰𝗶𝗲𝘀, including growth problems and infertility. 𝗞𝗲𝘆 𝗙𝗶𝗻𝗱𝗶𝗻𝗴𝘀: • 𝗔𝘀𝗽𝗶𝗿𝗶𝗻 𝘁𝗿𝗲𝗮𝘁𝗺𝗲𝗻𝘁 restored NG2-glia cells and reversed hormonal deficiencies. • 𝗖𝗵𝗮𝗻𝗴𝗲𝘀 𝗶𝗻 𝘁𝗵𝗲 𝗴𝘂𝘁 𝗺𝗶𝗰𝗿𝗼𝗯𝗶𝗼𝗺𝗲 also helped protect against these hormonal issues, suggesting a strong gut-brain connection. This groundbreaking research highlights how gut health and common medications like aspirin could play a role in managing complex hormonal disorders. 💡 What’s next? Exploring how this discovery can lead to new treatments for people with Sox3 mutations or other hormone-related conditions. https://lnkd.in/dDnmCCJu #Microbiome #HormonalHealth #GutBrainAxis #Research