iPSpine

Very happy and proud to announce the release of our new iPSpine paper https://lnkd.in/ewuPxuHw In collaboration with LUMC and Nantes University we generated two human ACAN reporter iPSC lines. We demonstrate their functionality for notochordal and chondrogenic lineage commitments. This reporter can be used for regenerative medicine applications beyond the IVD and cartilage to tissues where ACAN is abundant in the ECM, including brain and heart. Thank you!: Xiaole Tong; Deepani Poramba Liyanage; Marcella van Hoolwerff; Frank Riemers; Joaquin Montilla Rojo; Daniela Salvatori; Anne CAMUS; Julie WARIN; Niels Geijsen; Yolande F. M. Ramos; Ingrid Meulenbelt; Marianna Tryfonidou; Peng Shang

📢 Our #iPSpine end of project newsletter is ready!   🔎 Come and have a look as we dive deep into the #iPSpine project. Learn about when our project first started, gain insights from project coordinator Marianna Tryfonidou, get links to our latest publications, and more! 🖊 This newsletter features a spotlight section on iPSpine’s patient involvement. Read about when our patient advisory board formed, what its goals throughout the project were, and where you can learn more.   Don’t miss out, read it here: https://lnkd.in/e2yg2cTB   Utrecht University Eindhoven University of Technology Nantes Université UMC Utrecht University of Galway Ulm University University of Bern INSERM @NMI Research Institute AO Research Institute Davos (ARI) Sheffield Hallam University Università Campus Bio-Medico di Roma NTrans Technologies BV University of Montpellier SpineServ University of Miami The University of Hong Kong Phlexglobal - a PharmaLex company now part of Cencora ReumaNederland Catalyze Group Leiden University Medical Center The University of Sheffield #Newsletter #stemcells #lowerbackpain

Today Lisanne Laagland presented the collaborative work of multiple iPSpine partners at the Veterinary Science Day held at Utrecht University for which she won the Award for Best Poster! Congrats Lisanne👏🏼

Mariska S. represented ReumaNederland during the 3-day iPSpine meeting bringing in the patient-context to our scientific discussions. We celebrated our achievements and shared the renewed infographics summarizing 5,5 years of work in less than 90 seconds!

So happy to see the iPSpine Spine tester To Go make a difference in reducing animal experiments and finally adding Biomechanics to read outs of large animal studies in spine research. Thank you Prof. Dr. Hans-Joachim Wilke, Jan Jansen

Mariska S. represented ReumaNederland during the 3-day iPSpine meeting bringing in the patient-context to our scientific discussions. We celebrated our achievements and shared the renewed infographics summarizing 5,5 years of work in less than 90 seconds!

To all good things comes an end, but it was amazing meeting and working with all #iPSpine team members! Luckily, all new insights open doors to keep up these great collaborations so it’s definitely not a final goodbye!👩🏼🔬🧫🤗

🎁 ...and that’s a wrap! After three successful days, our final #iPSpine consortium meeting comes to a close.     ✅ A jam-packed agenda has seen each project work package present their findings. From the development of stem cells and smart biomaterials to the ethical considerations and regulatory frameworks that make research possible, not a stone was left unturned. Complemented with fascinating topic talks diving deep into many of the journeys that it took to get to where we are now, our final consortium was a big success!    🙏 A huge thank you to our amazing iPSpine team for their brilliant work over the past 5 years! And a big thanks to Utrecht University and Catalyze Group for hosting and organizing this wonderful event in the beautiful city of Utrecht!    Stay tuned as iPSpine heads into its final weeks!    Utrecht University Eindhoven University of Technology Nantes Université Universitair Medisch Centrum Utrecht University of Galway Ulm University University of Bern INSERM @NMI Research Institute AO Research Institute Davos (ARI) Sheffield Hallam University Università Campus Bio-Medico di Roma NTrans Technologies BV University of Montpellier SpineServ University of Miami The University of Hong Kong PharmaLex ReumaNederland Catalyze Group Leiden University Medical Center The University of Sheffield 

🔦 Another insight! 👩🏫 Zaklina Buljovcic and Angela Vogt-Eisele were at #iPSpine: a unique opportunity to have worked with Phlexglobal - a PharmaLex company now part of Cencora in guiding iPSpine during our regulatory journey of our 1st of class therapy in development.

🔎 Come have a look as Rosario Isasi presents at our final #iPSpine consortium meeting: regulations and policy - The backbone of our scientific work in our battle to change the landscape and push ATMP therapies forward!