January 24/31, 2023, Vol 329, No. 4, Pages 273-350

This Week in JAMA

Audio Highlights

Abstract Full Text

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JAMA. 2023;329(4):e2215773. doi:10.1001/jama.2022.15773

Audio: Fluvoxamine for Outpatients With Mild to Moderate COVID-19, Accuracy of Stroke Risk Prediction Models, Organization and Performance of US Health Systems, and more

Original Investigation

Effect of Fluvoxamine vs Placebo on Time to Sustained Recovery in Outpatients With Mild to Moderate COVID-19: A Randomized Clinical Trial

Matthew W. McCarthy, MD; Susanna Naggie, MD, MHS; David R. Boulware, MD, MPH; et al.

Abstract Full Text

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JAMA. 2023;329(4):296-305. doi:10.1001/jama.2022.24100

This randomized, placebo-controlled platform trial compares the use of low-dose fluvoxamine (50 mg twice daily) for 10 days compared with placebo in outpatients with mild to moderate COVID-19.

Podcast: Fluvoxamine vs Placebo and Time to Sustained Recovery From Mild or Moderate COVID-19

Editorial
Lack of Benefit of Fluvoxamine for COVID-19
Adarsh Bhimraj, MD; Jason C. Gallagher, PharmD

JAMA

Predictive Accuracy of Stroke Risk Prediction Models Across Black and White Race, Sex, and Age Groups

Chuan Hong, PhD; Michael J. Pencina, PhD; Daniel M. Wojdyla, MS; et al.

Abstract Full Text

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JAMA. 2023;329(4):306-317. doi:10.1001/jama.2022.24683

This retrospective cohort study compares stroke-specific algorithms with pooled cohort equations developed for atherosclerotic cardiovascular disease for the prediction of new-onset stroke across different subgroups (race, sex, and age) and the added value of novel machine learning techniques.

Estimated Prevalence and Clinical Manifestations of UBA1 Variants Associated With VEXAS Syndrome in a Clinical Population

David B. Beck, MD, PhD; Dale L. Bodian, PhD; Vandan Shah, MD; et al.

Abstract Full Text

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JAMA. 2023;329(4):318-324. doi:10.1001/jama.2022.24836

This retrospective observational study evaluates UBA1 variants in exome data from individuals in the Geisinger MyCode Community Health Initiative.

Research Letter

Trends in Sexual Assault Against Detainees in US Immigration Detention Centers, 2018-2022

Nicole Lue, BA; Joseph Nwadiuko, MD, MPH, MSHP; Parveen Parmar, MD, MPH; et al.

Abstract Full Text

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JAMA. 2023;329(4):338-339. doi:10.1001/jama.2022.22938

This study examines sexual assault allegations perpetrated against individuals detained across US Immigration and Customs Enforcement (ICE) detention facilities from 2018 to 2022.

Association Between Billing Patient Portal Messages as e-Visits and Patient Messaging Volume

A. Jay Holmgren, PhD, MHI; Maria E. Byron, MD; Carrie K. Grouse, MD; et al.

Abstract Full Text

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JAMA. 2023;329(4):339-342. doi:10.1001/jama.2022.24710

This study evaluates the adoption of clinician billing for patient portal messages as e-visits, prompted by significant increases in patient messaging after the onset of the COVID-19 pandemic.

Special Communication

Organization and Performance of US Health Systems

Nancy D. Beaulieu, PhD; Michael E. Chernew, PhD; J. Michael McWilliams, MD, PhD; et al.

Abstract Full Text

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JAMA. 2023;329(4):325-335. doi:10.1001/jama.2022.24032

This Special Communication examines health systems in the United States, assesses differences between physicians and hospitals in and outside of health systems, and compares quality and cost of care delivered by physicians and hospitals in and outside of health systems.

Editorial
Health Systems—The Present and the Future
Lawrence P. Casalino, MD, PhD

JAMA

Viewpoint

Prevention of Bias and Discrimination in Clinical Practice Algorithms

Carmel Shachar, JD, MPH; Sara Gerke, Dipl-Jur Univ, MA

Abstract Full Text

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JAMA. 2023;329(4):283-284. doi:10.1001/jama.2022.23867

This Viewpoint discusses a proposed DHHS rule to address discrimination in clinical algorithms and the need for additional considerations to ensure the burden of liability for biased algorithms is not disproportionately placed on health care professionals.

