h2020 SUNSHINE

The EU NanoSafety Cluster is part of my worklife since more than 15 years. Today's meeting of the NSC Steering Group was for me one of the most important ever! ✨ Why? Because we NOW are challenged to put huge efforts into securing the future of R&D&I in Europe (#FP10). We will release important information about an upcoming Task Force (related to #FP10) in the next NSC Update 🙏 You can subscribe for the monthly NSC Update on NSC webpage ( www.nanosafetycluster.eu ) and join the NSC community on LinkedIn. It is free of charge and - besides the above mentioned task force - it provides information about joint #events, #sisterproject as well as the #international #collaboration items...

During #NANOTOX2024 Day 1 on 23 Sept, several partners from the HARMLESS project showcased their groundbreaking research through both oral and poster presentations. It’s inspiring to see the innovative outcomes from our collaborative efforts come to life! 👉 Oral presentations:  * Lianyong Han (Helmholtz Munich) - Title “Pathogenic dynamics of lung macrophages during injury and regeneration caused by fiber-shaped nanomaterials” * Hongyu Ren (HMGU) - Title “Linking the molecular mechanisms of alveolar macrophage cell death induced by inhaled nanoparticles with the subsequent pathological outcome” * Roland Grafström (Karolinska Institutet ) - Title “The HARMLESS Artificial Intelligence High-Throughput Screening Approach (AI-HTS) to Materials Safety Evaluation” * Verónica Dumit (Bundesinstitut für Risikobewertung) - Title “Assessing nanofiber pathogenicity through an omics-based meta-analysis” * Pekka Kohonen (KI) - NAM-focused materials safety assessment utilizing predictive toxicogenomics space (PTGS)-driven retrieval of adverse outcome pathways in transcriptomics data” * Wouter Fransman (TNO) - Title “Nano Exposure Quantifier for Safe-by-Design of Advanced Materials” 👉 Poster presentations:  * Wendel Wohlleben (BASF) - Title “ROS Activity in Carbonaceous Nanoparticles: The Influence of Surface Area and Chemistry” * Michalina Miszczak (University of Gdansk) - Title “Dynamic QSAR modeling – time-dependent models of genotoxicity for advanced materials”

What a way to end a project! Last month, DIAGONAL partners attended the 11th International Conference on NanoToxicology #NANOTOX2024, held in gorgeous Venice! 🏛️✨ It was a great success, organised jointly by us and our NMBP-16 sister projects HARMLESS and h2020 SUNSHINE, as one of our final dissemination activities! Watch the video below, created by BNN - BioNanoNet. To learn more about DIAGONAL's presentations and contributions, read our article here: https://lnkd.in/dYA_p5vZ #Nanotechnology #NanoToxicology #SSbD #Research #Sustainability #Innovation Congrats to DIAGONAL partners who gave oral presentations: Alberto Bianco CNRS Carla Martins ISQ Gunther Van Kerckhove OCSiAl Group Alicja Mikolajczyk QSAR Lab Santiago Aparicio Universidad de Burgos And those who had posters: Laura Gómez Cuadrado Universidad de Burgos Dawid Falkowski QSAR Lab Henk van Lingen Wagenigen University Santiago Aparicio Universidad de Burgos Advisory Board member Mark Wiesner of Duke University gave a keynote. Huge thanks to the organizing committee, including those from DIAGONAL Sonia Martel Martín, Carlos Rumbo Lorenzo, Beatriz L. (ICCRAM University of Burgos), Beatriz Alfaro Serrano and Susanne Resch (BNN - BioNanoNet). Further thanks to the Scientific Committee members from DIAGONAL (in addition to those already mentioned): Andreas Falk Carlos Fito (ITENE), Stefanie Prenner (Brimatech Services GmbH), and Jo Anne Shatkin (Vireo Advisors, LLC). Finally, thanks to our External Advisory Board members: Mustafa Culha (Augusta University, US), Mark Wiesner (Duke University, US), Robert Rallo (Pacific Northwest National Laboratory, US), Ramjitti Indaraprasirt (National Nanotechnology Center, TH), and Paul Westerhoff (Arizona State University, US).

