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Lorenzo Calviello

Fondazione Human Technopole
在 fht.org 的電子郵件地址已通過驗證
被引用 7112 次

A SARS-CoV-2 protein interaction map reveals targets for drug repurposing

DE Gordon, GM Jang, M Bouhaddou, J Xu, K Obernier… - Nature, 2020 - nature.com
A newly described coronavirus named severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2), which is the causative agent of coronavirus disease 2019 (COVID-19), has …

Beyond read-counts: Ribo-seq data analysis to understand the functions of the transcriptome

L Calviello, U Ohler - Trends in Genetics, 2017 - cell.com
By mapping the positions of millions of translating ribosomes in the cell, ribosome profiling
(Ribo-seq) has established its role as a powerful tool to study gene expression. Several …

Detecting actively translated open reading frames in ribosome profiling data

L Calviello, N Mukherjee, E Wyler, H Zauber… - Nature …, 2016 - nature.com
RNA-sequencing protocols can quantify gene expression regulation from transcription to
protein synthesis. Ribosome profiling (Ribo-seq) maps the positions of translating ribosomes …

Pressure autoregulation measurement techniques in adult traumatic brain injury, part II: a scoping review of continuous methods

FA Zeiler, J Donnelly, L Calviello… - Journal of …, 2017 - liebertpub.com
A scoping review of the literature was performed systematically on commonly described
continuous autoregulation measurement techniques in adult traumatic brain injury (TBI) to …

[HTML][HTML] The translational landscape of the human heart

S van Heesch, F Witte, V Schneider-Lunitz, JF Schulz… - Cell, 2019 - cell.com
Gene expression in human tissue has primarily been studied on the transcriptional level,
largely neglecting translational regulation. Here, we analyze the translatomes of 80 human …

Standardized annotation of translated open reading frames

JM Mudge, J Ruiz-Orera, JR Prensner, MA Brunet… - Nature …, 2022 - nature.com
To the Editor—Ribosome profiling (Ribo-seq) has extended our understanding of the
translational 'vocabulary'of the human genome, uncovering thousands of open reading …

Integrated proteogenomic deep sequencing and analytics accurately identify non-canonical peptides in tumor immunopeptidomes

C Chong, M Müller, HS Pak, D Harnett, F Huber… - Nature …, 2020 - nature.com
Efforts to precisely identify tumor human leukocyte antigen (HLA) bound peptides capable of
mediating T cell-based tumor rejection still face important challenges. Recent studies …

Super-resolution ribosome profiling reveals unannotated translation events in Arabidopsis

PY Hsu, L Calviello, HYL Wu, FW Li… - Proceedings of the …, 2016 - National Acad Sciences
Deep sequencing of ribosome footprints (ribosome profiling) maps and quantifies mRNA
translation. Because ribosomes decode mRNA every 3 nt, the periodic property of ribosome …

Extensive identification and analysis of conserved small ORFs in animals

SD Mackowiak, H Zauber, C Bielow, D Thiel, K Kutz… - Genome biology, 2015 - Springer
Background There is increasing evidence that transcripts or transcript regions annotated as
non-coding can harbor functional short open reading frames (sORFs). Loss-of-function …

Integrative classification of human coding and noncoding genes through RNA metabolism profiles

N Mukherjee, L Calviello, A Hirsekorn… - Nature structural & …, 2017 - nature.com
Pervasive transcription of the human genome results in a heterogeneous mix of coding
RNAs and long noncoding RNAs (lncRNAs). Only a small fraction of lncRNAs have …