Clinical Algorithms, Antidiscrimination Laws, and Medical Device Regulation

Katherine E. Goodman, PhD, JD; Daniel J. Morgan, MD, MS; Diane E. Hoffmann, JD, MSc

Abstract Full Text

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JAMA. 2023;329(4):285-286. doi:10.1001/jama.2022.23870

This Viewpoint discusses recent legal directives by the DHHS and FDA that could increase health care entities’ liability for possible discriminatory biases of clinical algorithms and the need for additional legal clarity to avoid adverse effects on algorithm development and use.

Disentangling the Role of Health Care Systems in Producing High-Quality Care

Valerie A. Lewis, PhD; Genevra F. Murray, PhD; Darren A. DeWalt, MD, MPH

Abstract Full Text

JAMA. 2023;329(4):287-288. doi:10.1001/jama.2022.24728

This Viewpoint examines in-depth 5 features of health care systems that may influence quality of care: pooled resources, centralization, standardization, interprovider coordination, and cross-practice learning.

A Piece of My Mind

Next Year

Eleanor R. Menzin, MD

Abstract Full Text

JAMA. 2023;329(4):289-290. doi:10.1001/jama.2022.24056

In this narrative medicine essay, a pediatrician whose youngest child will start college next fall contemplates how she will shift focus on her career without competing interests.

Editorial

Lack of Benefit of Fluvoxamine for COVID-19

Adarsh Bhimraj, MD; Jason C. Gallagher, PharmD

Abstract Full Text

free access

JAMA. 2023;329(4):291-292. doi:10.1001/jama.2022.23954

Health Systems—The Present and the Future

Lawrence P. Casalino, MD, PhD

Abstract Full Text

JAMA. 2023;329(4):293-294. doi:10.1001/jama.2022.24141

JAMA Guide to Statistics and Methods

Sequential, Multiple Assignment, Randomized Trial Designs

Kelley M. Kidwell, PhD; Daniel Almirall, PhD

Abstract Full Text

has active quiz has audio

JAMA. 2023;329(4):336-337. doi:10.1001/jama.2022.24324

This JAMA Guide to Statistics and Methods explains sequential, multiple assignment, randomized trial (SMART) study designs, in which some or all participants are randomized at 2 or more decision points depending on the participant’s response to prior treatment.

Audio: Sequential, Multiple Assignment, Randomized Trial Designs With Dr Kidwell

Editor's Note

Poetry and Medicine and New Poetry Commentaries in JAMA

Rafael Campo, MA, MD

Abstract Full Text

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JAMA. 2023;329(4):295. doi:10.1001/jama.2022.25105

Editor's Note
Vagal Maneuvers
Rafael Campo, MA, MD

JAMA

Vagal Maneuvers

Rafael Campo, MA, MD

Abstract Full Text

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JAMA. 2023;329(4):345. doi:10.1001/jama.2022.24456

Editor's Note
Poetry and Medicine and New Poetry Commentaries in JAMA
Rafael Campo, MA, MD

JAMA

Medical News & Perspectives

Quick Uptakes

Study: Short Spurts of Vigorous Physical Activity During Daily Life Are Associated With Lower Mortality

Melissa Suran, PhD, MSJ

Abstract Full Text

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JAMA. 2023;329(4):275-276. doi:10.1001/jama.2022.24054

This Medical News article discusses a recent study that investigated the benefits of brief bursts of intense physical activity during daily life.

Audio: January 2023 Medical News Summary

News From the Centers for Disease Control and Prevention

US Life Expectancy in 2021 Lowest Since 1996

Bridget M. Kuehn, MSJ

Abstract Full Text

JAMA. 2023;329(4):280. doi:10.1001/jama.2022.23562

Fentanyl Drives Startling Increases in Adolescent Overdose Deaths

Bridget M. Kuehn, MSJ

Abstract Full Text

JAMA. 2023;329(4):280-281. doi:10.1001/jama.2022.23563

Clinical Trials Update

Low-Carbohydrate, High-Fat Diet Improved Type 2 Diabetes Without Restricting Calories

