This 32-country randomized clinical trial assesses the effects of bempedoic acid on cardiovascular outcomes in statin-intolerant patients receiving bempedoic acid vs placebo for primary prevention of a first major adverse cardiovascular event.
This randomized clinical trial compares the effect of continuous administration of meropenem vs intermittent administration on a composite outcome of mortality and emergence of pandrug-resistant or extensively drug-resistant bacteria in critically ill patients with sepsis.
This randomized trial compares the efficacy and tolerability of 2 durations of cytisinicline treatment (6 or 12 weeks) vs placebo for smoking cessation in adults who smoked cigarettes daily.
This prospective multicenter study of 400 hospitalized infants with a suspected genetic disorder evaluated rates of molecular diagnostic yield, time to return of results, and clinical utility by comparing between genomic sequencing and targeted neonatal gene-sequencing testing.
This study investigates the association between bivalent COVID-19 vaccines and ischemic stroke, as well as the effect of simultaneous influenza vaccination on the association.
This study examines whether Medicare Advantage (MA) enrollees with more chronic conditions were more likely to disenroll when MA enrollment grew rapidly from 2009 to 2019.
This Viewpoint discusses the Medicare Physician Fee Schedule and its flaws, including how they might be remedied by severing CMS dependence on Relative Value Update Committee estimates of time and intensity.
This Viewpoint examines Medicare physician payment flaws and needed reforms, including changes implemented by Congress, CMS, commercial payers, and physician employers.
This Viewpoint discusses the ramifications of the Dobbs v Jackson Women’s Health Organization decision by the US Supreme Court and the state of reproductive health care in the US.
In this narrative medicine essay, a resident otolaryngologist’s grief over the loss of his daughter at nearly 20 weeks’ gestation nearly crushes him until he finds relief hearing the stories of other parents at a hospital-sponsored rememberance celebration.
This review summarizes current evidence regarding diagnosis and treatment of Cushing syndrome due to endogenous overproduction of cortisol.
This JAMA Insights Clinical Update discusses current recommendations regarding prevention of Pneumocystis pneumonia in patients who are immunocompromised.
This Medical News article discusses new research presented at the American Society of Clinical Oncology’s 2023 annual meeting.
This Medical News feature discusses the flight of clinics from states with abortion bans to those without them.
This JAMA Patient Page describes aortic dissection, a tear in the aorta, and how it is diagnosed and treated.