與「"author:Miorin L"」相符的使用者個人學術檔案

Lisa Miorin

Research Assistant Professor, Icahn School of Medicine at Mount Sinai
在 mssm.edu 的電子郵件地址已通過驗證
被引用 14552 次

A SARS-CoV-2 protein interaction map reveals targets for drug repurposing

DE Gordon, GM Jang, M Bouhaddou, J Xu, K Obernier… - Nature, 2020 - nature.com
A newly described coronavirus named severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2), which is the causative agent of coronavirus disease 2019 (COVID-19), has …

A serological assay to detect SARS-CoV-2 seroconversion in humans

F Amanat, D Stadlbauer, S Strohmeier, THO Nguyen… - Nature medicine, 2020 - nature.com
Here, we describe a serological enzyme-linked immunosorbent assay for the screening and
identification of human SARS-CoV-2 seroconverters. This assay does not require the …

SARS-CoV-2 Orf6 hijacks Nup98 to block STAT nuclear import and antagonize interferon signaling

L Miorin, T Kehrer… - Proceedings of the …, 2020 - National Acad Sciences
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the causative agent of
the ongoing coronavirus disease 2019 (COVID-19) pandemic that is a serious global health …

Antagonism of type I interferon by flaviviruses

L Miorin, AM Maestre, A Fernandez-Sesma… - Biochemical and …, 2017 - Elsevier
The prompt and tightly controlled induction of type I interferon is a central event of the
immune defense against viral infection. Flaviviruses comprise a large family of arthropod …

[HTML][HTML] The global phosphorylation landscape of SARS-CoV-2 infection

M Bouhaddou, D Memon, B Meyer, KM White… - Cell, 2020 - cell.com
The causative agent of the coronavirus disease 2019 (COVID-19) pandemic, severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2), has infected millions and killed …

Discovery of SARS-CoV-2 antiviral drugs through large-scale compound repurposing

L Riva, S Yuan, X Yin, L Martin-Sancho, N Matsunaga… - Nature, 2020 - nature.com
The emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in 2019
has triggered an ongoing global pandemic of the severe pneumonia-like disease …

Comparative host-coronavirus protein interaction networks reveal pan-viral disease mechanisms

DE Gordon, J Hiatt, M Bouhaddou, VV Rezelj, S Ulferts… - Science, 2020 - science.org
INTRODUCTION The emergence of three lethal coronaviruses in< 20 years and the urgency
of the COVID-19 pandemic have prompted efforts to develop new therapeutic strategies …

Identification of a Universal Group B Streptococcus Vaccine by Multiple Genome Screen

D Maione, I Margarit, CD Rinaudo, V Masignani… - Science, 2005 - science.org
Group B Streptococcus (GBS) is a multiserotype bacterial pathogen representing a major
cause of life-threatening infections in newborns. To develop a broadly protective vaccine, we …

[HTML][HTML] MDA5 governs the innate immune response to SARS-CoV-2 in lung epithelial cells

X Yin, L Riva, Y Pu, L Martin-Sancho, J Kanamune… - Cell reports, 2021 - cell.com
Recent studies have profiled the innate immune signatures in patients infected with severe
acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and suggest that cellular …

Zika virus targets human STAT2 to inhibit type I interferon signaling

A Grant, SS Ponia, S Tripathi, V Balasubramaniam… - Cell host & …, 2016 - cell.com
The ongoing epidemic of Zika virus (ZIKV) illustrates the importance of flaviviruses as
emerging human pathogens. All vector-borne flaviviruses studied thus far have to overcome …