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February 7, 2023, Vol 329, No. 5, Pages 357-434

This Week in JAMA

Audio Highlights

Abstract Full Text
free access online only has audio
JAMA. 2023;329(5):e2215782. doi:10.1001/jama.2022.15782
  • Audio: Aflibercept to Prevent Vision Complications of Diabetic Retinopathy, History of Adverse Pregnancy Outcomes and CT-Identified Coronary Artery Disease, Review of Managing Menopausal Symptoms, and more
Original Investigation

Four-Year Visual Outcomes in the Protocol W Randomized Trial of Intravitreous Aflibercept for Prevention of Vision-Threatening Complications of Diabetic Retinopathy

Raj K. Maturi, MD; Adam R. Glassman, MS; Kristin Josic, PHD; et al.
Abstract Full Text
free access
JAMA. 2023;329(5):376-385. doi:10.1001/jama.2022.25029

This randomized clinical trial analyzes the effects of aflibercept injections vs sham for reducing disease progression and improving long-term visual acuity in patients with nonproliferative diabetic retinopathy.

Association Between Drug Characteristics and Manufacturer Spending on Direct-to-Consumer Advertising

Michael J. DiStefano, PhD; Jenny M. Markell, BA; Caroline C. Doherty, MHS; et al.
Abstract Full Text
free access
JAMA. 2023;329(5):386-392. doi:10.1001/jama.2022.23968

This pharmacoeconomic study estimates associations between drug characteristics and the proportion of manufacturer promotional spending allocated to direct-to-consumer advertising.

Association Between History of Adverse Pregnancy Outcomes and Coronary Artery Disease Assessed by Coronary Computed Tomography Angiography

Sofia Sederholm Lawesson, MD, PhD; Eva Swahn, MD, PhD; Mats Pihlsgård, PhD; et al.
Abstract Full Text
free access
JAMA. 2023;329(5):393-404. doi:10.1001/jama.2022.24093

This study assesses the association of history of adverse pregnancy outcomes with subsequent image-identified coronary artery disease among a population-based cohort of women in Sweden.

Research Letter

Accuracy of Electronic Health Record Food Insecurity, Housing Instability, and Financial Strain Screening in Adult Primary Care

Christopher A. Harle, PhD; Wei Wu, PhD; Joshua R. Vest, PhD, MPH
Abstract Full Text
free access
JAMA. 2023;329(5):423-424. doi:10.1001/jama.2022.23631

This study assesses the accuracy of electronic health record–based screening questionnaires about social risk factors using external single-domain questionnaires as a comparator.

Viewpoint

Pulse Oximeters and Violation of Federal Antidiscrimination Law

Annabel Kupke, BA, BS; Carmel Shachar, JD, MPH; Christopher Robertson, JD, PhD, MA
Abstract Full Text
JAMA. 2023;329(5):365-366. doi:10.1001/jama.2022.24976

This Viewpoint discusses how some pulse oximeters can provide incorrect oxygen saturation data for dark-skinned patients compared with light-skinned patients, describes the reasons that biased oximeters remained in use, and highlights why a rule recently proposed by the US Department of Health and Human Services may bring about needed change in the use of pulse oximetry for patients with dark skin.

Pharmacy Benefit Managers and the Federal Trade Commission: A Relationship Gone Sour

Barak D. Richman, JD, PhD; Eli Y. Adashi, MD, MS
Abstract Full Text
JAMA. 2023;329(5):367-368. doi:10.1001/jama.2022.24731

This Viewpoint provides a brief history of pharmacy benefit managers (PBMs), describes the ways in which PBMs have acquired influence in the prescription drug distribution system, and suggests possible scenarios surrounding the June 2022 decision by the Federal Trade Commission to launch an investigation into PBM business practices.

A Piece of My Mind

Gray Hair

Dean A. Seehusen, MD, MPH
Abstract Full Text
JAMA. 2023;329(5):369-370. doi:10.1001/jama.2022.24577

In this narrative medicine essay, a chair of a family medicine department views the wide generation gap between him and his medical students as an unexpected turn from what he had imagined he would feel upon becoming a senior physician.

Editorial

Manufacturer Spending on Direct-to-Consumer Advertising for Pharmaceutical Products

Amanda Starc, PhD
Abstract Full Text
JAMA. 2023;329(5):371-373. doi:10.1001/jama.2022.24078

Adverse Pregnancy Outcomes—Risk Enhancers Whose Time Has Finally Arrived

Natalie A. Bello, MD, MPH
Abstract Full Text
JAMA. 2023;329(5):373-375. doi:10.1001/jama.2022.24387
Review

Management of Menopausal Symptoms: A Review

Carolyn J. Crandall, MD, MS; Jaya M. Mehta, MD; JoAnn E. Manson, MD, DrPH
Abstract Full Text
has active quiz has audio
JAMA. 2023;329(5):405-420. doi:10.1001/jama.2022.24140

This narrative review discusses treatments for women with bothersome vasomotor symptoms (hot flashes, night sweats, or both) and genitourinary syndrome of menopause (genitourinary symptoms), which include hormonal and nonhormonal options.

  • Audio: Treatment of Menopausal Symptoms
JAMA Insights

Management of Latent Tuberculosis Infection

Steven Kim, MD; Rebecca Thal, MSN, NP; Daria Szkwarko, DO, MPH
Abstract Full Text
free access has active quiz
JAMA. 2023;329(5):421-422. doi:10.1001/jama.2022.24362

This JAMA Insights Clinical Update examines treatment recommendations and therapy options among adults with latent tuberculosis infection.

