Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the cause of the ongoing
coronavirus disease 2019 (COVID-19) pandemic 1. To understand the pathogenicity and …

Crohn's disease, and ulcerative colitis, the two main types of chronic inflammatory bowel
disease, are multifactorial conditions of unknown aetiology. A susceptibility locus for Crohn's …

The coronavirus SARS-CoV-2 is the cause of the ongoing pandemic of COVID-19.
Coronaviruses have developed a variety of mechanisms to repress host mRNA translation to …

CARD15/NOD2 encodes a protein involved in bacterial recognition by monocytes. Mutations
in CARD15 have recently been found in patients with Crohn disease (CD), a chronic …

Aims: To test the assumption that epithelioid granulomas found in colonoscopic biopsy
specimens in patients with Crohn's colitis are markers of a different clinical behaviour …

Background: An increased incidence of paediatric Crohn's disease was reported recently by
our group. Aims: To assess the incidence and characteristics of inflammatory bowel disease …

Genome-wide association studies (GWAS) have identified dozens of risk loci for many
complex disorders, including Crohn's disease,. However, common disease-associated …

T cell-mediated immunity plays an important role in controlling SARS-CoV-2 infection, but
the repertoire of naturally processed and presented viral epitopes on class I human …

Background Calprotectin is a protein abundant in neutrophils. Fecal calprotectin can be
used as a marker of gastrointestinal inflammation, and an improved assay has recently been …

Objectives: The protein calprotectin is mainly derived from neutrophils. Increased fecal
excretion of calprotectin has been reported in inflammatory bowel disease. The …