The interaction of TIGIT with PVR and PVRL2 inhibits human NK cell cytotoxicity
N Stanietsky, H Simic, J Arapovic… - Proceedings of the …, 2009 - National Acad Sciences
NK cell cytotoxicity is controlled by numerous NK inhibitory and activating receptors. Most of
the inhibitory receptors bind MHC class I proteins and are expressed in a variegated …
the inhibitory receptors bind MHC class I proteins and are expressed in a variegated …
[HTML][HTML] The coding capacity of SARS-CoV-2
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the cause of the ongoing
coronavirus disease 2019 (COVID-19) pandemic 1. To understand the pathogenicity and …
coronavirus disease 2019 (COVID-19) pandemic 1. To understand the pathogenicity and …
[HTML][HTML] SARS-CoV-2 infects the human kidney and drives fibrosis in kidney organoids
Kidney failure is frequently observed during and after COVID-19, but it remains elusive
whether this is a direct effect of the virus. Here, we report that SARS-CoV-2 directly infects …
whether this is a direct effect of the virus. Here, we report that SARS-CoV-2 directly infects …
Lethal influenza infection in the absence of the natural killer cell receptor gene Ncr1
The elimination of viruses and tumors by natural killer cells is mediated by specific natural
killer cell receptors. To study the in vivo function of a principal activating natural killer cell …
killer cell receptors. To study the in vivo function of a principal activating natural killer cell …
[HTML][HTML] Diagnosis of imported monkeypox, Israel, 2018
N Erez, H Achdout, E Milrot, Y Schwartz… - Emerging infectious …, 2019 - ncbi.nlm.nih.gov
We report a case of monkeypox in a man who returned from Nigeria to Israel in 2018. Virus
was detected in pustule swabs by transmission electron microscopy and PCR and confirmed …
was detected in pustule swabs by transmission electron microscopy and PCR and confirmed …
Inhibition of the NKp30 activating receptor by pp65 of human cytomegalovirus
TI Arnon, H Achdout, O Levi, G Markel, N Saleh… - Nature …, 2005 - nature.com
Human cytomegalovirus, a chief pathogen in immunocompromised people, can persist in a
healthy immunocompetent host throughout life without being eliminated by the immune …
healthy immunocompetent host throughout life without being eliminated by the immune …
A single dose of recombinant VSV-∆ G-spike vaccine provides protection against SARS-CoV-2 challenge
Y Yahalom-Ronen, H Tamir, S Melamed, B Politi… - Nature …, 2020 - nature.com
The COVID-19 pandemic caused by SARS-CoV-2 imposes an urgent need for rapid
development of an efficient and cost-effective vaccine, suitable for mass immunization. Here …
development of an efficient and cost-effective vaccine, suitable for mass immunization. Here …
The mechanisms controlling the recognition of tumor-and virus-infected cells by NKp46
TI Arnon, H Achdout, N Lieberman, R Gazit… - Blood, 2004 - ashpublications.org
The destruction of viral-infected and tumor cells is mediated in part via the lysis receptor of
natural killer (NK) cells, NKp46. The nature, however, of its lysis ligands expressed on target …
natural killer (NK) cells, NKp46. The nature, however, of its lysis ligands expressed on target …
The activating receptor NKp46 is essential for the development of type 1 diabetes
C Gur, A Porgador, M Elboim, R Gazit, S Mizrahi… - Nature …, 2010 - nature.com
The mechanism of action of natural killer (NK) cells in type 1 diabetes is still unknown. Here
we show that the activating receptor NKp46 recognizes mouse and human ligands on …
we show that the activating receptor NKp46 recognizes mouse and human ligands on …
A panel of human neutralizing mAbs targeting SARS-CoV-2 spike at multiple epitopes
T Noy-Porat, E Makdasi, R Alcalay, A Mechaly… - Nature …, 2020 - nature.com
The novel highly transmissible human coronavirus SARS-CoV-2 is the causative agent of
the COVID-19 pandemic. Thus far, there is no approved therapeutic drug specifically …
the COVID-19 pandemic. Thus far, there is no approved therapeutic drug specifically …