In Silico World

While many options for #orthopaedic insoles exist, they are often not customized for the individual patient. In this one-minute video, produced by VPH Institute and KU Leuven, you will discover how the #InSole solution uses advanced #ComputerModels simulations to achieve insoles better personalization, superior performance and correction, thus improving posture, movements, and ultimately quality of life. The InSole solution has been developed by partner KU Leuven and Materialise 📽️👇

We are excited to share a recent #publication in Briefings in Bioinformatics that highlights the advancements in in silico modeling and simulation. This work, entitled "Consensus Statement on the Credibility Assessment of Machine Learning Predictors", underscores the transformative potential of computational methods in #biomedical #research, aligning with our mission to innovate and enhance #healthcare solutions. We encourage our community to explore this publication and join us in embracing the future of #insilico methodologies. We are very proud of our colleagues Alessandra Aldieri, Thiranja, Prasad Babarenda Gamage, Antonino Amedeo La Mattina, Axel Loewe, Prof. Francesco Pappalardo, our coordinator Prof. Marco Viceconti, and the entire #InSilicoWorld Community of Practice for their invaluable collaboration and expertise. Full open-access article available here https://lnkd.in/da85EAgc

The In Silico World project has officially come to an end. A heartfelt thank you to everyone who has contributed over the past four years. Your exceptional dedication, talent, and collaboration have been truly remarkable. Together, this team has achieved milestones that have surpassed even the highest expectations. Your effort, commitment, and teamwork have made In Silico World an outstanding project and a genuine success. It has been a privilege to witness such excellence in action. To our coordinator Prof. Marco Viceconti from Alma Mater Studiorum – Università di Bologna, and all the colleagues, partners, and supporters who joined us on this journey - #thankyou you all for your invaluable contributions and for being such extraordinary colleagues throughout this journey called In Silico World. In Silico World is over; long live In Silico World Francesco Pappalardo from Università di Catania, Liesbet Geris from VPH Institute, Alfons Hoekstra from University of Amsterdam, Frans van de Vosse from Eindhoven University of Technology, Marian Bubak from Sano Centre for Computational Medicine, Jos Vander Sloten from KU Leuven, Vincenzo Carbone, PhD, from InSilicoTrials and Elisabetta Biasin from KU Leuven Here's the final #newsletter with all our main achievements. https://lnkd.in/dSbgi8CD

Innovation isn’t just about technology - it’s about people. Listening to society’s hopes, addressing its concerns, and building trust are the keys to driving meaningful progress. The In Silico Medicine #Infokit is a free resource designed to empower #researchers and innovators with everything they need for effective stakeholder engagement. From practical tools to clear guidelines, this Infokit produced by our colleagues from VPH Institute is here to support every stage of your journey in #insilicomedicine. Dive into the Infokit and discover how collaboration can elevate your research! 👉 https://bit.ly/49PJZW2

🎥 Excited to share the final video for the #InSilicoWorld project! “Fighting Osteoporosis with BoneStrength” showcases a groundbreaking #insilico solution tackling a critical challenge in our ageing society: #osteoporosis. By creating #DigitalTwins of femurs from simple CT scans, #BoneStrength delivers higher accuracy in fracture risk prediction, enabling earlier clinical intervention and driving the development of better therapies. We’re proud to celebrate this milestone and the innovative strides made to advance #healthcare. Watch the video and see how we’re shaping a healthier future!

As the field of #InSilicoTrials continues to grow, so does the need for tailored #education to bridge knowledge gaps across diverse stakeholder groups. Here’s how #InSilicoWorld is contributing to this mission: ➡️ Mini Courses for Stakeholders - Tailored Content: customized modules for technical and non-technical audiences, whether in training or retraining - Interactive Learning: incorporating hands-on exercises and self-assessment tools to enhance engagement and understanding ➡️ Filling Curriculum Gaps - Identify missing courses and create detailed syllabi with guidelines for lectures and practical sessions - Designed to accommodate instructor flexibility while ensuring consistency across institutions ➡️ Looking Ahead - Recommendations for integrating mini-courses into academic programs. Emphasis on ongoing collaboration to refine and sustain the educational material. We aim to equip professionals with the expertise to advance #InSilicoMedicine and its applications. Together, we are building the foundation for a skilled and innovative workforce! Thanks to Lise Gheysen and Prof. Jos Vander Sloten from partner KU Leuven for their great work! Access the document on Zenodo👇 https://lnkd.in/ePi7H2K3

🚀 Exciting update from the In Silico World project! We’re breaking down barriers to bring #InSilicoTrials closer to #healthcare. Our new education packages and lecture materials for healthcare professionals (HCPs) provide accessible insights and accredited learning resources for all skill levels.📚 From glossaries and case studies to online modules, these resources empower HCPs as champions of #InSilicoMedicine. It’s a step forward in fostering adoption and collaboration in healthcare. Ready to dive in?💡 👇 https://lnkd.in/dTAX-kGK

The In Silico World Project’s SWOT Analysis is available!🚀 Our latest "In Silico Trials: an updated #SWOT Analysis" presents a comprehensive look at the strengths, weaknesses, opportunities, and threats for #InSilicoTrials in #healthcare, providing a roadmap to help biomedical companies navigate and adopt these innovative methodologies. Explore how these #insilico trials can lower development costs, accelerate time to market, and improve ethical standards in medical product development. The analysis is a valuable resource for #industry executives looking to leverage the full potential of computational modeling and simulation. We believe in silico trials are the future, but only the biomedical industry can decide if this is indeed the case. A huge thank you to all the colleagues whose efforts and insights contributed to the creation of this document. ⬇️⬇️⬇️ https://lnkd.in/dXJDWqdz #InSilicoWorld #HealthcareInnovation #DigitalHealth #SWOTAnalysis #MedicalTechnology #BiomedicalIndustry #Biomedic #insilicoSWOT

Accelerating #Innovation in #Healthcare with Computational Models! The #InSilicoWorld Project Solution Dossier - a comprehensive record of groundbreaking solutions designed to advance healthcare through computational models and simulations - is now freely available to our community! Our mission is clear: accelerating the integration of modeling and simulation technologies in developing and assessing medicines and medical devices. Tackling seven key barriers - development, validation, accreditation, optimization, exploitation, information, and training - we’ve worked 4 years to make these advanced technologies more accessible for transformative impact. This #dossier captures some of the incredible achievements of the #ISW team, highlighting advancements in accuracy, efficiency, and safety for a range of medical products. #HealthcareInnovation #ComputationalModeling #InSilicoWorld #InSilicoMedicine #InSilicoTrials https://lnkd.in/dtanvfR9

Our VPH Institute colleagues interviewed Elisabetta Biasin from partner KU Leuven on the importance of #DataPrivacy. In the #InSilicoWorld project, Elisabetta produced significant contributions such as the “Implementation guidance and guidelines” and “In-depth Analysis of Legal and Ethical Requirements”, which are part of the ISW “Ethical and Legal Framework" that offers guidelines on the ethical and legal aspects of #InSilicoTrials for researchers and end users. Now, go more in-depth with the 5th Episode of the "Digital Twin Theory" Podcast👇