Adrenalectomy is the surgical removal of one or both adrenal glands. You might need this procedure if your adrenal glands make too many hormones or if you have cancer in your adrenal gland. In most cases, surgeons can do laparoscopic adrenalectomy, which requires fewer incisions (cuts) and sutures for a quicker recovery.
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Adrenalectomy is surgery to remove one or both adrenal glands — small glands above each kidney. Your adrenal glands are part of your endocrine system. They affect growth, development, metabolism and sexual function.
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Cleveland Clinic is a non-profit academic medical center. Advertising on our site helps support our mission. We do not endorse non-Cleveland Clinic products or services. Policy
You might need an adrenalectomy if you have adrenal cancer in one or both glands or if your glands produce too much of a certain hormone. Adrenal disorders that can cause an overproduction of hormones include hyperaldosteronism, pheochromocytoma and Cushing syndrome.
In many cases, surgeons can do laparoscopic adrenalectomy (which requires one to four small incisions) instead of open surgery (which requires a large incision across your belly). Depending on your specific situation, a surgeon may remove one adrenal gland (unilateral adrenalectomy) or both adrenal glands (bilateral adrenalectomy). They can also remove certain types of adrenal tumors without removing your entire adrenal gland (partial adrenalectomy).
You’ll need to make specific preparations leading up to the day of your surgery. You may need additional imaging tests. Or you might need to take medication or follow specific dietary guidelines. Your provider will talk with you before your appointment so you know what to expect.
Because you’ll receive general anesthesia for your procedure, you should arrange for a friend or family member to drive you to and from your surgery.
During an adrenalectomy, a surgeon removes part or all of your adrenal gland(s). They can do this in one of three ways:
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During a consultation with your healthcare provider, they’ll review these options with you and determine which one is best for your situation.
On average, an adrenalectomy takes about two to three hours to complete.
If you had a laparoscopic or robotic adrenalectomy, you’ll probably go home the same day as your procedure. If you had open surgery, you might need to stay in the hospital for up to five days. Your provider will help you resume normal routines like eating and drinking. They’ll also help you walk around as soon as possible, to prevent blood clots and other complications.
Your healthcare team will prescribe any necessary medications, schedule a follow-up visit and give you instructions to help you have a successful recovery. In general, you’ll want to:
As with any surgical procedure, complications may occur. They’re more likely with an open adrenalectomy than with laparoscopic or robotic adrenalectomy.
Possible complications include:
In general, adrenalectomy recovery takes one to two weeks. It could be longer if you had open surgery. It’s normal to develop some pain around your incision sites. You can manage this side effect with NSAIDs (nonsteroidal anti-inflammatory drugs) like ibuprofen (Advil®) or naproxen sodium (Aleve®).
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Everyone gets better at a different pace, but most people recover without complications in two to three weeks. The symptoms you had before your adrenalectomy should go away almost immediately. If your provider removed a cancerous tumor, they’ll monitor you for cancer recurrence (return).
Most people can return to work or school within one to two weeks. Be sure to ask your healthcare provider when it’s safe for you to resume routine activities.
Call your healthcare provider if you:
Call 911 or head to your nearest emergency room if you:
Yes, your body only needs one healthy adrenal gland to function. If you have both adrenal glands removed, or if your remaining adrenal gland doesn’t work, medications can replace essential hormones. With appropriate management and treatment, people without adrenal glands have a normal life expectancy.
No one likes hearing that they need surgery. But if you have adrenal gland cancer or certain adrenal disorders — like hyperaldosteronism or Cushing disease — adrenalectomy can stop your symptoms and get you on the road to recovery. If your healthcare provider recommends adrenalectomy, ask them what to expect, including whether you’ll need medication to replace hormone production.
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Last reviewed on 03/22/2024.
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