The biochemistry of apoptosis

MO Hengartner - Nature, 2000 - nature.com
… apoptotic programme requires the coordinated … the basic components of the death machinery,
describe how they interact to regulate apoptosis in a coordinated manner, and discuss the

Apoptosis: biochemical aspects and clinical implications

FL Kiechle, X Zhang - Clinica Chimica Acta, 2002 - Elsevier
… This review will describe the intracellular biochemical pathways … the temporal sequence
of the biochemical signal transduction cascade that leads to Hoechst 33342-induced apoptosis

Apoptosis: the biochemistry and molecular biology of programmed cell death

RA Schwartzman, JA Cidlowski - Endocrine reviews, 1993 - academic.oup.com
… , and the numerous cell types and mediators with which programmed cell death is
associated. The bulk of the review discusses our current understanding of the biochemical and …

Mechanisms of apoptosis: integration of genetic, biochemical, and cellular indicators

BW Stewart - JNCI: Journal of the National Cancer Institute, 1994 - academic.oup.com
… of the cell surface, and ultimate sequestration of the cellular … considered synonymous with
apoptosis, and the two terms will … Apoptosis is relevant to a range of biological processes, …

Biochemical determinants of apoptosis and necrosis

DJ McConkey - Toxicology letters, 1998 - Elsevier
… within the context of what is currently known about the effector machinery for apoptotic cell
death, and possible mechanistic explanations for the switch between apoptosis and necrosis …

Morphologic and biochemical hallmarks of apoptosis

A Saraste, K Pulkki - Cardiovascular research, 2000 - academic.oup.com
… implications in the detection of apoptosis and the differentiation between apoptosis and
other … The biochemical hallmark of apoptosis is degradation of DNA by endogenous DNases, …

Morphological and biochemical characterization and analysis of apoptosis

RT Allen, WJ Hunter III, DK Agrawal - Journal of pharmacological and …, 1997 - Elsevier
… discuss the morphology of apoptosis and discriminate it from necrosis, discuss relevant
biochemical events integral to the … and biochemical features in cells undergoing apoptosis using …

Biochemical pathways of caspase activation during apoptosis

I Budihardjo, H Oliver, M Lutter, X Luo… - Annual review of cell …, 1999 - annualreviews.org
the biochemical pathways of caspase activation have beenrecently elucidated. In this review,
we focus on the two most well-studiedpathways of caspase activation: thethe biochemical

Caspases and apoptosis

GS Salvesen - Essays in biochemistry, 2002 - portlandpress.com
The ability of metazoan cells to undergo programmed cell death is vital to both the precise
development and long-term survival of the … in apoptosis, the ordered dismantling of the cell …

Morphological and biochemical aspects of apoptosis, oncosis and necrosis

S Van Cruchten… - Anatomia, histologia …, 2002 - Wiley Online Library
… that is more confusing and more unintelligible than is the area of apoptosis versus necrosis'.
The present paper presents a short overview of the known apoptotic mechanisms and …