ZoBio

ZoBio

Biotechnologie

Leiden, ZH 1.704 volgers

The Integrated Fragment Discovery Engine

Over ons

ZoBio is a leading innovator that provides "gene to structure" research services in early stage drug discovery. The company is a privately held, self-funded and founded in 2004. We are specialized in 4 areas: 1) enabling proteins for biophysical and structural biology studies, 2) using biophysics to screen fragment libraries for selective ligands for a pharmaceutical target, 3) using both X-ray crystallography and NMR to provide 3D structural information on complexes of ligands bound to a protein and 4) using medicinal chemistry expertise to advance fragment "hits". 1) Every protein ZoBio produces is "crystallography" quality. For structurally unprecedented, challenging proteins, we offer our proprietary Protein Domain Trapping for screening millions of variants for high level expression of soluble, functional, monodisperse protein. 2) Orthogonal screening via our proprietary TINS NMR screening technology, SPR and high concentration, functional assays. Screen the highly optimized, poised ZoBio fragment library or your own. 3) Structural information from protein NMR and crystallography. The best of both worlds with more shots on goal to solve even the most difficult challenges. 4) Medicinal chemistry focused on bridging the challenging gap between fragment and hit. We bring deep understanding of chemistry and structural biology together to fully enable fragment based drug discovery.

Branche
Biotechnologie
Bedrijfsgrootte
11 - 50 medewerkers
Hoofdkantoor
Leiden, ZH
Type
Particuliere onderneming
Opgericht
2004
Specialismen
Protein production, Fragment library screening, Structural biology, Nuclear Magnetic Resonance, X-ray crystallography, MedChem for fragment elaboration en High throughput protein engineering

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Medewerkers van ZoBio

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