Editor's Note

More Medical News Clinicians Can Use

Jennifer Abbasi; Preeti N. Malani, MD, MSJ
Abstract Full Text
free access
JAMA. 2023;329(5):359. doi:10.1001/jama.2023.0409
Medical News & Perspectives

Quick Uptakes

Swab the Throat as Well as the Nose? The Debate Over the Best Way to Test for SARS-CoV-2

Rita Rubin, MA
Abstract Full Text
free access has audio
JAMA. 2023;329(5):357-358. doi:10.1001/jama.2022.23311

This Medical News article discusses whether swabbing both the nose and the throat might improve the sensitivity of rapid antigen COVID-19 tests.

  • Audio: January 2023 Medical News Summary
News From the JAMA Network

From Thought to Text: How an Endovascular Brain-Computer Interface Could Help Patients With Severe Paralysis Communicate

Jennifer Abbasi; Melissa Suran, PhD, MSJ
Abstract Full Text
has audio
JAMA. 2023;329(5):360-362. doi:10.1001/jama.2022.24343

This Medical News article discusses a recent clinical trial of a brain-computer interface implanted through the vascular system.

  • Audio: January 2023 Medical News Summary
Medical News in Brief

Lecanemab Gains FDA Approval for Early Alzheimer Disease

Howard D. Larkin
Abstract Full Text
JAMA. 2023;329(5):363. doi:10.1001/jama.2022.24490

Substance Use, Mental Health Challenges Widespread in 2021

Howard D. Larkin
Abstract Full Text
JAMA. 2023;329(5):363. doi:10.1001/jama.2022.24491

Gene Edited Tumor Cells Kill and Prevent Cancer in Mice

Howard D. Larkin
Abstract Full Text
JAMA. 2023;329(5):363. doi:10.1001/jama.2022.24492

Child Asthma Tied to Specific Urban Air Pollutants

Howard D. Larkin
Abstract Full Text
JAMA. 2023;329(5):363. doi:10.1001/jama.2022.24493

NIH Pilots Telehealth Program for COVID-19

Howard D. Larkin
Abstract Full Text
free access
JAMA. 2023;329(5):363-364. doi:10.1001/jama.2022.24494

AAP Recommends Immediate, Intensive Treatment for Child Obesity

Howard D. Larkin
Abstract Full Text
JAMA. 2023;329(5):364. doi:10.1001/jama.2022.24495

Sickle Cell Disease Gene Therapy Trial Paused

Howard D. Larkin
Abstract Full Text
JAMA. 2023;329(5):364. doi:10.1001/jama.2022.24496

Letters to Clinicians May Promote Better-Informed Opioid Prescribing

Howard D. Larkin
Abstract Full Text
JAMA. 2023;329(5):364. doi:10.1001/jama.2022.24497

Patients With Mild COVID-19 at Risk of Some Post–COVID-19 Condition Symptoms

Howard D. Larkin
Abstract Full Text
free access
JAMA. 2023;329(5):364. doi:10.1001/jama.2022.24498
Poetry and Medicine

Visitation

Elane Kim
Abstract Full Text
JAMA. 2023;329(5):429. doi:10.1001/jama.2022.22988
JAMA Revisited

Congressional Testimony: The Importance of the Right Witness

Abstract Full Text
JAMA. 2023;329(5):430. doi:10.1001/jama.2022.15783
JAMA Patient Page

What Is an Ectopic Pregnancy?

Iris T. Lee, MD; Kurt T. Barnhart, MD, MSCE
Abstract Full Text
free access
JAMA. 2023;329(5):434. doi:10.1001/jama.2022.22941

This JAMA Patient Page describes ectopic pregnancy and its risk factors, symptoms, diagnosis, and treatment.

Comment & Response

SARS-CoV-2 Results in Self-collected Nasal Swabs vs Swabs Collected by Health Care Workers in Children and Adolescents

Ki Ho Hong, MD, PhD; Heungsup Sung, MD, PhD
Abstract Full Text
JAMA. 2023;329(5):424-425. doi:10.1001/jama.2022.21596

SARS-CoV-2 Results in Self-collected Nasal Swabs vs Swabs Collected by Health Care Workers in Children and Adolescents—Reply

Jesse J. Waggoner, MD; Erika A. Tyburski, BS; Wilbur A. Lam, MD, PhD
Abstract Full Text
JAMA. 2023;329(5):425-426. doi:10.1001/jama.2022.21599

Vaccination, Acute Myocardial Infarction, and Ischemic Stroke After COVID-19 Infection

Wei-Min Chu, MD, PhD; Chi-Yen Wang, MD; James Cheng-Chung Wei, MD, PhD
Abstract Full Text
JAMA. 2023;329(5):426. doi:10.1001/jama.2022.21624

Vaccination, Acute Myocardial Infarction, and Ischemic Stroke After COVID-19 Infection—Reply

Kyungmin Huh, MD; Young-Eun Kim, PhD; Jaehun Jung, MD, PhD
Abstract Full Text
JAMA. 2023;329(5):426-427. doi:10.1001/jama.2022.21627

Mpox Outbreak Update

Ya Bin Zhou, MD, PhD
Abstract Full Text
JAMA. 2023;329(5):427-428. doi:10.1001/jama.2022.21630

Mpox Outbreak Update—Reply

Carlos del Rio, MD; Preeti Malani, MD, MSJ
Abstract Full Text
JAMA. 2023;329(5):428. doi:10.1001/jama.2022.21633
JAMA Masthead

JAMA

Abstract Full Text
free access
JAMA. 2023;329(5):365-366. doi:10.1001/jama.2022.15781

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