The nucleolus is the most prominent structure in a cell nucleus. It is the site of ribosomal
RNA (rRNA) transcription, pre-rRNA processing and ribosome subunit assembly (reviewed …

Normal renal function is important for the excretion and metabolism of many drugs. Renal
diseases which affect glomerular blood flow and filtration, tubular secretion, reabsorption …

Haloperidol has been used extensively for the treatment of psychotic disorders, and it has
been suggested that the monitoring of plasma haloperidol concentration is clinically useful …

The nucleolus is a key organelle that coordinates the synthesis and assembly of ribosomal
subunits and forms in the nucleus around the repeated ribosomal gene clusters. Because …

Background: The nucleolus is a subnuclear organelle containing the ribosomal RNA gene
clusters and ribosome biogenesis factors. Recent studies suggest it may also have roles in …

Background: The cell nucleus contains distinct classes of subnuclear bodies, including
nucleoli, splicing speckles, Cajal bodies, gems, and PML bodies. Many nuclear proteins are …

The identification of interaction partners in protein complexes is a major goal in cell biology.
Here we present a reliable affinity purification strategy to identify specific interactors that …

We present a new class of phosphorescent cyclometalated iridium (III) polypyridine poly
(ethylene glycol)(PEG) complexes [Ir (N^ C) 2 (bpy–CONH–PEG)](PF 6)(bpy–CONH–PEG …

The eukaryotic nucleolus is involved in ribosome biogenesis and a wide range of other RNA
metabolism and cellular functions. An important step in the functional analysis of the …

Objective: The most common ways of assessing adherence to oral an-tipsychotic
medications in research and in clinical practice are self-report and physician report. This …