PD-value

Dear LinkedIn Community, some incredible news that we are ecstatic and full of gratitude to share with you! On October 31st, we announced that PD-value is among the FD Gazellen this year. Last Thursday, Het Financieele Dagblad announced that we ranked 12th among the SMEs in the East region and 84th among the 1003 Gazellen, the fastest-growing companies, in the Netherlands. We want to thank Het Financieele Dagblad for this special recognition and our clients and PD-value team for making this possible. We are honored and motivated more than ever to continue providing our clients with the quality services they need, our employees with the environment they can flourish in, and our community and society the values they need from our company. Growth only for growth's sake has never been a priority at our company. However, growth means contributing to more exciting client and academic projects, attracting more teammates with exceptional backgrounds and personalities, and creating more value for our scientific community and society. All while sticking to our values. And that we celebrate. Thank you for celebrating with us! #fdgazelle #fdgazelle2023 #fdgazellen #Fdgazellen2023 #growth #drugdevelopment #modelingandsimulation #pkpd #pbpk #systemsbiology #qsp #innovation

Our team had an incredible experience at the FIGON Dutch Medicine Days with an outstanding lineup of speakers in the fields of obesity, structural biology and signaling, drug repurposing, predictive models, and many more. A big thank you to the organizers and committees for putting together such a successful, informative, and engaging conference. Your hard work and dedication truly showed throughout the event. Congratulations to all the PhD Student Award winners and Poster Award winners for their outstanding contributions and achievements. Special mention to the networking sessions, including the lunches, and especially the conference dinner - the perfect way to network and unwind after a day full of insightful discussions. We are happy to be part of the Dutch Medicine community and can't wait for future opportunities to further knowledge and innovation in the industry. #FIGONDutchMedicineDays #DMD2024 #DrugDevelopment #Innovation #Networking #modelingandsimulation #pkpd #pbpk #qsp #systemsbiology Hyphen Projects

We are thrilled to mark a significant milestone - our 10-year anniversary! 🎉 Over the past decade, PD-value has grown into a trusted partner in pharmacometric and systems biology modeling, advancing drug development. To commemorate this occasion, we hosted a special symposium featuring 6 inspiring guest speakers and our CEO, Jeroen Elassaiss-Schaap, who shared valuable insights into their research and the future of our field. From academia to industry, Elizabeth (Liesbeth) De Lange, Kees Bol, Asina G., Sieto Bosgra, Roeland Merks and Kathrin Thedieck showed us the many aspects and benefits of modeling and simulation approaches. The evening was capped off with a delightful walking dinner and drinks, offering a perfect opportunity to connect, reflect, and celebrate with our colleagues and partners. A huge thank you to our speakers, clients, and the entire PD-value team for their dedication and support throughout the years. Here’s to many more years of success and collaboration! 🥂 Do you want to be part of our journey? Follow us on LinkedIn to learn more about our activities. #10YearAnniversary #Growth #Pharmacometrics #pkpd #pbpk #qsp #systemsbiology #drugdevelopment

It is almost a month before ACoP 2024, and we are thrilled to be exhibiting at the 15th edition of this great conference! Our team, Basak Tektemur-Altay, Jeroen Elassaiss-Schaap, and Luuk Huijts, will be more than happy to discuss your research and our capabilities in PK-PD, PBPK, QSP, and Systems Biology. We will also introduce our new approach to PK-PD modeling, Impress-M®, and our sister company Gedmore B.V.. Are you registered? Then, visit us at booth 26 and don’t forget to visit our virtual booth, where you can find our intro video and more. See you in Phoenix, Arizona! #ACoP2024 #pkpd #pbpk #qsp #systemsbiology #drugdevelopment #drugdiscovery

We are thrilled to share that our Director Systems Biology and Business Development, Basak Tektemur-Altay, will be attending BIO-Europe, November 4-6, Stockholm, Sweden. She will be sharing our capabilities in PK-PD, PBPK, QSP and Systems Biology modeling and simulation approaches supporting drug development in small molecules, antibodies and novel modalities. Do you want to leverage biological knowledge and data from experimental approaches for accelerated drug discovery and development? Let us or Basak know via a direct message, or better yet, schedule a meeting on the event portal of BIO-Europe. We look forward to seeing you in Stockholm. #BIO #BioEurope #BioEurope2024 #pkpd #pbpk #qsp #systemsbiology #drugdevelopment EBD Group