Anita Slomski

Abstract Full Text

JAMA. 2023;329(4):278. doi:10.1001/jama.2022.23559

More Durable Pelvic Floor Muscle Training With Digital Device

Anita Slomski

Abstract Full Text

JAMA. 2023;329(4):278. doi:10.1001/jama.2022.23560

Ebola Vaccines Safe and Immunogenic in 2 Trials

Anita Slomski

Abstract Full Text

JAMA. 2023;329(4):278-279. doi:10.1001/jama.2022.23561

Novel Oral Polio Vaccine Safely Induces Antibodies Among Vaccine-Naive Infants

Anita Slomski

Abstract Full Text

JAMA. 2023;329(4):279. doi:10.1001/jama.2022.25137

Health Agencies Update

Government Accountability Office Examines Political Interference Among US Health Agencies

Melissa Suran, PhD, MSJ

Abstract Full Text

JAMA. 2023;329(4):277. doi:10.1001/jama.2022.23556

Updated Demographics and Health Stats for Older Adults Released

Melissa Suran, PhD, MSJ

Abstract Full Text

JAMA. 2023;329(4):277. doi:10.1001/jama.2022.23557

CMS Recommends Standardizing “Health Care Attachments”

Melissa Suran, PhD, MSJ

Abstract Full Text

JAMA. 2023;329(4):277. doi:10.1001/jama.2022.23558

Poetry and Medicine

Viva Las Vagus

Nancy Naomi Carlson, PhD

Abstract Full Text

JAMA. 2023;329(4):345. doi:10.1001/jama.2022.23802

Editor's Note
Vagal Maneuvers
Rafael Campo, MA, MD

JAMA

JAMA Revisited

Efficiency in Medicine

Abstract Full Text

JAMA. 2023;329(4):346. doi:10.1001/jama.2022.15774

JAMA Patient Page

Rabies

Jill Jin, MD, MPH

Abstract Full Text

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JAMA. 2023;329(4):350. doi:10.1001/jama.2022.22254

This JAMA Patient Page describes rabies and its symptoms, diagnosis, and prevention measures.

Comment & Response

Racial Differences in Detection of Fever Using Temporal vs Oral Temperature Measurements

David M. Newman, MD

Abstract Full Text

JAMA. 2023;329(4):342. doi:10.1001/jama.2022.21349

Racial Differences in Detection of Fever Using Temporal vs Oral Temperature Measurements

Francesco Pompei, PhD; Marybeth Pompei, DPS, RN

Abstract Full Text

JAMA. 2023;329(4):342. doi:10.1001/jama.2022.21352

Racial Differences in Detection of Fever Using Temporal vs Oral Temperature Measurements—Reply

Sivasubramanium V. Bhavani, MD, MS; Zanthia Wiley, MD; Ighovwerha Ofotokun, MD, MSc

Abstract Full Text

JAMA. 2023;329(4):342-343. doi:10.1001/jama.2022.21356

Improvements in Adverse Event Rates Among Hospitalized Patients

Noel Eldridge, MS

Abstract Full Text

JAMA. 2023;329(4):343. doi:10.1001/jama.2022.21465

Editorial
Improvements in Hospital Adverse Event Rates: Achieving Statistically Significant and Clinically Meaningful Results
William V. Padula, PhD; Peter J. Pronovost, MD, PhD

JAMA
- Podcast: Progress in Adverse Event Rates in US Hospitalized Patients

Improvements in Adverse Event Rates Among Hospitalized Patients—Reply

William V. Padula, PhD; Peter J. Pronovost, MD, PhD

Abstract Full Text

JAMA. 2023;329(4):344. doi:10.1001/jama.2022.21468

Editorial
Improvements in Hospital Adverse Event Rates: Achieving Statistically Significant and Clinically Meaningful Results
William V. Padula, PhD; Peter J. Pronovost, MD, PhD

JAMA
- Podcast: Progress in Adverse Event Rates in US Hospitalized Patients

Correction

Incorrect Affiliations

Abstract Full Text

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JAMA. 2023;329(4):344. doi:10.1001/jama.2022.24467

October 2024 - July 1883

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January 24/31, 2023, Vol 329, No. 4, Pages 273-350

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