與「"author:Bouhaddou M"」相符的使用者個人學術檔案
![]() | Mehdi BouhaddouAssistant Professor, UCLA 在 ucla.edu 的電子郵件地址已通過驗證 被引用 8428 次 |
A SARS-CoV-2 protein interaction map reveals targets for drug repurposing
A newly described coronavirus named severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2), which is the causative agent of coronavirus disease 2019 (COVID-19), has …
(SARS-CoV-2), which is the causative agent of coronavirus disease 2019 (COVID-19), has …
[HTML][HTML] The global phosphorylation landscape of SARS-CoV-2 infection
M Bouhaddou, D Memon, B Meyer, KM White… - Cell, 2020 - cell.com
The causative agent of the coronavirus disease 2019 (COVID-19) pandemic, severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2), has infected millions and killed …
respiratory syndrome coronavirus 2 (SARS-CoV-2), has infected millions and killed …
Evolution of enhanced innate immune evasion by SARS-CoV-2
LG Thorne, M Bouhaddou, AK Reuschl… - Nature, 2022 - nature.com
The emergence of SARS-CoV-2 variants of concern suggests viral adaptation to enhance
human-to-human transmission,. Although much effort has focused on the characterization of …
human-to-human transmission,. Although much effort has focused on the characterization of …
Comparative host-coronavirus protein interaction networks reveal pan-viral disease mechanisms
INTRODUCTION The emergence of three lethal coronaviruses in< 20 years and the urgency
of the COVID-19 pandemic have prompted efforts to develop new therapeutic strategies …
of the COVID-19 pandemic have prompted efforts to develop new therapeutic strategies …
Plitidepsin has potent preclinical efficacy against SARS-CoV-2 by targeting the host protein eEF1A
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) viral proteins interact with
the eukaryotic translation machinery, and inhibitors of translation have potent antiviral …
the eukaryotic translation machinery, and inhibitors of translation have potent antiviral …
Genetic screens identify host factors for SARS-CoV-2 and common cold coronaviruses
The Coronaviridae are a family of viruses that cause disease in humans ranging from mild
respiratory infection to potentially lethal acute respiratory distress syndrome. Finding host …
respiratory infection to potentially lethal acute respiratory distress syndrome. Finding host …
Mutations in SARS-CoV-2 variants of concern link to increased spike cleavage and virus transmission
A Escalera, AS Gonzalez-Reiche, S Aslam, I Mena… - Cell host & …, 2022 - cell.com
SARS-CoV-2 lineages have diverged into highly prevalent variants termed" variants of
concern"(VOCs). Here, we characterized emerging SARS-CoV-2 spike polymorphisms in …
concern"(VOCs). Here, we characterized emerging SARS-CoV-2 spike polymorphisms in …
Defining blood-induced microglia functions in neurodegeneration through multiomic profiling
Blood protein extravasation through a disrupted blood–brain barrier and innate immune
activation are hallmarks of neurological diseases and emerging therapeutic targets …
activation are hallmarks of neurological diseases and emerging therapeutic targets …
The landscape of human cancer proteins targeted by SARS-CoV-2
The mapping of SARS-CoV-2 human protein–protein interactions by Gordon and colleagues
revealed druggable targets that are hijacked by the virus. Here, we highlight several …
revealed druggable targets that are hijacked by the virus. Here, we highlight several …
A protein interaction landscape of breast cancer
INTRODUCTION Advances in DNA sequencing technology have enabled the widespread
analysis of breast tumor genomes, creating a catalog of genetic mutations that may initiate or …
analysis of breast tumor genomes, creating a catalog of genetic mutations that may initiate or …