Pharmacoevidence

🚀 Exciting News! Our R package, "closeloop", has just been approved by CRAN! 🎉 Congratulations to Akanksha Sharma and Supreet Kaur, the brilliant minds behind this package, for their outstanding contributions. "closeloop" is a game-changer in the field of Network Meta-Analysis (NMA). It allows integrating single-arm observational data by calculating the distance between studies using covariate information, effectively removing heterogeneity. This innovation enhances the comprehensiveness and robustness of comparative effectiveness research. Link to the CRAN package is in the first comment. It's also available on GitHub, so please use it and provide your thoughts or raise any issues directly on GitHub. #RStats #CRAN #NetworkMetaAnalysis #ObservationalData #ComparativeEffectiveness #heor #r heoRlytics Pharmacoevidence Shubhram Pandey Barinder Singh

I've been closely following the trends in healthcare, and one standout is the increasing significance of Real-World Evidence (RWE). Here’s why RWE is becoming a game-changer: 1. Real Insights from Real Patients: Unlike traditional randomized controlled trials (RCTs), RWE studies involve real patients in real-world settings. This provides a more comprehensive view of health outcomes and patient experiences. 2. Speed and Inclusivity: RWE studies can be conducted faster and include a diverse patient population, making the data more representative and timely. 3. Regulatory Acceptance: Major health agencies like the FDA, EMA, NICE, and CADTH are recognizing the value of RWE. They've issued guidelines on its use, emphasizing data quality and transparency. 4. Impactful Case Studies: In 2021, RWE was used as primary evidence for a new indication of tacrolimus in lung transplants in the US. This marked a significant milestone, showcasing the potential of RWE in regulatory scenarios. 5. ISPOR’s Leadership: ISPOR is leading the way in promoting RWE. Their initiatives focus on transparency and good practices, ensuring RWE studies are robust and reliable. RWE is not just a trend—it's transforming healthcare by providing actionable insights and supporting better decision-making. As we continue to embrace. RWE, we can look forward to more informed and effective healthcare solutions. #Healthcare #RWE #RealWorldEvidence #ISPOR #HealthEconomics #Innovation

We had an amazing time at #ISPOR24 in Atlanta! It was a true pleasure to connect with our clients, partners, team members, old friends, and HEOR colleagues. The exchange of ideas and insights excites us about the promising collaborations and innovations ahead! Pharmacoevidence and FINGERPOST teams proudly demonstrated our strong HEOR and Market Access expertise with an impressive showcase of 11 posters and an oral podium session. Key highlights include: - Methodology Papers: Addressing utility ceilings effect issues and early Network Meta-Analysis (NMA) in Hepatitis D, presented in collaboration with Chong Kim - Oral Podium Presentation: Shubhram Pandey delivered an insightful talk on Survival Analysis: Exploring Excess Hazard Methods and Cure Models, sparking engaging discussions - Automated SLR using GPT-4 and Machine learning models: Showcasing Generative AI (GPT-4) with three case studies achieving a remarkable 95% concurrence rate with experienced Subject Matter Experts (SMEs) - SLR and NMAs: Extensive reviews on utility and prognostic factors across various disease areas, along with baseline risk regression NMAs - R-Shiny HE Modeling Platform: Demonstrating our cutting-edge health economic modeling tool, enhancing data visualization and decision-making processes Despite the short trip, we fully enjoyed exploring Atlanta’s vibrant culture and delicious cuisine. A visit to the Coke Museum is a must, featuring over 300 Coca-Cola flavors from around the world! If you go, be sure to try Fanta Watermelon (Philippines), Mezzo Mix (Germany), and Thums Up (India). A big thank you to everyone who made this event memorable. We look forward to continuing our conversations and building on these exciting opportunities! Nicola Waddell Akanksha Sharma Catherine Bacon Shubhram Pandey Gagandeep Kaur Sumeet Attri Pankaj Rai Dr. Rajdeep Kaur #HEOR #Pharma #HealthEconomics #NetworkMetaAnalysis #GenerativeAI #Pharmacoevidence #ISPOR #ISPOR24 #CokeMuseum #AtlantaAdventures

