Protective effects of functional amino acids on apoptosis, inflammatory response, and pulmonary fibrosis in lipopolysaccharide-challenged mice

X Ma, Y Zhang, D Jiang, Y Yang, G Wu… - Journal of agricultural …, 2019 - ACS Publications
Lung injury is a complicated and lethal condition characterized by alveolar barrier
disruption, pulmonary edema, enhanced inflammation, and apoptosis in alveoli. However,
therapeutic strategies to ameliorate lung injury without exerting side effects are not
available. Functional amino acids have been shown to have anti-inflammatory and anti-
apoptotic effects under various conditions. The objective of this study was to test the
hypothesis that arginine, glutamine, or glycine supplementation ameliorated …

Protective effects of functional amino acids on apoptosis, inflammatory response, and pulmonary fibrosis in lipopolysaccharide-challenged mice.

MXS Ma XiaoShi, ZYC Zhang YunChang, JD Jiang Da… - 2019 - cabidigitallibrary.org
Lung injury is a complicated and lethal condition characterized by alveolar barrier
disruption, pulmonary edema, enhanced inflammation, and apoptosis in alveoli. However,
therapeutic strategies to ameliorate lung injury without exerting side effects are not
available. Functional amino acids have been shown to have anti-inflammatory and anti-
apoptotic effects under various conditions. The objective of this study was to test the
hypothesis that arginine, glutamine, or glycine supplementation ameliorated …
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