Spatiotemporal regulation of liquid-like condensates in epigenetic inheritance
… liquid-like condensate that we term the Z granule. In adult germ cells, Z granules assemble
into ordered tri-condensate … transgenerational epigenetic inheritance. We speculate that the …
into ordered tri-condensate … transgenerational epigenetic inheritance. We speculate that the …
[BOOK][B] Spatiotemporal Regulation of Liquid-like Condensates in Epigenetic Inheritance
BD Fields - 2018 - search.proquest.com
… epigenetic inheritance (TEI). We speculate that the temporal and spatial ordering of liquid-like
condensates … pathways underlying gene regulatory systems, such as RNA-directed TEI. …
condensates … pathways underlying gene regulatory systems, such as RNA-directed TEI. …
A framework for understanding the functions of biomolecular condensates across scales
AS Lyon, WB Peeples, MK Rosen - Nature Reviews Molecular Cell …, 2021 - nature.com
… This organization of condensates suggests an important role … involved in transgenerational
epigenetic inheritance and warrants … , which are liquid-like protein–RNA condensates akin to …
epigenetic inheritance and warrants … , which are liquid-like protein–RNA condensates akin to …
Higher-order organization of biomolecular condensates
… means by which RNA facilitates transgenerational epigenetic inheritance (TEI), Wan et …
spatial and temporal organization of liquid-like condensates may serve to guide RNAi inheritance …
spatial and temporal organization of liquid-like condensates may serve to guide RNAi inheritance …
[HTML][HTML] Phase separation and inheritance of repressive chromatin domains
N Akilli, T Cheutin, G Cavalli - Current Opinion in Genetics & Development, 2024 - Elsevier
… condensates, and it has been shown that HP1α condensates … whereas heterochromatin
proteins display liquid-like behavior and … epigenetic inheritance, other biomolecular condensates …
proteins display liquid-like behavior and … epigenetic inheritance, other biomolecular condensates …
Regulation of multi-condensates miscibility is required for limiting transgenerational epigenetic inheritance
G Wan, C Zhao, S Cai, S Yang, J Huang, Y Liang, P Lu… - 2023 - researchsquare.com
… paradoxically results in prolonged transgenerational epigenetic inheritance of RNAi for over
… Spatiotemporal regulation of liquid-like condensates in epigenetic inheritance. Nature 557, …
… Spatiotemporal regulation of liquid-like condensates in epigenetic inheritance. Nature 557, …
Harnessing biomolecular condensates in living cells
H Nakamura, R DeRose, T Inoue - The Journal of biochemistry, 2019 - academic.oup.com
… liquid-like condensate can thus be used to examine the mechanism of biomolecular condensate
… in different biological contexts including mRNA processing (77), epigenetic inheritance (…
… in different biological contexts including mRNA processing (77), epigenetic inheritance (…
Phase separation in genome organization across evolution
… to form condensates in association with DNA. (D) The nucleus as an emulsion of DNA …
modified to mark epigenetic states. Akin to the IDRs of biomolecular condensates, histone tails are …
modified to mark epigenetic states. Akin to the IDRs of biomolecular condensates, histone tails are …
Insights from biomolecular condensates into disease and drug development
LK Afeyan - 2022 - dspace.mit.edu
… these liquid-like compartments. A consideration of the role of … mechanism for spatiotemporally
organizing molecules into … , including transcription, epigenetic regulation, cell signaling, …
organizing molecules into … , including transcription, epigenetic regulation, cell signaling, …
Spatio-temporal organisation of histone variants: from nucleosomes to nuclei
T Karagyozova - 2023 - theses.hal.science
… , and I am proud to have inherited your lab giraffe. Next, thank … Here, I will consider epigenetics
as adaptations of chromatin … genes and link with chromatin condensation. Finally, H2A.Z …
as adaptations of chromatin … genes and link with chromatin condensation. Finally, H2A.Z …