We are thrilled to share the latest paper of our mathematical modeler, Csaba Katai, on the neonatal Fc receptor (FcRn) regulated clearance mechanism for antibodies. The work not only contributes to the larger physiology-based pharmacokinetic models published in the literature but also provides a simple expression for clearance (and AUC) in terms of the model parameters, which has significant practical implications. The analysis highlights that for dose levels typically used in the clinic, this clearance mechanism is effectively linear, whereas for doses sufficiently high, such as those used in IVIG therapy, clearance is nonlinear. Furthermore, the conclusions that may be drawn from the simple expression for clearance have been shown to manifest in our in-house whole-body PBPK model (see poster 11153 presented at PAGE2024). We’d like to thank our collaborators and contributors, as well as the reviewers for their work in publishing this paper. Are you interested in this remarkable paper on the FcRn mechanismor the corresponding PAGE2024 poster? Let us know in the comments, and we'll send you a personal message with the link. Follow us for more updates from us, and contact us via direct message or an email to learn more about our modeling and simulation approaches. #pkpd #pbpk #qsp #systemsbiology #fcrn #drugdiscovery #drug development

Would you like to learn more about drug clearance and how in-vitro to in-vivo translation generates insights about liver metabolism in drug development? We explain ins and outs of in-vitro to in-vivo correlation to predict human drug clearance in our latest article. Read our bite-size piece and let us know about your opinion about in-vitro to in-vivo correlation in drug clearance. Follow us on LinkedIn for more updates about PD-value, contact us via a LinkedIn message or an email to discuss your translational pharmacology needs! #pkpd #pbpk #systemsbiology #qsp #drugdevelopment

We enjoyed sponsoring the DMDG Open Meeting together with our sister company, Gedmore B.V.! Both the meeting and promoting our sister company were thrilling. The conference was great, both from the scientific and networking aspects. We look forward to attending more events with our sister company, Gedmore B.V., for many years to come. As the PD-value team, we would also like to thank the organizers, the speakers, and the community for the great event, open discussions, and their feedback. Are you interested in PK-PD, QSP, and Systems Biology and need modeling and simulation support in your drug development? Follow us on LinkedIn or contact us by email or direct message. If you are also interested in PK automation, follow our sister company, Gedmore B.V., on LinkedIn and contact Gedmore team by email or direct message. We look forward to meeting you at upcoming events and exploring modeling and simulation options for your drug development. #DMDG #drugmetabolism #pkautomation #PKPD #systemsbiology #drugdevelopment

The PD-value team had another fun outing that is organized monthly, this time, including indoor climbing and solving a murder mystery. The excitement and teamwork displayed during these activities highlighted the collaborative spirit that drives us forward. We believe in embodying a healthy and active lifestyle, both for our bodies and minds. That's why we selected two fun and thrilling activities to choose from that challenged us physically or mentally. And the results did not disappoint. Both the climbers and detectives of our company had a great time. After working up an appetite, we concluded our day with a delicious spread of Chinese cuisine – Mandarin, to be precise – where we, again, had great suggestions from the members of our diverse team. We had the chance to try regional specials while reflecting on the day's activities and shared experiences. Here at PD-value, we believe that a healthy lifestyle isn't just about physical fitness, but also about exercising our brain muscles and fostering a strong sense of companionship within our team. Stay tuned for more adventures and team-building activities as we continue to prioritize well-being, growth, and a bit of fun within our organization! Better yet, let us know your favorite team activities. #TeamOuting #HealthyLifestyle #TeamBuilding #WorkHardPlayHard #CompanyCulture

We are ecstatic to share the news that our CEO, Jeroen Elassaiss-Schaap, has penned an exceptional article that was featured in the 10th edition of Immunowatch by MabDesign, the French biotech&pharma industry association. The article titled "Accelerating Antibody Development Through Quantitative Systems Pharmacology – The Pembrolizumab Story" provides practical insights into the power of modeling and simulation approaches to revolutionize drug development processes. By using the success story of Pembrolizumab as a prime example, our CEO showcases how our company's innovative services can play a pivotal role in accelerating drug development timelines and budgets. Read the full article in the latest issue of Immunowatch to learn more about how our services can help propel drug development forward. Do you have upcoming R&D transitions and decision points? Let us with a comment, a direct message or an email to explore how our services can support your processes! #DrugDevelopment #ModelingandSimulation #Innovation #PharmaIndustry #ImmunoOncology #BioTech