We are happy to welcome Danail Hristozov as new chair of the EU NanoSafety Cluster Working Group ‘Safe and Sustainable by Design (SSbD), Innovation & Regulation’ 🤝 . Read his welcome message here: https://lnkd.in/d99Tj3PQ #eu_nsc #ssbd #newchair

🚀 NanoTox Recap Now Live! 🧬 Missed our recent NanoTox 2024 conference? Catch up with the highlights, featuring key insights, discussions, and breakthroughs in nanotoxicology🌟 📖 Read the full news article on our website: https://lnkd.in/dcTzskZa #NanoTox #Nanotechnology

Catch a glimpse of #NanoTox2024 in Venice with our video! The 11th International Conference on NanoToxicology took place September 23-25, 2024, in the historic center of #Venice at Centro Culturale Don Orione Artigianelli. The scientific conference, organised jointly by the three NMBP-16 EU funded projects DIAGONAL, HARMLESS and h2020 SUNSHINE attracted around 250 participants from research and academic institutions, as well as from industry, governmental agencies, and experts from Europe, the United States, Africa and Asia. The conference provided a valuable platform for convening leading experts focused on the challenges related to safe and sustainable multicomponent nanomaterials (MCNM) by developing novel tools for evaluating human and environmental hazards, alongside strategies for #nanomaterial characterization, classification, grouping, and read-across for risk analysis and #sustainability assessment. We are proud of our colleagues Susanne Resch and Beatriz Alfaro Serrano for co-organizing the conference alongside their great time!

📝 Call for Papers: The main scope of the special issue focused on 'Next Generation Risk and Sustainability Assessment Approaches for Advanced (Nano)materials' is to offer highlights in the field covering the challenges of applying New Approach Methodologies (NAMs) for risk assessment of safe and sustainable by design (SSbD) advanced nanomaterials (AdNMs). We encourage researchers, engineers, scientists, and students in related fields to submit their work for consideration in this special issue. 📚 Submission Guidelines: You are welcome to submit the manuscript/s using our online system at https://lnkd.in/gzYXpBAY, and please note that the reviewing process starts as soon as we receive the manuscript.    📊 Guest Editors:    🌟 Danail Hristozov, EMERGE Ltd, Bulgaria. 🌟 Tobias Stoeger, Helmholtz Zentrum München, Germany. 🌟 Carlos Rumbo Lorenzo, ICCRAM – University of Burgos, Spain. 🌟 Otmar Schmid, Helmholtz Zentrum München, Germany.   🔗Link to the 'Call for Papers': https://lnkd.in/gzWQpcrn #Nanomaterials #AdvancedMaterials #NewApproachMethodologies #NAMs #CSBJNAM, HARMLESS, h2020 SUNSHINE, DIAGONAL, EU NanoSafety Cluster

Har du interesse i risikovurdering af jernoxider ? Vi har lige publiceret et systematisk review af jernoxider og inflammation. Studiet er ledet af Aurora Moen og Håkan Wallin, fra STAMI i Norge. Jernoxider kan både være Fe (II) og Fe (III)-oxider. Hvis de er små nok, vil partikerne ved indånding deponeres i den dybe del af lungen (alveolerne), og udløse et inflammatorisk respons, som er proportionalt med det samlede overfladeareal af de lungedeponerede partikler. Det partikel-inducerede inflammatoriske respons og medfølgende akutfaserespons øger risikoen for hjertekarsygdomme. I det systematiske review har vi derfor haft fokus på at bestemme tærskelværdier for jernoxid-induceret inflammation. Sådanne tærskelværdier vil kunne danne grundlag for en eventuel helbredsbaseret grænseværdi for jernoxider. Vi identificerede 25 relevante studier. Studierne var meget heterogene i studiedesign og kvalitet og viste stor variation i identificerede tærskelværdier (no-observed-adverse-effect-concentrations eller lowest-observed- adverse-effect-concentrations). Der var dog en del studier, som havde NOAEL på 3-5 mg/m3, herunder et, som så ud til at følge OECD test guidelines. Studiet er naturligvis open access.

I really enjoyed some fantastic days in Venice at the #NanoTox2024, catching-up with so many experts and colleagues on latest developments in #nanotoxicology, #SSbD and #AdMa research 🎉 It was a great pleasure to be part of the core team organizing this scientific conference! Congratulations to DIAGONAL, HARMLESS and h2020 SUNSHINE for their final event & big thanks to everyone who joined and contributed 😊👏🥂 EU NanoSafety Cluster BNN - BioNanoNet Danail Hristozov, Tobias Stoeger, Otmar Schmid, Carlos Rumbo, Beatriz Alfaro Serrano