Publisher Summary T7 RNA polymerase is an ideal model system in which to study
fundamental characteristics of the complex machine that is RNA polymerase. Although
structurally unrelated to the more complex multi‐subunit RNA polymerases, it appears that
the common functional requirements imposed on all DNA dependent RNA polymerases is
likely to be reflected in many common mechanistic features. Both the small size of the
protein and the small size of the promoter DNA allow studies in the single subunit enzymes …