Countdown to #ISPORAnnual! We continue our strong partnership with FINGERPOST! Join us at ISPOR in Atlanta, where we'll be at Booth 807. Combining our expertise in AI, evidence generation, modeling, and market insights we can support your product launch strategies. We look forward to sharing more about our comprehensive solutions for market access, pricing, and HEOR at #ISPORannual next week. Barinder Singh Catherine Bacon Nicola Waddell

We are pleased to announce that FINGERPOST will be joining our HEOR partners, Pharmacoevidence, at ISPOR 2024 from the 5th – 8th May. Through our partnership, we bring together AI, evidence generation, payer insight, and deep market and global expertise – the optimal toolkit for launch success. Each project is supported by Strategic Advisors who have launched products for Lilly, Roche, Novartis, Otsuka, GSK, Biogen and Jazz Pharmaceuticals, and bring experience from a diverse range of indications, markets and product types. Come and meet with Catherine Bacon, Barinder Singh, Shubhram Pandey, Nicola Waddell, Akanksha Sharma at Booth #807 to discuss how we can help prepare assets for launch from the Market access, Pricing and HEOR perspective. #ISPORAnnual #MarketAccess #HEOR

Interested in learning how GPT-4 and other Gen AI tools are revolutionizing systematic literature reviews? Pharmacoevidence team will be presenting three papers focused on the transformative role of Generative AI and machine learning algorithms in evidence synthesis during ISPOR Annual 2024, Atlanta. The details are: 📅 Revolutionizing Systematic Literature Reviews: Harnessing the Power of Large Language Model (GPT-4) for Enhanced Research Synthesis 📆 Date: Monday, May 6 ⏰ Discussion Period: 12:30 PM-1:30 PM 📅 Advancing Systematic Literature Reviews: The Integration of AI-Powered NLP Models in Data Collection Processes 📆 Date: Tuesday, May 7 ⏰ Discussion Period: 12:30 PM-1:30 PM 📅 Transforming Systematic Literature Reviews: Unleashing the Potential of GPT-4, a Cutting-Edge Large Language Model, to Elevate Research Synthesis 📆 Date: Tuesday, May 7 ⏰ Discussion Period: 12:30 PM-1:30 PM Don't miss this insightful discussion on Gen AI in HEOR. Also, visit us at Pharmacoevidence Booth 807 (Near Entrance) to experience first-hand how Gen-AI is revolutionizing systematic literature reviews, ITC/NMA, and economic models. To schedule a meeting with us at ISPOR US in Atlanta, please reach out to Nicola Waddell #ISPORAnnual #ISPOR24 #Pharmacoevidence #SLR #systematicreview #literaturereview #metaanalysis #nma #HEOR #generativeai #gpt #nlp #Machinelearning Shubhram Pandey Akanksha Sharma Gagandeep Kaur Pankaj Rai Sumeet Attri Dr. Rajdeep Kaur

Heading to ISPOR US 2024 in Atlanta to present my latest research poster on "Understanding how Baseline risk affects Treatment Outcomes in Clinical Trials: Exploring Key Factors." Excited to share my findings with you all at the poster area. Don't miss the chance to meet me in person and learn more about my research. Looking forward to seeing you there! #ISPOR #clinicaltrials #researchposter #Atlanta Shubhram Pandey Barinder Singh Nicola Waddell Gagandeep Kaur

Interested in Advanced Survival Analysis? Join us at ISPOR US 2024! My colleague Shubhram Pandey will be presenting a podium titled "Enhancing Long-Term Survival Evaluation in Cost-Effectiveness Analyses: Exploring Excess Hazard Methods and Cure Models in Non-Small Cell Lung Cancer Research" 📅 Session Title: Modeling for Health Technology Assessment (HTA) 📆 Date: Tuesday, May 7, 2024 ⏰ Time: 10:15 AM - 11:15 AM Don't miss this insightful discussion on innovative methods in survival analysis. Also, visit us at Pharmacoevidence Booth 807 to experience first-hand how Gen-AI is revolutionizing HEOR. To schedule a meeting with us at ISPOR US in Atlanta, please reach out to Nicola Waddell #ISPORAnnual #ISPOR24 #Pharmacoevidence #SLR #systematicreview #metaanalysis #nma #HEOR #survivalanalysis