An excellent article published recently in “Cell” describes the complexities of cancer as a systemic disease, and reviews the “Hallmarks of Cancer” that were proposed as a set of functional capabilities acquired by human cells as they make their way from normalcy to neoplastic growth states, more specifically capabilities that are crucial for their ability to form malignant tumors.
The article lays out a roadmap delineating a selection of overarching themes, clouds of complexity, looming on the horizon of cancer biology and medicine that, if mechanistically addressed, promise to improve patient outcomes and quality of life.
Highlighting the meaningful impact that tumor microenvironment (TME) has on treatment response, the article mentions landmark publications from Prof. Ravid Straussman (Curesponse scientific founder) and his research group, which reported tumor-type-specific bacterial and fungal communities in many solid cancer types, suggesting treatment resistance mechanism and diagnostic potential involving bacterial nucleic acids in cancer patients’ blood.
For more information regarding the cResponse, the only combined Genomic-Functional cancer precision medicine platform, maintaining the tumor microenvironment intact for sufficient time to allow for an accurate prediction of clinical outcome, please visit the “Research and Evidence” page in our website:
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