The structure, function and evolution of proteins that bind DNA and RNA
WH Hudson, EA Ortlund - Nature reviews Molecular cell biology, 2014 - nature.com
Proteins that bind both DNA and RNA typify the ability of a single gene product to perform
multiple functions. Such DNA-and RNA-binding proteins (DRBPs) have unique functional …
multiple functions. Such DNA-and RNA-binding proteins (DRBPs) have unique functional …
[HTML][HTML] Technology meets TILs: Deciphering T cell function in the-omics era
T cells are at the center of cancer immunology because of their ability to recognize mutations
in tumor cells and directly mediate cancer cell killing. Immunotherapies to rejuvenate …
in tumor cells and directly mediate cancer cell killing. Immunotherapies to rejuvenate …
Proliferating transitory T cells with an effector-like transcriptional signature emerge from PD-1+ stem-like CD8+ T cells during chronic infection
T cell dysfunction is a characteristic feature of chronic viral infection and cancer. Recent
studies in chronic lymphocytic choriomeningitis virus (LCMV) infection have defined a PD-1+ …
studies in chronic lymphocytic choriomeningitis virus (LCMV) infection have defined a PD-1+ …
An intra-tumoral niche maintains and differentiates stem-like CD8 T cells
Tumour-infiltrating lymphocytes are associated with a survival benefit in several tumour
types and with the response to immunotherapy,,,,,,–. However, the reason some tumours …
types and with the response to immunotherapy,,,,,,–. However, the reason some tumours …
Human antibody responses after dengue virus infection are highly cross-reactive to Zika virus
L Priyamvada, KM Quicke… - Proceedings of the …, 2016 - National Acad Sciences
Zika virus (ZIKV) is an emerging mosquito-borne flavivirus of significant public health
concern. ZIKV shares a high degree of sequence and structural homology compared with …
concern. ZIKV shares a high degree of sequence and structural homology compared with …
Rapid generation of neutralizing antibody responses in COVID-19 patients
MS Suthar, MG Zimmerman, RC Kauffman… - Cell Reports …, 2020 - cell.com
Summary SARS-CoV-2, the virus responsible for COVID-19, is causing a devastating
worldwide pandemic, and there is a pressing need to understand the development …
worldwide pandemic, and there is a pressing need to understand the development …
PD-1 combination therapy with IL-2 modifies CD8+ T cell exhaustion program
Combination therapy with PD-1 blockade and IL-2 is highly effective during chronic
lymphocytic choriomeningitis virus infection. Here we examine the underlying basis for this …
lymphocytic choriomeningitis virus infection. Here we examine the underlying basis for this …
[書籍][B] The Naturalist in La Plata
WH Hudson - 1892 - books.google.com
THE plan I have followed in this work has been to sift and arrange the facts I have gathered
concerning the habits of the animals best known to me, preserving those only, which, in my …
concerning the habits of the animals best known to me, preserving those only, which, in my …
The structural basis of direct glucocorticoid-mediated transrepression
WH Hudson, C Youn, EA Ortlund - Nature structural & molecular …, 2013 - nature.com
A newly discovered negative glucocorticoid response element (nGRE) mediates DNA-
dependent transrepression by the glucocorticoid receptor (GR) across the genome and has …
dependent transrepression by the glucocorticoid receptor (GR) across the genome and has …
[HTML][HTML] Infection-and vaccine-induced antibody binding and neutralization of the B. 1.351 SARS-CoV-2 variant
VV Edara, C Norwood, K Floyd, L Lai… - Cell host & …, 2021 - cell.com
The emergence of SARS-CoV-2 variants with mutations in the spike protein is raising
concerns about the efficacy of infection-or vaccine-induced antibodies. We compared …
concerns about the efficacy of infection-or vaccine-induced antibodies. We compared …